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The map label for this gene is rppH

Identifier: 167623001

GI number: 167623001

Start: 1305773

End: 1306294

Strand: Direct

Name: rppH

Synonym: Shal_1067

Alternate gene names: 167623001

Gene position: 1305773-1306294 (Clockwise)

Preceding gene: 167622998

Following gene: 167623002

Centisome position: 24.98

GC content: 44.64

Gene sequence:

>522_bases
GTGATTGATAGTGACGGCTTTCGCGCAAATGTGGGCATCATTATCTGTAATCGCTTTGGGCAGGTTATGTGGGCAAGACG
GTTTGGCCAACATTCCTGGCAATTTCCTCAGGGTGGCGTTGACGATGGAGAGTCAGCAGAAGAAGCCATGTATCGAGAGT
TATACGAAGAAGTAGGATTAAAGCCAGAACATGTGCAAATTCTAACATCGACGCGATCATGGTTACGCTACCGATTACCT
AAGCGGTTAATCAGACAAGATAGTAAACCCGTGTGTATAGGGCAGAAACAGAAGTGGTTTTTGCTGCAATTGAAAAGTGC
CGAAAACGCTATTGATCTCAATGCCAGCGGTCATCCAGAATTTGATGATTGGCGTTGGGTCAGTTATTGGTATCCCGTAA
GACAAGTTGTTTCTTTTAAGAGAGATGTTTACCGAAAAGTGATGAAAGAGTTCGCTGCGACCACTTTGCCTTTGCAGGTT
AAAGAGTCGAATAACAGAAGACGAGGTATGCGCAGAAGCTAA

Upstream 100 bases:

>100_bases
AAAGACATTTTATCCAAAGGTTTGTGGGTAACTGATATTTGCCGCCGGACACGCTTTATGAAACAATCAAAAGATTAATA
GTTAATAGTTCGGAGTCCAT

Downstream 100 bases:

>100_bases
ATAAGGGAGGTTTGCGGTAGTGCTAAAAACACTGAGAGATATTACACAGGCAGTAGCGTCTTCACGCGATCTTCAATACG
CGTTAGAGCTACTTGTTACG

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLKPEHVQILTSTRSWLRYRLP
KRLIRQDSKPVCIGQKQKWFLLQLKSAENAIDLNASGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAATTLPLQV
KESNNRRRGMRRS

Sequences:

>Translated_173_residues
MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLKPEHVQILTSTRSWLRYRLP
KRLIRQDSKPVCIGQKQKWFLLQLKSAENAIDLNASGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAATTLPLQV
KESNNRRRGMRRS
>Mature_173_residues
MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGLKPEHVQILTSTRSWLRYRLP
KRLIRQDSKPVCIGQKQKWFLLQLKSAENAIDLNASGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAATTLPLQV
KESNNRRRGMRRS

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=159, Percent_Identity=75.4716981132076, Blast_Score=261, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_SHEHH (B0TIU1)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001673295.1
- ProteinModelPortal:   B0TIU1
- SMR:   B0TIU1
- GeneID:   5904772
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1067
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- BioCyc:   SHAL458817:SHAL_1067-MONOMER
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 20500; Mature: 20500

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGL
CCCCCCCEECEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
KPEHVQILTSTRSWLRYRLPKRLIRQDSKPVCIGQKQKWFLLQLKSAENAIDLNASGHPE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCEEECCCCCCCC
FDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAATTLPLQVKESNNRRRGMRRS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDDGESAEEAMYRELYEEVGL
CCCCCCCEECEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
KPEHVQILTSTRSWLRYRLPKRLIRQDSKPVCIGQKQKWFLLQLKSAENAIDLNASGHPE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCEEECCCCCCCC
FDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAATTLPLQVKESNNRRRGMRRS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA