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The map label for this gene is pucD [H]

Identifier: 167622591

GI number: 167622591

Start: 796238

End: 798439

Strand: Direct

Name: pucD [H]

Synonym: Shal_0651

Alternate gene names: 167622591

Gene position: 796238-798439 (Clockwise)

Preceding gene: 167622590

Following gene: 167622592

Centisome position: 15.23

GC content: 46.05

Gene sequence:

>2202_bases
ATGGATAGGGTAAATATTCCATTTAAATGGCAAGAGGCGACAGGGCGATCTCAATTTATTAGCGATCGCCATTTCGATAA
TCTATTAGAGGCGAAACTGTTTCGCTCAACATGTGCAAGGGCCAAGATACTTAATATTACACTGCCCAAGCTCCCCTCCG
GGTATTTTGTCTTTGGTGCAAAAGATGTACCCGGGCGAAACGAGTTACCTATAGTGCTATCTGACTGGCCTGTATTTGCC
AGCAGTGAGGTCCGCTACTTAGGCGAAGTTATTCTGTTGCTTGTGGGGCCCGATCTTAAGGAGCTCGACCGTTTAGCAAA
ATTAATCCACGTAGAATATCAACAGTTAACCCCAGCGTTTACGCCCCAAGATTCGAAACAGCTTATTCAGGGCGCCATTC
ATAATCAAGACGCTATTGATGATCTAAAGAATGTGTTCGACAGACACAAGCTTAATAAAGGCGACTTGGCTGCAGGATTC
TCTCAGGCAGAGCATATATTTGAAGAGTCGATAAGCACTGGATATCAAGAACATATGTATCTTGAAACTCAAGGCATGGT
TGGCTATCACAAAGATGGAAAAGTCGTAATCGAAGGCTCGATGCAGTGCCCTTGGTATGTGCATCACTGTATATCAACAG
TACTGGGAAGCGAGGATGTACGCGTTATACAGACTCCTACTGGCGGAGCTTTTGGTGGTAAGGAGGACTATCCCGATGTA
CTGGCTGGTGCACTTTGTGTTGCCGTGCAAAGATTAAAACAGCCTATAAGGTTAGTACTTTCACGCAATGAGGATATCGC
TTTTACAACTAAACGCCATCCGATTAATTTTCACTATCGCACTGGAGTCGATAGCCAGGGCAAAATTGTGGCTATGGACG
TCAAGGTCGATATCAATGCTGGTGCTTACCTGAGTCTGTCTGGAATCGTCTTGCAGCGGGCCATTACTACCTGCACTAAT
GTTTACGATATCCCTAATGCGACAGTCGAGGCAACGGCTTGGGCGACCAATACCGTGCCTAGCGGTGCCTTTAGAGGGTT
TGGTTCACCACAGACCTGCTTTGGTATTGAGACTCATCTTAATCATATTGCCAATAAATTAGGTTTGGATGCAGCTGAGT
TTAAGCGCGCCCATCTGCTCACCACAAAATCTAAAACGCTCACAGGTGCCGATATCTTTGGCGACCTAGTGCTGGAGAAG
ATGTATGCCGAGATTTGTGAGAGCAGTGATTATCACGCTAAAGTGCAAGCCTATCGCCAGCAGGATAGAGGCGCTAACAA
GTTATCAGGCATTGGAATGGCGCTATTTCAGCATGGTTGCGGTTTTGCTGGCGATCTTGAAGACACCTTAGTTAAGGCTG
TTGTGCGCCTAGTAAAAGATGACAATGATGAGATTGAGATCCAAGTGTCTAATACTGATATTGGCCAAGGATTAAGCCTG
ACATTTTGCAAAATAGTGGCAGATACATTGAAGCGGCCTTTGAGCTCGGTAAGACTCGCAGCGGTCGACACTCAGCATGT
ACCTGATTCGGGTCCAACGGTGGCTTCTCGCTCGATTGTGATTGTGGGTTACTTGTTAGAAAAAGCCGCAGAAAAGTTAA
CCGATATTTGGCTGGGTTGTACAGCACAGAGTGTTGAGCAGAGATATAGCAAACCTGATTACCATCAATGGGATCAGCAG
GCATTTAAAGGCAACGCTTATCAGGCAACCAGTTATGGCATCAATGTGGTCGAGCTTGAAGTGGATAGCGCTACAGGTGT
AAGCGAAATAACAGGATTATGGGCTATCTATGATGTGGGTCATGTCATCGATGAGGCAGTATTCAAGGGACAGATAGACG
GTGGCTTTGTACAGGCATTAGGTTATGGCGGTCTTGAGGTAATGACGCTCGATAGTGAGGGGCGATTCCAGCAAACTAAT
ATGGCCGACTACGTTATTCCTACCGCGTTAGATGTTCCAAAAATTCACAGTTCAGTGGTAGATAACCCCTATCAATACGG
TCCTCAAGGTGCTAAAGGTGGCGGCGAGTTAACTCATAATGGTGGCGCTGCAGCATATTGCGCAGCTATTGAGTGTGCCA
TCAATCATCCTATCAATGCTATCCCAGTGACCCCCGAGGTCGTGTGTTCTTTGCTTTATGGCAAGAAAAGTGGTTTAGAG
TCAATGACTCAAGAGGAGCAAGGCCATGAAAATCAGCTTTAA

Upstream 100 bases:

>100_bases
TTAATCCATTTGCGGCATCTAAAATAAGTCACATGTAAATGTGGCCAGAGCTTTTTAACTTTTTAGCTTTTCGTTAAGAA
AAGTGAGAGTGTGAGGTATT

Downstream 100 bases:

>100_bases
ACTTAATAGCGAATTGGTCACCGTCGATGTCGACCCATTACAACCTTTACTGACCACCCTAAGGGATGAGTTACACATGC
AGGCAGCAAAACAGGGCTGC

Product: xanthine dehydrogenase

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MDRVNIPFKWQEATGRSQFISDRHFDNLLEAKLFRSTCARAKILNITLPKLPSGYFVFGAKDVPGRNELPIVLSDWPVFA
SSEVRYLGEVILLLVGPDLKELDRLAKLIHVEYQQLTPAFTPQDSKQLIQGAIHNQDAIDDLKNVFDRHKLNKGDLAAGF
SQAEHIFEESISTGYQEHMYLETQGMVGYHKDGKVVIEGSMQCPWYVHHCISTVLGSEDVRVIQTPTGGAFGGKEDYPDV
LAGALCVAVQRLKQPIRLVLSRNEDIAFTTKRHPINFHYRTGVDSQGKIVAMDVKVDINAGAYLSLSGIVLQRAITTCTN
VYDIPNATVEATAWATNTVPSGAFRGFGSPQTCFGIETHLNHIANKLGLDAAEFKRAHLLTTKSKTLTGADIFGDLVLEK
MYAEICESSDYHAKVQAYRQQDRGANKLSGIGMALFQHGCGFAGDLEDTLVKAVVRLVKDDNDEIEIQVSNTDIGQGLSL
TFCKIVADTLKRPLSSVRLAAVDTQHVPDSGPTVASRSIVIVGYLLEKAAEKLTDIWLGCTAQSVEQRYSKPDYHQWDQQ
AFKGNAYQATSYGINVVELEVDSATGVSEITGLWAIYDVGHVIDEAVFKGQIDGGFVQALGYGGLEVMTLDSEGRFQQTN
MADYVIPTALDVPKIHSSVVDNPYQYGPQGAKGGGELTHNGGAAAYCAAIECAINHPINAIPVTPEVVCSLLYGKKSGLE
SMTQEEQGHENQL

Sequences:

