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The map label for this gene is yafC [C]

Identifier: 167623093

GI number: 167623093

Start: 1409893

End: 1410834

Strand: Direct

Name: yafC [C]

Synonym: Shal_1159

Alternate gene names: 167623093

Gene position: 1409893-1410834 (Clockwise)

Preceding gene: 167623092

Following gene: 167623094

Centisome position: 26.97

GC content: 43.52

Gene sequence:

>942_bases
ATGTTAGAACTTTTAGAACCAATCGCAATTTTTACCCATGTGGCTCGAGCGGGGAGTTTTAGCTCTGCGGCGAGAAAGTT
AGGCATATCAAAGTCTAAAGTCAGTACCCAAGTGGCGGATCTGGAGCATAAGCTTGGCGTTCAGTTGATACAACGTACCA
CAAGAAGCTTGAGTTTAACTGAGGCGGGTCAGTTACTGTATACGCAAGGTGAAGAGCTATTAAGAGATGCCGAACAAGCT
GTTGCTAGCGTTCATAATCTTAATGATGCTACCAGAGGCGTATTGAAAGTCGGGATCTCTCAGTCGTTCGGTACCATGCA
TATCATTCCAGCTTTGCCAGAGTTTATGGCTAAACATCCAGAACTCGAACTTCAAGTTAGTCTGCTTGACCATAAAGTTG
ATGTTGTCAACGAAGGGTTAGATCTATTGCTGACCATGTCAGAGCAATTACCGTTAGGTATGGTTGCTAGACCACTGATG
AAGTGCCAATTTTTGTTAGCAGCTTCACCATCATATGTTGAGAAACACGGTGAACCTAGCCGTCCTGAGCAGCTAGTTGA
TCATAATTGCTTGGTATATCAAGGTGAATGGCATGAGCACAGTATTTGGCAGTTTAAGCAAGGTGATGATTTCTGTGAAA
TAGGCGTATCAGGTAATTTTAGAGTCGATAATGCCCCTGCGCTTAAATCTGCAGCAGTGAGTGGGCTAGGTGTGGTTTAC
CTTGCCAGTTACCTGCTTGAAGATGAGCTTGAGAAGGGCACTCTAGTCCCAATTATGCAGGACTGGCAATTGACTCATCA
TTTGCCACTACAGGCTGTTTATCCAAGACGTAAACACTTGGCTCCAAAGGTTAGTGCCTTTATCGATTTTATAAAAGATC
ATATCGGTACCCCACCATATTGGGATGCACCTTTAAAAGAATTGTATGCAAAACGTAAGTGA

Upstream 100 bases:

>100_bases
GCGTACATATACTCACTTAAGATATTGGTTTTTATATAAAAACAGCATGTCTTAGCGATGGAAGTACTATTACTGTCGTA
AACACCTTAAGGCGATTTAC

Downstream 100 bases:

>100_bases
AATGGGGAAACATTGTTTTCTATTTTAAACAATGTGAAACTGATCTAATGTGGTGAAGGATTATTTGGTTTTTATTCAAT
CACTTAATCCTTGTTACTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MLELLEPIAIFTHVARAGSFSSAARKLGISKSKVSTQVADLEHKLGVQLIQRTTRSLSLTEAGQLLYTQGEELLRDAEQA
VASVHNLNDATRGVLKVGISQSFGTMHIIPALPEFMAKHPELELQVSLLDHKVDVVNEGLDLLLTMSEQLPLGMVARPLM
KCQFLLAASPSYVEKHGEPSRPEQLVDHNCLVYQGEWHEHSIWQFKQGDDFCEIGVSGNFRVDNAPALKSAAVSGLGVVY
LASYLLEDELEKGTLVPIMQDWQLTHHLPLQAVYPRRKHLAPKVSAFIDFIKDHIGTPPYWDAPLKELYAKRK

Sequences:

>Translated_313_residues
MLELLEPIAIFTHVARAGSFSSAARKLGISKSKVSTQVADLEHKLGVQLIQRTTRSLSLTEAGQLLYTQGEELLRDAEQA
VASVHNLNDATRGVLKVGISQSFGTMHIIPALPEFMAKHPELELQVSLLDHKVDVVNEGLDLLLTMSEQLPLGMVARPLM
KCQFLLAASPSYVEKHGEPSRPEQLVDHNCLVYQGEWHEHSIWQFKQGDDFCEIGVSGNFRVDNAPALKSAAVSGLGVVY
LASYLLEDELEKGTLVPIMQDWQLTHHLPLQAVYPRRKHLAPKVSAFIDFIKDHIGTPPYWDAPLKELYAKRK
>Mature_313_residues
MLELLEPIAIFTHVARAGSFSSAARKLGISKSKVSTQVADLEHKLGVQLIQRTTRSLSLTEAGQLLYTQGEELLRDAEQA
VASVHNLNDATRGVLKVGISQSFGTMHIIPALPEFMAKHPELELQVSLLDHKVDVVNEGLDLLLTMSEQLPLGMVARPLM
KCQFLLAASPSYVEKHGEPSRPEQLVDHNCLVYQGEWHEHSIWQFKQGDDFCEIGVSGNFRVDNAPALKSAAVSGLGVVY
LASYLLEDELEKGTLVPIMQDWQLTHHLPLQAVYPRRKHLAPKVSAFIDFIKDHIGTPPYWDAPLKELYAKRK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=30.6397306397306, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789440, Length=299, Percent_Identity=27.7591973244147, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=29.4520547945205, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=28.4745762711864, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=27.8350515463918, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=27.719298245614, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789639, Length=300, Percent_Identity=25, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790011, Length=298, Percent_Identity=26.1744966442953, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786448, Length=289, Percent_Identity=25.9515570934256, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788706, Length=306, Percent_Identity=25.4901960784314, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=27.1812080536913, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788297, Length=303, Percent_Identity=25.7425742574257, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789173, Length=260, Percent_Identity=25.7692307692308, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI157672245, Length=119, Percent_Identity=33.6134453781513, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789506, Length=171, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790262, Length=246, Percent_Identity=25.609756097561, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=194, Percent_Identity=24.7422680412371, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=121, Percent_Identity=33.8842975206612, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786508, Length=149, Percent_Identity=27.5167785234899, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790783, Length=294, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367136, Length=167, Percent_Identity=26.3473053892216, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=24.5614035087719, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34841; Mature: 34841

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLEPIAIFTHVARAGSFSSAARKLGISKSKVSTQVADLEHKLGVQLIQRTTRSLSLT
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EAGQLLYTQGEELLRDAEQAVASVHNLNDATRGVLKVGISQSFGTMHIIPALPEFMAKHP
HHCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCC
ELELQVSLLDHKVDVVNEGLDLLLTMSEQLPLGMVARPLMKCQFLLAASPSYVEKHGEPS
CCEEEEHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
RPEQLVDHNCLVYQGEWHEHSIWQFKQGDDFCEIGVSGNFRVDNAPALKSAAVSGLGVVY
CCHHHHCCCEEEEECCCCCCCCEEECCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHH
LASYLLEDELEKGTLVPIMQDWQLTHHLPLQAVYPRRKHLAPKVSAFIDFIKDHIGTPPY
HHHHHHHHHHCCCCCCCCHHCCCHHHCCCCHHCCCHHHHCCHHHHHHHHHHHHHCCCCCC
WDAPLKELYAKRK
CCCHHHHHHHCCC
>Mature Secondary Structure
MLELLEPIAIFTHVARAGSFSSAARKLGISKSKVSTQVADLEHKLGVQLIQRTTRSLSLT
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
EAGQLLYTQGEELLRDAEQAVASVHNLNDATRGVLKVGISQSFGTMHIIPALPEFMAKHP
HHCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHCCC
ELELQVSLLDHKVDVVNEGLDLLLTMSEQLPLGMVARPLMKCQFLLAASPSYVEKHGEPS
CCEEEEHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
RPEQLVDHNCLVYQGEWHEHSIWQFKQGDDFCEIGVSGNFRVDNAPALKSAAVSGLGVVY
CCHHHHCCCEEEEECCCCCCCCEEECCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHH
LASYLLEDELEKGTLVPIMQDWQLTHHLPLQAVYPRRKHLAPKVSAFIDFIKDHIGTPPY
HHHHHHHHHHCCCCCCCCHHCCCHHHCCCCHHCCCHHHHCCHHHHHHHHHHHHHCCCCCC
WDAPLKELYAKRK
CCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]