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The map label for this gene is rbsK [H]

Identifier: 167622522

GI number: 167622522

Start: 698769

End: 699686

Strand: Direct

Name: rbsK [H]

Synonym: Shal_0582

Alternate gene names: 167622522

Gene position: 698769-699686 (Clockwise)

Preceding gene: 167622521

Following gene: 167622523

Centisome position: 13.37

GC content: 48.58

Gene sequence:

>918_bases
ATGTCTCAGTTAATCGTTTTAGGCAGTGTGAATGCCGACCATGTACTGCAAGTTGCCTCTTTCCCGCGTCCGGGAGAAAC
CTTGCATGGTTACAATTACCAAATTATCCCAGGTGGTAAAGGGGCTAATCAGGCCGTTGCTGCTGCGCGCCTAGGTGCTG
ATACTGGCTTTATCGCTTGTGTGGGAGACGATGGTTTTGGTAGAAACATCCGTCATACCTTTGAGCAAGATGGTATGGAG
GTGTCGGCTGTACATATGGTGGAAAATACCCCAACGGGCATTGCGATGATCCAAGTGGCCGATAGTGGTGAAAACAGTAT
CTGTATTGCTGCCGCCGCTAATGATGCATTAACGACAAAGGTTGTTGAGCAGCACGCCTTGAAAATCGAGCAAGCACAGT
ACTTGCTGATGCAGTTAGAAACGCCACTGCCGGGTATTGAGCTTGCCGCTAGCATTGCTAAAGCCCAAGGAACTCAGGTG
ATATTGAATCCAGCGCCTGCACGTAGTCTGCCTGATACTTTACTGGCGATGGTTGATATCATTACTCCTAACGAGACAGA
AGCTGAGCTATTAACTGGAGTCGCGATTACAGACGCCGATAGCGCCGCTCAAGCTGCGAAAGTACTGCACGATAAAGGCA
TCGTTACTGTGATGATCACCTTAGGTTCAAAAGGCGTGTATTTAAGTGAGCAAGGTGAAGGTAAAATTATTGCGGGCTTT
AAAGTACAAGTGACCGATACTACCGCTGCCGGTGATACTTTTAATGGTGCCTTTGTTACGGCACTGCTCGAAGGCCAGAC
AATAGATAAAGCGATTGTGTTTGCCCATGCTGCGGCGGCGATCTCAGTGACCCGTTTTGGCGCACAAACTTCTATTCCAA
CACGGGAAGAAGTTGAGCAGTTCTTAGCTGCGCACTAA

Upstream 100 bases:

>100_bases
GTGTGCTGCGCCTTTTGAACTTGATTCAAGGCGCGTTTTGCTCTGAGCCCAACATCATAATCGGTTGGCAGCGACTCAGA
GAACATCAAGGAATATGTAA

Downstream 100 bases:

>100_bases
AATCGCACTAGATAGCAGTGAATACTGTTATTGAGAGAGTTATTAATACCGCTTTTAACATAGTGATTCAGATAGGAAGT
TAACCCCCATGGCCACCATG

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSQLIVLGSVNADHVLQVASFPRPGETLHGYNYQIIPGGKGANQAVAAARLGADTGFIACVGDDGFGRNIRHTFEQDGME
VSAVHMVENTPTGIAMIQVADSGENSICIAAAANDALTTKVVEQHALKIEQAQYLLMQLETPLPGIELAASIAKAQGTQV
ILNPAPARSLPDTLLAMVDIITPNETEAELLTGVAITDADSAAQAAKVLHDKGIVTVMITLGSKGVYLSEQGEGKIIAGF
KVQVTDTTAAGDTFNGAFVTALLEGQTIDKAIVFAHAAAAISVTRFGAQTSIPTREEVEQFLAAH

Sequences:

>Translated_305_residues
MSQLIVLGSVNADHVLQVASFPRPGETLHGYNYQIIPGGKGANQAVAAARLGADTGFIACVGDDGFGRNIRHTFEQDGME
VSAVHMVENTPTGIAMIQVADSGENSICIAAAANDALTTKVVEQHALKIEQAQYLLMQLETPLPGIELAASIAKAQGTQV
ILNPAPARSLPDTLLAMVDIITPNETEAELLTGVAITDADSAAQAAKVLHDKGIVTVMITLGSKGVYLSEQGEGKIIAGF
KVQVTDTTAAGDTFNGAFVTALLEGQTIDKAIVFAHAAAAISVTRFGAQTSIPTREEVEQFLAAH
>Mature_304_residues
SQLIVLGSVNADHVLQVASFPRPGETLHGYNYQIIPGGKGANQAVAAARLGADTGFIACVGDDGFGRNIRHTFEQDGMEV
SAVHMVENTPTGIAMIQVADSGENSICIAAAANDALTTKVVEQHALKIEQAQYLLMQLETPLPGIELAASIAKAQGTQVI
LNPAPARSLPDTLLAMVDIITPNETEAELLTGVAITDADSAAQAAKVLHDKGIVTVMITLGSKGVYLSEQGEGKIIAGFK
VQVTDTTAAGDTFNGAFVTALLEGQTIDKAIVFAHAAAAISVTRFGAQTSIPTREEVEQFLAAH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=38.047138047138, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=57.5250836120401, Blast_Score=319, Evalue=2e-88,
Organism=Escherichia coli, GI87081971, Length=281, Percent_Identity=29.1814946619217, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788491, Length=295, Percent_Identity=25.4237288135593, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87082343, Length=304, Percent_Identity=28.9473684210526, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788484, Length=293, Percent_Identity=25.938566552901, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=301, Percent_Identity=38.8704318936877, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI25147470, Length=291, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=29.607250755287, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=37.0860927152318, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24583886, Length=308, Percent_Identity=33.1168831168831, Blast_Score=140, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31756; Mature: 31625

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLIVLGSVNADHVLQVASFPRPGETLHGYNYQIIPGGKGANQAVAAARLGADTGFIAC
CCCEEEEECCCHHHEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCEEEE
VGDDGFGRNIRHTFEQDGMEVSAVHMVENTPTGIAMIQVADSGENSICIAAAANDALTTK
ECCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCHHHHH
VVEQHALKIEQAQYLLMQLETPLPGIELAASIAKAQGTQVILNPAPARSLPDTLLAMVDI
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHE
ITPNETEAELLTGVAITDADSAAQAAKVLHDKGIVTVMITLGSKGVYLSEQGEGKIIAGF
ECCCCCHHHHHEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCEEEEEE
KVQVTDTTAAGDTFNGAFVTALLEGQTIDKAIVFAHAAAAISVTRFGAQTSIPTREEVEQ
EEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHEEEEECCCCCCCCCHHHHHH
FLAAH
HHHCC
>Mature Secondary Structure 
SQLIVLGSVNADHVLQVASFPRPGETLHGYNYQIIPGGKGANQAVAAARLGADTGFIAC
CCEEEEECCCHHHEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCEEEE
VGDDGFGRNIRHTFEQDGMEVSAVHMVENTPTGIAMIQVADSGENSICIAAAANDALTTK
ECCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCHHHHH
VVEQHALKIEQAQYLLMQLETPLPGIELAASIAKAQGTQVILNPAPARSLPDTLLAMVDI
HHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHE
ITPNETEAELLTGVAITDADSAAQAAKVLHDKGIVTVMITLGSKGVYLSEQGEGKIIAGF
ECCCCCHHHHHEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCEEEEEE
KVQVTDTTAAGDTFNGAFVTALLEGQTIDKAIVFAHAAAAISVTRFGAQTSIPTREEVEQ
EEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHEEEEECCCCCCCCCHHHHHH
FLAAH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]