>Translated_733_residues
MDRVNIPFKWQEATGRSQFISDRHFDNLLEAKLFRSTCARAKILNITLPKLPSGYFVFGAKDVPGRNELPIVLSDWPVFA
SSEVRYLGEVILLLVGPDLKELDRLAKLIHVEYQQLTPAFTPQDSKQLIQGAIHNQDAIDDLKNVFDRHKLNKGDLAAGF
SQAEHIFEESISTGYQEHMYLETQGMVGYHKDGKVVIEGSMQCPWYVHHCISTVLGSEDVRVIQTPTGGAFGGKEDYPDV
LAGALCVAVQRLKQPIRLVLSRNEDIAFTTKRHPINFHYRTGVDSQGKIVAMDVKVDINAGAYLSLSGIVLQRAITTCTN
VYDIPNATVEATAWATNTVPSGAFRGFGSPQTCFGIETHLNHIANKLGLDAAEFKRAHLLTTKSKTLTGADIFGDLVLEK
MYAEICESSDYHAKVQAYRQQDRGANKLSGIGMALFQHGCGFAGDLEDTLVKAVVRLVKDDNDEIEIQVSNTDIGQGLSL
TFCKIVADTLKRPLSSVRLAAVDTQHVPDSGPTVASRSIVIVGYLLEKAAEKLTDIWLGCTAQSVEQRYSKPDYHQWDQQ
AFKGNAYQATSYGINVVELEVDSATGVSEITGLWAIYDVGHVIDEAVFKGQIDGGFVQALGYGGLEVMTLDSEGRFQQTN
MADYVIPTALDVPKIHSSVVDNPYQYGPQGAKGGGELTHNGGAAAYCAAIECAINHPINAIPVTPEVVCSLLYGKKSGLE
SMTQEEQGHENQL
>Mature_733_residues
MDRVNIPFKWQEATGRSQFISDRHFDNLLEAKLFRSTCARAKILNITLPKLPSGYFVFGAKDVPGRNELPIVLSDWPVFA
SSEVRYLGEVILLLVGPDLKELDRLAKLIHVEYQQLTPAFTPQDSKQLIQGAIHNQDAIDDLKNVFDRHKLNKGDLAAGF
SQAEHIFEESISTGYQEHMYLETQGMVGYHKDGKVVIEGSMQCPWYVHHCISTVLGSEDVRVIQTPTGGAFGGKEDYPDV
LAGALCVAVQRLKQPIRLVLSRNEDIAFTTKRHPINFHYRTGVDSQGKIVAMDVKVDINAGAYLSLSGIVLQRAITTCTN
VYDIPNATVEATAWATNTVPSGAFRGFGSPQTCFGIETHLNHIANKLGLDAAEFKRAHLLTTKSKTLTGADIFGDLVLEK
MYAEICESSDYHAKVQAYRQQDRGANKLSGIGMALFQHGCGFAGDLEDTLVKAVVRLVKDDNDEIEIQVSNTDIGQGLSL
TFCKIVADTLKRPLSSVRLAAVDTQHVPDSGPTVASRSIVIVGYLLEKAAEKLTDIWLGCTAQSVEQRYSKPDYHQWDQQ
AFKGNAYQATSYGINVVELEVDSATGVSEITGLWAIYDVGHVIDEAVFKGQIDGGFVQALGYGGLEVMTLDSEGRFQQTN
MADYVIPTALDVPKIHSSVVDNPYQYGPQGAKGGGELTHNGGAAAYCAAIECAINHPINAIPVTPEVVCSLLYGKKSGLE
SMTQEEQGHENQL

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=671, Percent_Identity=28.0178837555887, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI71773480, Length=676, Percent_Identity=25, Blast_Score=187, Evalue=3e-47,
Organism=Escherichia coli, GI1789230, Length=759, Percent_Identity=24.5059288537549, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI1789246, Length=778, Percent_Identity=22.4935732647815, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786478, Length=664, Percent_Identity=22.8915662650602, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=681, Percent_Identity=26.431718061674, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17539860, Length=676, Percent_Identity=23.8165680473373, Blast_Score=162, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI32566215, Length=673, Percent_Identity=22.8826151560178, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI17737937, Length=672, Percent_Identity=26.9345238095238, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24647193, Length=637, Percent_Identity=23.3908948194662, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24647199, Length=655, Percent_Identity=23.6641221374046, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24647197, Length=630, Percent_Identity=22.2222222222222, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24647195, Length=630, Percent_Identity=22.2222222222222, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24647201, Length=657, Percent_Identity=22.6788432267884, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 80174; Mature: 80174

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRVNIPFKWQEATGRSQFISDRHFDNLLEAKLFRSTCARAKILNITLPKLPSGYFVFGA
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEC
KDVPGRNELPIVLSDWPVFASSEVRYLGEVILLLVGPDLKELDRLAKLIHVEYQQLTPAF
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
TPQDSKQLIQGAIHNQDAIDDLKNVFDRHKLNKGDLAAGFSQAEHIFEESISTGYQEHMY
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEE
LETQGMVGYHKDGKVVIEGSMQCPWYVHHCISTVLGSEDVRVIQTPTGGAFGGKEDYPDV
EEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHH
LAGALCVAVQRLKQPIRLVLSRNEDIAFTTKRHPINFHYRTGVDSQGKIVAMDVKVDINA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEEEEEECC
GAYLSLSGIVLQRAITTCTNVYDIPNATVEATAWATNTVPSGAFRGFGSPQTCFGIETHL
CCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCCCCEEHHHHHH
NHIANKLGLDAAEFKRAHLLTTKSKTLTGADIFGDLVLEKMYAEICESSDYHAKVQAYRQ
HHHHHHHCCCHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QDRGANKLSGIGMALFQHGCGFAGDLEDTLVKAVVRLVKDDNDEIEIQVSNTDIGQGLSL
HHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
TFCKIVADTLKRPLSSVRLAAVDTQHVPDSGPTVASRSIVIVGYLLEKAAEKLTDIWLGC
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
TAQSVEQRYSKPDYHQWDQQAFKGNAYQATSYGINVVELEVDSATGVSEITGLWAIYDVG
CHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHH
HVIDEAVFKGQIDGGFVQALGYGGLEVMTLDSEGRFQQTNMADYVIPTALDVPKIHSSVV
HHHHHHHHHCCCCCHHHHHCCCCCEEEEEECCCCCEECCCCCCEECCCCCCCHHHHHHHH
DNPYQYGPQGAKGGGELTHNGGAAAYCAAIECAINHPINAIPVTPEVVCSLLYGKKSGLE
CCCHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHH
SMTQEEQGHENQL
HHHHHHCCCCCCC
>Mature Secondary Structure
MDRVNIPFKWQEATGRSQFISDRHFDNLLEAKLFRSTCARAKILNITLPKLPSGYFVFGA
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEC
KDVPGRNELPIVLSDWPVFASSEVRYLGEVILLLVGPDLKELDRLAKLIHVEYQQLTPAF
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
TPQDSKQLIQGAIHNQDAIDDLKNVFDRHKLNKGDLAAGFSQAEHIFEESISTGYQEHMY
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHEEE
LETQGMVGYHKDGKVVIEGSMQCPWYVHHCISTVLGSEDVRVIQTPTGGAFGGKEDYPDV
EEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHH
LAGALCVAVQRLKQPIRLVLSRNEDIAFTTKRHPINFHYRTGVDSQGKIVAMDVKVDINA
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEEEEEECC
GAYLSLSGIVLQRAITTCTNVYDIPNATVEATAWATNTVPSGAFRGFGSPQTCFGIETHL
CCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCCCCEEHHHHHH
NHIANKLGLDAAEFKRAHLLTTKSKTLTGADIFGDLVLEKMYAEICESSDYHAKVQAYRQ
HHHHHHHCCCHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QDRGANKLSGIGMALFQHGCGFAGDLEDTLVKAVVRLVKDDNDEIEIQVSNTDIGQGLSL
HHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
TFCKIVADTLKRPLSSVRLAAVDTQHVPDSGPTVASRSIVIVGYLLEKAAEKLTDIWLGC
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCC
TAQSVEQRYSKPDYHQWDQQAFKGNAYQATSYGINVVELEVDSATGVSEITGLWAIYDVG
CHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHH
HVIDEAVFKGQIDGGFVQALGYGGLEVMTLDSEGRFQQTNMADYVIPTALDVPKIHSSVV
HHHHHHHHHCCCCCHHHHHCCCCCEEEEEECCCCCEECCCCCCEECCCCCCCHHHHHHHH
DNPYQYGPQGAKGGGELTHNGGAAAYCAAIECAINHPINAIPVTPEVVCSLLYGKKSGLE
CCCHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHH
SMTQEEQGHENQL
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]