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The map label for this gene is ywbI [H]

Identifier: 167622886

GI number: 167622886

Start: 1163647

End: 1164549

Strand: Direct

Name: ywbI [H]

Synonym: Shal_0946

Alternate gene names: 167622886

Gene position: 1163647-1164549 (Clockwise)

Preceding gene: 167622882

Following gene: 167622890

Centisome position: 22.26

GC content: 50.83

Gene sequence:

>903_bases
ATGGATCTTAAAGCGCTGCACTATTTTACCCAGGTCGTTGACGCAGGTGGTTTTGCCAAGGCGAGTCGCAATGTATTTCT
CACTCAACCCGCACTTTCTAAGGCGATTAAAGCCTTAGAGGAGGAGCTAGATATGGTGTTGCTGGAGCGAGGAAAACGCG
GCACCCAGATTAAGCTTACTGCGGCTGGGGAGGTGGTATATCGTCACGCAGAGCTGTTGATGTCACAGCGCCAATCCATG
CTATCTGAGCTGGACGCACTGAAAAACCTGACGGGCGGTACATTGAAGTTAGGCTTGGCGCCCCTTGGCAGCGCCGAGTT
ATTTGCCCCGGTGATTGCCAAGTTTAGGCTGCAATACCCTAAGGTGGATATGCGGTTGTTGGTTCGTGGTGGTATTGAGC
AAACCTTAGCCCTACAGAAAGATGAGATTGAGTTGGCGACCGGGATTATCGAGTTTGATGGTGAATTCGACGGGTTAAGG
ATCCGCAATGATCCTATGGTCGTGGTTGTGCCTAAAACCCATGCCCTAGCTGAATGTAAGGAGCTGCAACTTAAAGACTT
ACAGTCTCTTTCGCAGGTGATGTTTGAGCCTGAATATGCCCTCTATGAGTTGATCTTAAACGCTTGCGATAAAGCCGGTT
TTATTCCCGCGGAAATAACACGAGTCAGTCATGCCGATTTTGGTATCGCACTGGTCGCGGCAGGCACTGGGATTATGGTG
TTACCGCAAATCATTGCCGAGCGTTATCGCGTCGATGCGGTGGTCAATGTGCCGCTTGCGGCACATGATCTCAGGTGGGA
GCTGTCGCTATTTTGGCGCAAGCAGCAGAGCCTCTCTTTTGCGGCAAAGGCGATGATAGAGCTAGTTAAGCTGCAACTAG
AACAGACTGCCGTGCCCGAATAA

Upstream 100 bases:

>100_bases
CCAAGTGAGCAAATAGGATGATTTAGCATGAGTTTACGCTTGCTTAATTAATAAAAAAAATGAATATTAATAATGTAATC
TATAAATTTTGGTTATCTAA

Downstream 100 bases:

>100_bases
TGCAGAGCTCCCCTCGAATTGTGTGGCAAAGGCGATGATAGAGCTAGTTAAGCTGCAACTAGAACAGACTGCCGTACCCG
CATAATGCAGAGCTCCCCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDLKALHYFTQVVDAGGFAKASRNVFLTQPALSKAIKALEEELDMVLLERGKRGTQIKLTAAGEVVYRHAELLMSQRQSM
LSELDALKNLTGGTLKLGLAPLGSAELFAPVIAKFRLQYPKVDMRLLVRGGIEQTLALQKDEIELATGIIEFDGEFDGLR
IRNDPMVVVVPKTHALAECKELQLKDLQSLSQVMFEPEYALYELILNACDKAGFIPAEITRVSHADFGIALVAAGTGIMV
LPQIIAERYRVDAVVNVPLAAHDLRWELSLFWRKQQSLSFAAKAMIELVKLQLEQTAVPE

Sequences:

>Translated_300_residues
MDLKALHYFTQVVDAGGFAKASRNVFLTQPALSKAIKALEEELDMVLLERGKRGTQIKLTAAGEVVYRHAELLMSQRQSM
LSELDALKNLTGGTLKLGLAPLGSAELFAPVIAKFRLQYPKVDMRLLVRGGIEQTLALQKDEIELATGIIEFDGEFDGLR
IRNDPMVVVVPKTHALAECKELQLKDLQSLSQVMFEPEYALYELILNACDKAGFIPAEITRVSHADFGIALVAAGTGIMV
LPQIIAERYRVDAVVNVPLAAHDLRWELSLFWRKQQSLSFAAKAMIELVKLQLEQTAVPE
>Mature_300_residues
MDLKALHYFTQVVDAGGFAKASRNVFLTQPALSKAIKALEEELDMVLLERGKRGTQIKLTAAGEVVYRHAELLMSQRQSM
LSELDALKNLTGGTLKLGLAPLGSAELFAPVIAKFRLQYPKVDMRLLVRGGIEQTLALQKDEIELATGIIEFDGEFDGLR
IRNDPMVVVVPKTHALAECKELQLKDLQSLSQVMFEPEYALYELILNACDKAGFIPAEITRVSHADFGIALVAAGTGIMV
LPQIIAERYRVDAVVNVPLAAHDLRWELSLFWRKQQSLSFAAKAMIELVKLQLEQTAVPE

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=288, Percent_Identity=26.7361111111111, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=27.4914089347079, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367136, Length=261, Percent_Identity=27.2030651340996, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788887, Length=280, Percent_Identity=27.1428571428571, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790399, Length=306, Percent_Identity=26.797385620915, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=23.5294117647059, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787601, Length=238, Percent_Identity=25.2100840336134, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789639, Length=281, Percent_Identity=25.9786476868327, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788297, Length=132, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788748, Length=293, Percent_Identity=25.5972696245734, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789506, Length=285, Percent_Identity=19.6491228070175, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=122, Percent_Identity=31.1475409836066, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33213; Mature: 33213

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKALHYFTQVVDAGGFAKASRNVFLTQPALSKAIKALEEELDMVLLERGKRGTQIKLT
CCCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
AAGEVVYRHAELLMSQRQSMLSELDALKNLTGGTLKLGLAPLGSAELFAPVIAKFRLQYP
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
KVDMRLLVRGGIEQTLALQKDEIELATGIIEFDGEFDGLRIRNDPMVVVVPKTHALAECK
CCCHHHHHHCCHHHHHHHCCCHHHHHHEEEEECCCCCCEEEECCCEEEEECCCHHHHHHH
ELQLKDLQSLSQVMFEPEYALYELILNACDKAGFIPAEITRVSHADFGIALVAAGTGIMV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCHHH
LPQIIAERYRVDAVVNVPLAAHDLRWELSLFWRKQQSLSFAAKAMIELVKLQLEQTAVPE
HHHHHHHHHHHCEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLKALHYFTQVVDAGGFAKASRNVFLTQPALSKAIKALEEELDMVLLERGKRGTQIKLT
CCCHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
AAGEVVYRHAELLMSQRQSMLSELDALKNLTGGTLKLGLAPLGSAELFAPVIAKFRLQYP
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCC
KVDMRLLVRGGIEQTLALQKDEIELATGIIEFDGEFDGLRIRNDPMVVVVPKTHALAECK
CCCHHHHHHCCHHHHHHHCCCHHHHHHEEEEECCCCCCEEEECCCEEEEECCCHHHHHHH
ELQLKDLQSLSQVMFEPEYALYELILNACDKAGFIPAEITRVSHADFGIALVAAGTGIMV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCHHH
LPQIIAERYRVDAVVNVPLAAHDLRWELSLFWRKQQSLSFAAKAMIELVKLQLEQTAVPE
HHHHHHHHHHHCEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]