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The map label for this gene is hcr [H]

Identifier: 167623038

GI number: 167623038

Start: 1343122

End: 1344213

Strand: Direct

Name: hcr [H]

Synonym: Shal_1104

Alternate gene names: 167623038

Gene position: 1343122-1344213 (Clockwise)

Preceding gene: 167623037

Following gene: 167623039

Centisome position: 25.7

GC content: 46.89

Gene sequence:

>1092_bases
ATGGTAATCAATAAGCAAGCTTCTACAGTGGAGTCGTTTTCTGCAGAGCAGTGGCAGTCAGGTGAGCATCAACTCGTTTG
TGTCGAAAAGTGGAACGAGACTCATGATGTTATCAGTTTTCGCTTTCGTGGGACGACCCCAGTTAAGTTTCACTTTAAAC
CTGGGCAGTTTCTAACCCTCTTACTAGAGATCGATGGAGAGAAAATCGCTCGCAGCTACACCATTAGCTCATCGCCATCT
CGTCCATATTCCATCGTGCTGACCATTAAGCGTATAGAAGGTGGCAAGGTATCAAATTACTTGGCCGATAATCTCGCAGT
CGGTCATATGGTACGGGCTCTTGGACCTGAAGGGGTATTTAATCTACTTGATATTCAGGCTGATAAGTACCTATTTTTGA
GTGCGGGTTGCGGCATCACACCGATGTACTCCATGTCTCGTTGGTTAACCGACACCGAAATTGGCGCTGACATTAGTTTT
CTGCACAGTGCAAAATCGAGTGAAGATCTGATTTTTAAAGACTCATTAGCGCAGATGGCACAGCGCAATGCTCAGTTTAA
TCTTAACTATATCTTAGAGCAGCTAACCTGTGAGGCTGACGTCCATATTGATAGCCGAGCAGGGCGGTTAACTGCCGAAA
AACTCGAGCGTTTAGTGCCGGACTTTAGGAGCCGAACTGTATTTGTCTGTGGTCCTGAGCCTTATATGCAAGCGGTAAAA
GCGCTACTTGAGTCGTTAGAGTTCGATATGACGCAGTTCCACCAAGAAAGCTTCGGCTCATTTAAAGGTGATATGGGCGA
GCTTGCTGCGGCGAAAGACGATAGTGCTAAGGCATCTGGTTTTATGCTCAATATCGGAGAACGACGCCGAGCCTTATCTG
CTGAGCAAACGGTATTAGATGGTATCGAAGCGGAAGGATTACCGATTATTGCTGCATGTCGCTCGGGTGTGTGTGGAGCA
TGCAAGTGTAAAGTCATTGAGGGTGATATCGAGTCTACCAGCCAGATGGCACTGACACCCGATGAAGTAGCCCAAGGTTA
TGTGCTCGCTTGCTCAACTAGGTTAAAGTCAGATGTGACTCTAGAGCTGTAG

Upstream 100 bases:

>100_bases
GCATAATTGCAATCAGTTTAGCTGAACAGTAAGTTTAAAATGGCCGCCACTGAGTGGCCATTTTTCTCTTACAAATTGAA
TCATTAGGTGAAGAGTTATC

Downstream 100 bases:

>100_bases
CTATACAAGCTAAGCTATAAGATAAAAATCTGAAATAATTCAGGAATGAAAGTTGCGTAACTCATCATGAGAAAGTAAGG
TTAAAGACAGGCCATGATGG

Product: oxidoreductase FAD-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MVINKQASTVESFSAEQWQSGEHQLVCVEKWNETHDVISFRFRGTTPVKFHFKPGQFLTLLLEIDGEKIARSYTISSSPS
RPYSIVLTIKRIEGGKVSNYLADNLAVGHMVRALGPEGVFNLLDIQADKYLFLSAGCGITPMYSMSRWLTDTEIGADISF
LHSAKSSEDLIFKDSLAQMAQRNAQFNLNYILEQLTCEADVHIDSRAGRLTAEKLERLVPDFRSRTVFVCGPEPYMQAVK
ALLESLEFDMTQFHQESFGSFKGDMGELAAAKDDSAKASGFMLNIGERRRALSAEQTVLDGIEAEGLPIIAACRSGVCGA
CKCKVIEGDIESTSQMALTPDEVAQGYVLACSTRLKSDVTLEL

Sequences:

>Translated_363_residues
MVINKQASTVESFSAEQWQSGEHQLVCVEKWNETHDVISFRFRGTTPVKFHFKPGQFLTLLLEIDGEKIARSYTISSSPS
RPYSIVLTIKRIEGGKVSNYLADNLAVGHMVRALGPEGVFNLLDIQADKYLFLSAGCGITPMYSMSRWLTDTEIGADISF
LHSAKSSEDLIFKDSLAQMAQRNAQFNLNYILEQLTCEADVHIDSRAGRLTAEKLERLVPDFRSRTVFVCGPEPYMQAVK
ALLESLEFDMTQFHQESFGSFKGDMGELAAAKDDSAKASGFMLNIGERRRALSAEQTVLDGIEAEGLPIIAACRSGVCGA
CKCKVIEGDIESTSQMALTPDEVAQGYVLACSTRLKSDVTLEL
>Mature_363_residues
MVINKQASTVESFSAEQWQSGEHQLVCVEKWNETHDVISFRFRGTTPVKFHFKPGQFLTLLLEIDGEKIARSYTISSSPS
RPYSIVLTIKRIEGGKVSNYLADNLAVGHMVRALGPEGVFNLLDIQADKYLFLSAGCGITPMYSMSRWLTDTEIGADISF
LHSAKSSEDLIFKDSLAQMAQRNAQFNLNYILEQLTCEADVHIDSRAGRLTAEKLERLVPDFRSRTVFVCGPEPYMQAVK
ALLESLEFDMTQFHQESFGSFKGDMGELAAAKDDSAKASGFMLNIGERRRALSAEQTVLDGIEAEGLPIIAACRSGVCGA
CKCKVIEGDIESTSQMALTPDEVAQGYVLACSTRLKSDVTLEL

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI47778923, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI84875541, Length=240, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1787098, Length=312, Percent_Identity=34.9358974358974, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1787658, Length=354, Percent_Identity=30.7909604519774, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788104, Length=309, Percent_Identity=25.2427184466019, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788903, Length=217, Percent_Identity=29.9539170506912, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17563928, Length=262, Percent_Identity=27.8625954198473, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323510, Length=200, Percent_Identity=27, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323552, Length=186, Percent_Identity=24.7311827956989, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40039; Mature: 40039

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVINKQASTVESFSAEQWQSGEHQLVCVEKWNETHDVISFRFRGTTPVKFHFKPGQFLTL
CEECCCHHHHHHHCHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCEEEE
LLEIDGEKIARSYTISSSPSRPYSIVLTIKRIEGGKVSNYLADNLAVGHMVRALGPEGVF
EEEECCCHHEEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCH
NLLDIQADKYLFLSAGCGITPMYSMSRWLTDTEIGADISFLHSAKSSEDLIFKDSLAQMA
HHEEECCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEHHHHHHHH
QRNAQFNLNYILEQLTCEADVHIDSRAGRLTAEKLERLVPDFRSRTVFVCGPEPYMQAVK
HCCCCCCHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHH
ALLESLEFDMTQFHQESFGSFKGDMGELAAAKDDSAKASGFMLNIGERRRALSAEQTVLD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHC
GIEAEGLPIIAACRSGVCGACKCKVIEGDIESTSQMALTPDEVAQGYVLACSTRLKSDVT
CCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEEECHHHHHCCEEEEEECCCCCCEE
LEL
EEC
>Mature Secondary Structure
MVINKQASTVESFSAEQWQSGEHQLVCVEKWNETHDVISFRFRGTTPVKFHFKPGQFLTL
CEECCCHHHHHHHCHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEECCCCEEEE
LLEIDGEKIARSYTISSSPSRPYSIVLTIKRIEGGKVSNYLADNLAVGHMVRALGPEGVF
EEEECCCHHEEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCH
NLLDIQADKYLFLSAGCGITPMYSMSRWLTDTEIGADISFLHSAKSSEDLIFKDSLAQMA
HHEEECCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEEHHHHHHHH
QRNAQFNLNYILEQLTCEADVHIDSRAGRLTAEKLERLVPDFRSRTVFVCGPEPYMQAVK
HCCCCCCHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHH
ALLESLEFDMTQFHQESFGSFKGDMGELAAAKDDSAKASGFMLNIGERRRALSAEQTVLD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHC
GIEAEGLPIIAACRSGVCGACKCKVIEGDIESTSQMALTPDEVAQGYVLACSTRLKSDVT
CCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCEEECHHHHHCCEEEEEECCCCCCEE
LEL
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]