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The map label for this gene is mdtA [H]

Identifier: 167623133

GI number: 167623133

Start: 1457255

End: 1458358

Strand: Reverse

Name: mdtA [H]

Synonym: Shal_1199

Alternate gene names: 167623133

Gene position: 1458358-1457255 (Counterclockwise)

Preceding gene: 167623134

Following gene: 167623132

Centisome position: 27.9

GC content: 48.19

Gene sequence:

>1104_bases
ATGAAACCTTTTTATTACCTTGTTCCCATTATGCTCGTTGTGGCTGGTGCAATCTCCTACAGTAGTTTCTCTGAAGCGAA
ACGAACTGACAGCAAGGATCGCCCTGTTCGTACGGTTCCAGTAGTAACAGGTATTGTTGAGCAGCATGAGCTTTCACAAT
CTCTTTCTCTAATAGGAAAACTCGATGCCGAGCAATCGGTTTTTATCGCACCGCAAATCGCGGGTAAGATCAAATCGATT
CGAGTCAGTACCGAACAAGAGATAGACCAAGGTCAACTATTAGTGCAGCTTGATGATGCCAAAGCACAAGCAGCCCTAGC
TGAGGCAGCGGCTTACTTGGCAGATGAGAAGCGTAAGCTGAAAGAGTTTCTGAAGTTGATCGATCAAAACGCCATCACCA
AAACAGAAATCGATGCGCAAAAAGCCAGCGTCGATATGGCCAATGCTCGCTTAGCCGCCGCGCAAGCCGATCTTGATTAT
CATTATCTCAGCGCGCCCTTTTCTGGCACCACCGGCCTTATCGATTTCAGCCGAGGCAAGATGGTCACTGCCGGCACAGA
GCTATTGACCCTTGACGACCTCTCAAGCATGCGTCTTGATCTGCAGGTGCCTGAACATTACCTATCACAGCTCAGTGTGG
GGATGAAGGTCAGCGCCAAGAGCCGCGCATGGCCAAATCAAGTCTTTATTGGCAAAGTGCTCGCCATTGACTCGCGAGTA
AATCAAGACACCTTAAACCTTAGAGTCAGAGTTCAGTTTGACAATCCTACTCAACAGCTAAAACCTGGCATGATGATGTC
TGCCACCATGCTGTTCCCTAGCGTGTCTGAACCGGTGATCCCTGTACAAGCGCTTGAATACTCAGGCACTAACCGTTTTG
TGTATGTGGTCGGTGAAGATGGCATTGCCAAACGCACTAAGGTGACACTTGGGGCTCGTATCGAAAATGAGGTATTAATT
ACAGAGGGACTCACCATTGGCGATAAAGTCGTGGTGCAAGGCCTAGTCAATATGCGTGATGGTTTGCGAGTCGATGACTT
AGCCGAGTCAGCTGTGGCACAAAAAGAAGATAAACAGCAAGAAATGGCAAGAGGAAGCATCTAA

Upstream 100 bases:

>100_bases
AATATTAACTTCTACTTTTCTTTACTTTACATTGCTTTACCCTACAAGGCTGAAATTTTATCTAAAATAATTCCAACTTT
GGCTGTGTAAGTAATCACTC

Downstream 100 bases:

>100_bases
ATGTGGTTGTCTGATGTTTCAGTAAAACGTCCTGTCGTCGCTATTGTATTGAGTTTATTACTGTGTGTTTTTGGCGCCGT
GTCATTTAGTAAACTTGCCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKPFYYLVPIMLVVAGAISYSSFSEAKRTDSKDRPVRTVPVVTGIVEQHELSQSLSLIGKLDAEQSVFIAPQIAGKIKSI
RVSTEQEIDQGQLLVQLDDAKAQAALAEAAAYLADEKRKLKEFLKLIDQNAITKTEIDAQKASVDMANARLAAAQADLDY
HYLSAPFSGTTGLIDFSRGKMVTAGTELLTLDDLSSMRLDLQVPEHYLSQLSVGMKVSAKSRAWPNQVFIGKVLAIDSRV
NQDTLNLRVRVQFDNPTQQLKPGMMMSATMLFPSVSEPVIPVQALEYSGTNRFVYVVGEDGIAKRTKVTLGARIENEVLI
TEGLTIGDKVVVQGLVNMRDGLRVDDLAESAVAQKEDKQQEMARGSI

Sequences:

>Translated_367_residues
MKPFYYLVPIMLVVAGAISYSSFSEAKRTDSKDRPVRTVPVVTGIVEQHELSQSLSLIGKLDAEQSVFIAPQIAGKIKSI
RVSTEQEIDQGQLLVQLDDAKAQAALAEAAAYLADEKRKLKEFLKLIDQNAITKTEIDAQKASVDMANARLAAAQADLDY
HYLSAPFSGTTGLIDFSRGKMVTAGTELLTLDDLSSMRLDLQVPEHYLSQLSVGMKVSAKSRAWPNQVFIGKVLAIDSRV
NQDTLNLRVRVQFDNPTQQLKPGMMMSATMLFPSVSEPVIPVQALEYSGTNRFVYVVGEDGIAKRTKVTLGARIENEVLI
TEGLTIGDKVVVQGLVNMRDGLRVDDLAESAVAQKEDKQQEMARGSI
>Mature_367_residues
MKPFYYLVPIMLVVAGAISYSSFSEAKRTDSKDRPVRTVPVVTGIVEQHELSQSLSLIGKLDAEQSVFIAPQIAGKIKSI
RVSTEQEIDQGQLLVQLDDAKAQAALAEAAAYLADEKRKLKEFLKLIDQNAITKTEIDAQKASVDMANARLAAAQADLDY
HYLSAPFSGTTGLIDFSRGKMVTAGTELLTLDDLSSMRLDLQVPEHYLSQLSVGMKVSAKSRAWPNQVFIGKVLAIDSRV
NQDTLNLRVRVQFDNPTQQLKPGMMMSATMLFPSVSEPVIPVQALEYSGTNRFVYVVGEDGIAKRTKVTLGARIENEVLI
TEGLTIGDKVVVQGLVNMRDGLRVDDLAESAVAQKEDKQQEMARGSI

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=342, Percent_Identity=24.8538011695906, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87081796, Length=363, Percent_Identity=27.8236914600551, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789665, Length=379, Percent_Identity=25.3298153034301, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786668, Length=392, Percent_Identity=26.2755102040816, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789929, Length=322, Percent_Identity=22.9813664596273, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40177; Mature: 40177

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFYYLVPIMLVVAGAISYSSFSEAKRTDSKDRPVRTVPVVTGIVEQHELSQSLSLIGK
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
LDAEQSVFIAPQIAGKIKSIRVSTEQEIDQGQLLVQLDDAKAQAALAEAAAYLADEKRKL
CCCCCEEEEEHHHHCCCCEEEECCHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
KEFLKLIDQNAITKTEIDAQKASVDMANARLAAAQADLDYHYLSAPFSGTTGLIDFSRGK
HHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCE
MVTAGTELLTLDDLSSMRLDLQVPEHYLSQLSVGMKVSAKSRAWPNQVFIGKVLAIDSRV
EEECCCEEEEECCCCCCEEEEECHHHHHHHHHCCEEEECCCCCCCCCEEEEEEEEECCCC
NQDTLNLRVRVQFDNPTQQLKPGMMMSATMLFPSVSEPVIPVQALEYSGTNRFVYVVGED
CCCEEEEEEEEEECCCHHHHCCCCEEEHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCC
GIAKRTKVTLGARIENEVLITEGLTIGDKVVVQGLVNMRDGLRVDDLAESAVAQKEDKQQ
CCCCEEEEEECCEECCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EMARGSI
HHHCCCC
>Mature Secondary Structure
MKPFYYLVPIMLVVAGAISYSSFSEAKRTDSKDRPVRTVPVVTGIVEQHELSQSLSLIGK
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHC
LDAEQSVFIAPQIAGKIKSIRVSTEQEIDQGQLLVQLDDAKAQAALAEAAAYLADEKRKL
CCCCCEEEEEHHHHCCCCEEEECCHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
KEFLKLIDQNAITKTEIDAQKASVDMANARLAAAQADLDYHYLSAPFSGTTGLIDFSRGK
HHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEECCCE
MVTAGTELLTLDDLSSMRLDLQVPEHYLSQLSVGMKVSAKSRAWPNQVFIGKVLAIDSRV
EEECCCEEEEECCCCCCEEEEECHHHHHHHHHCCEEEECCCCCCCCCEEEEEEEEECCCC
NQDTLNLRVRVQFDNPTQQLKPGMMMSATMLFPSVSEPVIPVQALEYSGTNRFVYVVGED
CCCEEEEEEEEEECCCHHHHCCCCEEEHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCC
GIAKRTKVTLGARIENEVLITEGLTIGDKVVVQGLVNMRDGLRVDDLAESAVAQKEDKQQ
CCCCEEEEEECCEECCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EMARGSI
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA