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The map label for this gene is nhaR [H]

Identifier: 167623007

GI number: 167623007

Start: 1312740

End: 1313648

Strand: Direct

Name: nhaR [H]

Synonym: Shal_1073

Alternate gene names: 167623007

Gene position: 1312740-1313648 (Clockwise)

Preceding gene: 167623006

Following gene: 167623008

Centisome position: 25.11

GC content: 43.12

Gene sequence:

>909_bases
ATGGCAAATCTAAACTACAATCATCTCTACTATTTTTGGATGATCCAAAAGAAGGGCTCTGTTGCTAAAGCCGCCGAGGC
ATTATGCTTAACTCCGCAAACGGTTACGGGTCAAATTCGGGTATTAGAAACTAGCCTGAAAGGCAGCTTATTTAAGCGGG
TCGGCCGCACATTAGAACCTACTGAGCTCGGTGAATTGGTATTTCGTTACGCCGATAAGATGTTTAGCTTAAGCTATGAA
ATGTTGGATCTGCTGAATTATCAAAAAGATGAGAACATTTTATTTGAGGTAGGCATTGCCGCAGCCTTGTCAAAAGCCTT
AGCCAGTAGAGTTTTACTTTCGGTTGTGCCGAGTGATGGCTCTATGCATTTAGCCTGCTATGAATCGACTCACGAAGACT
TGATGACTAGGTTACGTGAACATAAGCTGGATATGATCCTCTCGGATTGTGCAGGTGAAAGTCTTAAGTATCCTGAGATC
TTATCAAAGCAATTGGGGGAGTCAGGTATAGCGTTTTTCTCTGCAGAAACTTATTCGAAGCCGTTCCCTGAATGTTTAGA
GCAAGGCAAGTTACTAATCCCTGGAAGACGTAGCTCTCTTGGTCAACAGTTAGTGCGTTGGTTCGACGAGAAAGGGTTGA
ATGTGAGTATTCTCGGTGAGTTTGATGATGCCGCGATGATGAAATCTTTTGGTTTTTTCAAGCAGGGGATCTTTGTTGCT
CCTTCGATTTATAAGCAAGATATTTTAGCCCATGGTATGACCTTACTTGGTGAAACATCAGAAATTAAAGAGGTGTATCA
TGTGATGTTTGCCGAGCGGATGATCCAGCACCCGGCAGTTAAGAGCCTGTTAGAAACCGACTTTACCGAGCTATTCGCTG
GTAACGATTTAAAAGTGCAGCAGTTGTAG

Upstream 100 bases:

>100_bases
TGATTTAATGGACTGTCAACGTCTTAAGTAAGCCTAAAAAAGCTAACGAGGTAACTGAATAAGTTGCCTCGTTTTTATTT
ATAACAACGGTGGCCCAACT

Downstream 100 bases:

>100_bases
CATACTCCTGATAAGGCTATCTTAGTCGACTATCTCAGTCTGAGTTGTGATTAGATATTCGTGCGTAGCAATTATCGACA
CTAAGGCGTGGCAACTGGTA

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MANLNYNHLYYFWMIQKKGSVAKAAEALCLTPQTVTGQIRVLETSLKGSLFKRVGRTLEPTELGELVFRYADKMFSLSYE
MLDLLNYQKDENILFEVGIAAALSKALASRVLLSVVPSDGSMHLACYESTHEDLMTRLREHKLDMILSDCAGESLKYPEI
LSKQLGESGIAFFSAETYSKPFPECLEQGKLLIPGRRSSLGQQLVRWFDEKGLNVSILGEFDDAAMMKSFGFFKQGIFVA
PSIYKQDILAHGMTLLGETSEIKEVYHVMFAERMIQHPAVKSLLETDFTELFAGNDLKVQQL

Sequences:

>Translated_302_residues
MANLNYNHLYYFWMIQKKGSVAKAAEALCLTPQTVTGQIRVLETSLKGSLFKRVGRTLEPTELGELVFRYADKMFSLSYE
MLDLLNYQKDENILFEVGIAAALSKALASRVLLSVVPSDGSMHLACYESTHEDLMTRLREHKLDMILSDCAGESLKYPEI
LSKQLGESGIAFFSAETYSKPFPECLEQGKLLIPGRRSSLGQQLVRWFDEKGLNVSILGEFDDAAMMKSFGFFKQGIFVA
PSIYKQDILAHGMTLLGETSEIKEVYHVMFAERMIQHPAVKSLLETDFTELFAGNDLKVQQL
>Mature_301_residues
ANLNYNHLYYFWMIQKKGSVAKAAEALCLTPQTVTGQIRVLETSLKGSLFKRVGRTLEPTELGELVFRYADKMFSLSYEM
LDLLNYQKDENILFEVGIAAALSKALASRVLLSVVPSDGSMHLACYESTHEDLMTRLREHKLDMILSDCAGESLKYPEIL
SKQLGESGIAFFSAETYSKPFPECLEQGKLLIPGRRSSLGQQLVRWFDEKGLNVSILGEFDDAAMMKSFGFFKQGIFVAP
SIYKQDILAHGMTLLGETSEIKEVYHVMFAERMIQHPAVKSLLETDFTELFAGNDLKVQQL

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=56.9491525423729, Blast_Score=354, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34011; Mature: 33880

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLNYNHLYYFWMIQKKGSVAKAAEALCLTPQTVTGQIRVLETSLKGSLFKRVGRTLEP
CCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCH
TELGELVFRYADKMFSLSYEMLDLLNYQKDENILFEVGIAAALSKALASRVLLSVVPSDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHEECCCC
SMHLACYESTHEDLMTRLREHKLDMILSDCAGESLKYPEILSKQLGESGIAFFSAETYSK
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCCCCC
PFPECLEQGKLLIPGRRSSLGQQLVRWFDEKGLNVSILGEFDDAAMMKSFGFFKQGIFVA
CCHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEC
PSIYKQDILAHGMTLLGETSEIKEVYHVMFAERMIQHPAVKSLLETDFTELFAGNDLKVQ
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEE
QL
CC
>Mature Secondary Structure 
ANLNYNHLYYFWMIQKKGSVAKAAEALCLTPQTVTGQIRVLETSLKGSLFKRVGRTLEP
CCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCH
TELGELVFRYADKMFSLSYEMLDLLNYQKDENILFEVGIAAALSKALASRVLLSVVPSDG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHEECCCC
SMHLACYESTHEDLMTRLREHKLDMILSDCAGESLKYPEILSKQLGESGIAFFSAETYSK
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEECCCCCC
PFPECLEQGKLLIPGRRSSLGQQLVRWFDEKGLNVSILGEFDDAAMMKSFGFFKQGIFVA
CCHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEC
PSIYKQDILAHGMTLLGETSEIKEVYHVMFAERMIQHPAVKSLLETDFTELFAGNDLKVQ
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEE
QL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]