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The map label for this gene is kefC [H]

Identifier: 167622609

GI number: 167622609

Start: 825187

End: 826953

Strand: Reverse

Name: kefC [H]

Synonym: Shal_0669

Alternate gene names: 167622609

Gene position: 826953-825187 (Counterclockwise)

Preceding gene: 167622610

Following gene: 167622608

Centisome position: 15.82

GC content: 44.77

Gene sequence:

>1767_bases
ATGGAACCCGCTATACTCATTATCACCTTAGCCTGCGGTATGTTAGTTAGCCGCGTGGGACTGCCCCCCTTAATTGGCTA
TCTTGTTGCGGGATTTGTGCTGTTTTTGTTCGGTATTGAAGAGTCCAGTTTGCCTATGCTGGAGCAACTTGCCAACCTAG
GTGTCACGCTACTGCTCTTTGCCATTGGTCTTAAATTAGATCTGCGCAGCTTATTTAAAGCAGAGGTTTGGGCAGGCTCC
AGCCTTCATTTAATCGGTTCAATGCTCTTTTTTATCCCACTGCTGAAACTGCTGGGTATATTAGGGCTTGAACAGCTCAC
TGGCCTAGAGATAGATCAGCTAGCGCTACTTGCCTTTGCATTGAGTTTTTCCAGTACGATTTTTGCGGTAAAAATACTGG
AAGATAAAGGTGATATGCAGTCACTTTATGGCCGAGTCGCTATTGGTATCTTGATTATGCAAGATATCTTCGCCGTTGCT
TTCTTAACTATCTCTAAGGGCGATATTCCCTCATATTGGGCACTAGGCTTACTGTTACTGCCGCTAGCAAAGCCTCTCAT
ATATAAAGCCTTCGATCGCGTTGGCCACGGTGAACTGCTAGTGCTATTTGGCTTAGTGATGGCACTCGTGATGGGAGCGG
GCCTATTTGAGCTCGTCGGTTTAAAGCCTGATCTTGGTGCGCTAGTCATAGGTATTTTACTGGCGGGGCACCCTAAATCA
TCAGAGCTGGCTAAATCACTGTTTTACTTTAAAGAGCTATTCTTAGTCGCCTTCTTCTTAACCGTTGGCCTCAATGGCTT
ACCCACCTTCTCCGATATCGGCTTAGCTGCGATTTTAGTACTAATAGTACCGATTAAAGTCATTCTATTTATGTACTTGT
TAACTCACTTTAAGCTGCGTTCTCGTACCGCATTAATGAGCTCGTTTAGCTTAGGTAATTACAGCGAATTTGGCTTAATC
GTTGCGGCAGTTGCGACCTCAAAAGGTTGGCTTCCACCACAATGGATGGTTATTCTCGCTGTTGCACTCAGCTTTAGCTT
CCTGTTTGCCGCGCCGCTCAATACCGCATCTAATCGTTTATATCAGAAATTTCAAAGCAGACTCAAGCGACTAGAGAAAC
CCCCTCTGCACCCAGAAGATAGGCCTATACCTGTAGGCAACCCACGCTTTTTAATCTTAGGTATGGGCCGTATTGGTTCT
GGTGCTTATGATGAGCTTAGAGCCCGTTATGATGGTGAGATTTTAGGTATTGAACATAAGCAAGAATTAGTGGATTTCCA
TATAAAGGAAGGCCGAAACGTGGTGCAAGGTGACGCCTCCGATACCGATTTTTGGGAAAAGCTCGATAGAGCCCCTAACC
TCGAATTGGTGTTGCTGACCATGCCTCACCACGTGGGTAATCAATTTGCGGTTGAACAACTTAAGCTACTGGATTACCAA
GGAAAGCTCAGCGCCATCGTTAAATTTAAAGAAGATGCTCAATCACTTAGCGAGTCAGGGGTGCATAGTGTCTATAACCT
CTATGAGGCTGCAGGTGCAGGTTTGGTTGAACATTTAGTCAAAGAGTTGCTAGCCCCAAGTGGTACCGCACCAGATAACC
CCAATGCAATTAACCATCAAAATGAAGCTAAAATTCCTGCAGACACTGATGTTATCAAGCATCAAACTGAAGCTAAAACT
CCTGCAGATACTGATGTGAGCAAGCAGAAAAAACAAGCAGATAACACCGATACTGCAAATGTTACCAAGCATCAAAATGA
AGCTTGA

Upstream 100 bases:

>100_bases
ATTTAATCACAATTTTCAGTTCAACTTCATAAATTTCTTATACAATGGTGCATCACTATACCCTGGAACCTGGGTATCTA
TTTTATTGAAAAGGAGCATC

Downstream 100 bases:

>100_bases
ACGGTTGATATCTCGCAAAAAAGCTGATTGTATACATTATTCGCTTTATAGCGTATGTTATTTGTCATCGAGTATAAGAT
GACCAATAACATCCAATGCC

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLFAIGLKLDLRSLFKAEVWAGS
SLHLIGSMLFFIPLLKLLGILGLEQLTGLEIDQLALLAFALSFSSTIFAVKILEDKGDMQSLYGRVAIGILIMQDIFAVA
FLTISKGDIPSYWALGLLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVILFMYLLTHFKLRSRTALMSSFSLGNYSEFGLI
VAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASNRLYQKFQSRLKRLEKPPLHPEDRPIPVGNPRFLILGMGRIGS
GAYDELRARYDGEILGIEHKQELVDFHIKEGRNVVQGDASDTDFWEKLDRAPNLELVLLTMPHHVGNQFAVEQLKLLDYQ
GKLSAIVKFKEDAQSLSESGVHSVYNLYEAAGAGLVEHLVKELLAPSGTAPDNPNAINHQNEAKIPADTDVIKHQTEAKT
PADTDVSKQKKQADNTDTANVTKHQNEA

Sequences:

>Translated_588_residues
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLFAIGLKLDLRSLFKAEVWAGS
SLHLIGSMLFFIPLLKLLGILGLEQLTGLEIDQLALLAFALSFSSTIFAVKILEDKGDMQSLYGRVAIGILIMQDIFAVA
FLTISKGDIPSYWALGLLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVILFMYLLTHFKLRSRTALMSSFSLGNYSEFGLI
VAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASNRLYQKFQSRLKRLEKPPLHPEDRPIPVGNPRFLILGMGRIGS
GAYDELRARYDGEILGIEHKQELVDFHIKEGRNVVQGDASDTDFWEKLDRAPNLELVLLTMPHHVGNQFAVEQLKLLDYQ
GKLSAIVKFKEDAQSLSESGVHSVYNLYEAAGAGLVEHLVKELLAPSGTAPDNPNAINHQNEAKIPADTDVIKHQTEAKT
PADTDVSKQKKQADNTDTANVTKHQNEA
>Mature_588_residues
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLFAIGLKLDLRSLFKAEVWAGS
SLHLIGSMLFFIPLLKLLGILGLEQLTGLEIDQLALLAFALSFSSTIFAVKILEDKGDMQSLYGRVAIGILIMQDIFAVA
FLTISKGDIPSYWALGLLLLPLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVILFMYLLTHFKLRSRTALMSSFSLGNYSEFGLI
VAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASNRLYQKFQSRLKRLEKPPLHPEDRPIPVGNPRFLILGMGRIGS
GAYDELRARYDGEILGIEHKQELVDFHIKEGRNVVQGDASDTDFWEKLDRAPNLELVLLTMPHHVGNQFAVEQLKLLDYQ
GKLSAIVKFKEDAQSLSESGVHSVYNLYEAAGAGLVEHLVKELLAPSGTAPDNPNAINHQNEAKIPADTDVIKHQTEAKT
PADTDVSKQKKQADNTDTANVTKHQNEA

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=454, Percent_Identity=27.0925110132159, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786685, Length=542, Percent_Identity=26.5682656826568, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1789749, Length=447, Percent_Identity=25.7270693512304, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 64220; Mature: 64220

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHH
AIGLKLDLRSLFKAEVWAGSSLHLIGSMLFFIPLLKLLGILGLEQLTGLEIDQLALLAFA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LSFSSTIFAVKILEDKGDMQSLYGRVAIGILIMQDIFAVAFLTISKGDIPSYWALGLLLL
HHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
PLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCH
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVILFMYLLTHFKLR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTALMSSFSLGNYSEFGLIVAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASNRL
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YQKFQSRLKRLEKPPLHPEDRPIPVGNPRFLILGMGRIGSGAYDELRARYDGEILGIEHK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEECCHHH
QELVDFHIKEGRNVVQGDASDTDFWEKLDRAPNLELVLLTMPHHVGNQFAVEQLKLLDYQ
HHHHHHHHHCCCCEECCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
GKLSAIVKFKEDAQSLSESGVHSVYNLYEAAGAGLVEHLVKELLAPSGTAPDNPNAINHQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
NEAKIPADTDVIKHQTEAKTPADTDVSKQKKQADNTDTANVTKHQNEA
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEPAILIITLACGMLVSRVGLPPLIGYLVAGFVLFLFGIEESSLPMLEQLANLGVTLLLF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHH
AIGLKLDLRSLFKAEVWAGSSLHLIGSMLFFIPLLKLLGILGLEQLTGLEIDQLALLAFA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LSFSSTIFAVKILEDKGDMQSLYGRVAIGILIMQDIFAVAFLTISKGDIPSYWALGLLLL
HHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
PLAKPLIYKAFDRVGHGELLVLFGLVMALVMGAGLFELVGLKPDLGALVIGILLAGHPKS
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCCH
SELAKSLFYFKELFLVAFFLTVGLNGLPTFSDIGLAAILVLIVPIKVILFMYLLTHFKLR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRTALMSSFSLGNYSEFGLIVAAVATSKGWLPPQWMVILAVALSFSFLFAAPLNTASNRL
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YQKFQSRLKRLEKPPLHPEDRPIPVGNPRFLILGMGRIGSGAYDELRARYDGEILGIEHK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEECCHHH
QELVDFHIKEGRNVVQGDASDTDFWEKLDRAPNLELVLLTMPHHVGNQFAVEQLKLLDYQ
HHHHHHHHHCCCCEECCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCC
GKLSAIVKFKEDAQSLSESGVHSVYNLYEAAGAGLVEHLVKELLAPSGTAPDNPNAINHQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
NEAKIPADTDVIKHQTEAKTPADTDVSKQKKQADNTDTANVTKHQNEA
CCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA