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The map label for this gene is cidA1 [H]

Identifier: 167622885

GI number: 167622885

Start: 1163053

End: 1163538

Strand: Reverse

Name: cidA1 [H]

Synonym: Shal_0945

Alternate gene names: 167622885

Gene position: 1163538-1163053 (Counterclockwise)

Preceding gene: 167622887

Following gene: 167622884

Centisome position: 22.26

GC content: 45.68

Gene sequence:

>486_bases
ATGGCAAGCCTTGCCAAACGTGCTCAGGTTAACCTTAAACACCAAGCCCTTACTGGCACACAGATAGCCCTTCTTTGTTT
GTTTGCTTGGGGCTGTCAAATCTTGGCGGACCAGGTTAACTCCCCGATCCCCGGTGGTGTTATCGGCCTTGGGATCTTAT
TGTTACTATTGGCCAGTAAGTTACTGCCCGAGACGAGTGTCAATCTAGGTTCAAGCTGGCTAATTGGCGATCTGCTACTG
TTTTTTATTCCTCCCGTGGTTGCTGTGATTAAATACCAAGATCTACTTGAACATTATGGCGTGGTGCTTATTGGCTCTAT
GCTAATTGCGAGCAGTTGCGTGCTGTTAGGCACAGCATTTACCGTAGATAGGCTATTTAAATATGAGCGTAAAAAGCACC
TAAGAAAACACTTAGCGTCTTCAAAAGCTCAAATTATACCGCTACAGCGTGTCGATTTACCGAGTAAAGAGAGGAAAGCA
GCGTGA

Upstream 100 bases:

>100_bases
CCAAAATTTATAGATTACATTATTAATATTCATTTTTTTTATTAATTAAGCAAGCGTAAACTCATGCTAAATCATCCTAT
TTGCTCACTTGGAACTCATC

Downstream 100 bases:

>100_bases
GCCACTCAGCCATAGGTATATTCTGTTTGGTCTTAACATTGGTAGGCTACTACGCCAGCAAGGCCCTCTATCGTCGTCAA
CGCAAAGTGTGGTTTGCCCC

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MASLAKRAQVNLKHQALTGTQIALLCLFAWGCQILADQVNSPIPGGVIGLGILLLLLASKLLPETSVNLGSSWLIGDLLL
FFIPPVVAVIKYQDLLEHYGVVLIGSMLIASSCVLLGTAFTVDRLFKYERKKHLRKHLASSKAQIIPLQRVDLPSKERKA
A

Sequences:

>Translated_161_residues
MASLAKRAQVNLKHQALTGTQIALLCLFAWGCQILADQVNSPIPGGVIGLGILLLLLASKLLPETSVNLGSSWLIGDLLL
FFIPPVVAVIKYQDLLEHYGVVLIGSMLIASSCVLLGTAFTVDRLFKYERKKHLRKHLASSKAQIIPLQRVDLPSKERKA
A
>Mature_160_residues
ASLAKRAQVNLKHQALTGTQIALLCLFAWGCQILADQVNSPIPGGVIGLGILLLLLASKLLPETSVNLGSSWLIGDLLLF
FIPPVVAVIKYQDLLEHYGVVLIGSMLIASSCVLLGTAFTVDRLFKYERKKHLRKHLASSKAQIIPLQRVDLPSKERKAA

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 17522; Mature: 17391

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLAKRAQVNLKHQALTGTQIALLCLFAWGCQILADQVNSPIPGGVIGLGILLLLLASK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLPETSVNLGSSWLIGDLLLFFIPPVVAVIKYQDLLEHYGVVLIGSMLIASSCVLLGTAF
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVDRLFKYERKKHLRKHLASSKAQIIPLQRVDLPSKERKAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHCCCC
>Mature Secondary Structure 
ASLAKRAQVNLKHQALTGTQIALLCLFAWGCQILADQVNSPIPGGVIGLGILLLLLASK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLPETSVNLGSSWLIGDLLLFFIPPVVAVIKYQDLLEHYGVVLIGSMLIASSCVLLGTAF
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVDRLFKYERKKHLRKHLASSKAQIIPLQRVDLPSKERKAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]