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The map label for this gene is ygbD [C]

Identifier: 167040969

GI number: 167040969

Start: 2400625

End: 2401983

Strand: Reverse

Name: ygbD [C]

Synonym: Teth514_2358

Alternate gene names: 167040969

Gene position: 2401983-2400625 (Counterclockwise)

Preceding gene: 167040970

Following gene: 167040968

Centisome position: 97.75

GC content: 42.68

Gene sequence:

>1359_bases
ATGGCAAAACGATATGTAATTGTGGGCGGCGATGCTGCTGGAATGAGTGCTGCCTCACAAATTAGAAGACAAGACCCGGA
AGGGGAAATCATTGTTTTTGAAAAAGAAGGAGTTATTTCCTATGCCCAATGTGGACTTCCTTATTTTGTAGGGGGAGTAG
TAGCTGAGAAAAAGAAGCTTATCGCTCGTACTGCTGAGGATTTTCATTCTCGCTACAATATTGATGTGCGGTTGTATCAT
GAGGTTTTGCAGTTTAAGCCACAAGACAAACAAGTTCGTGTATATCGTAGGCAAGAAAAAGAAGAGATTATAGTTCCCTA
TGATGTTCTCCTTATTGGGACCGGAAGTGCAGCAATTGTTCCACCTTGGGAAGGGCGCGATTTGCCTGGAGTTTTCACAT
TGAAAACTATGGGAGATGCAGAAAAGCTTTTAGCTTGGCTTGAAGAGCATACTCCTACAAAAGCAGTAGTCATTGGTGGA
GGATATATTGGTTTAGAAACAGCTGAAGCATTACATACAAGGGGATTTAAAGTTACAGTTTTGGATTTAGCTCCTCAGCT
TATTCCGACTTTTGATGCTCCTATTGCTGAAATTGTACAGGATACTCTTAAGCGACACGGCGTGGAAGTGTACTTAAATG
AAGAAGTTGTAGGTTTAGAAGGGGATGAAAAGGGAGTACGGGCAGTTGTGACAAAAAATGGTTCTTTCCCAGCCGATTTA
GTCATTATTTCTATAGGAGTTCGCCCAGTTAGTGAGCTTGCCAGAGAAGCTGGTATAGAGTTAGGCCCTCGAAATGCGAT
TCTTGTAAATGAACGCCTACAAACAAATATTCCAGATATTTTTGCCGCAGGGGATTGCGCTACTCATTTTCATCGCATAA
AAAATGCGCCAGATTATGTGCCATTAGGTACTACGGCTAATAAGCAAGGGCGTATTGCCGGTGTGAACATGGCGGGTGGA
TATGCAAGATTTGCAGGCATTGTCGGTACGGCTATTGTAAAAGTTTTTGATCGCACAATAGCTAGAAGTGGTTTAAGTGA
AAAGGAATGCGATGCTTTAGGTGTGCCATATCAGACTGTTTCTATTAAAGCACGACCTATAAGCCATTATTATCCTTGGG
AAGATGAAGTTTTGACTCTTCGCCTTCACTTCCATAGAGATAATCGCAAGCTTTTGGGAGGTCAGATTGCAGGGGGTGGC
GGTGTAGACAAAAGAATTGATGTTCTTGCTACAGCTCTTTTCCACGGTATGACTATTGATGACCTTCAAGCTTTGGACCT
TGCCTATGCACCTCCATATAACTCAGTGTGGGATCCTCTCCAGCAAGCTGCAACAGTAGTACAAAGAGGGAAAGAATGA

Upstream 100 bases:

>100_bases
TTATTGGCGATATAGTTCACAATTTTAAAGAGTTTGAAAAAATATAAGGTATGAGAGTATAATAAAGATGTGGACATAAG
TACATAAAAGGAGGGAAACC

Downstream 100 bases:

>100_bases
TAGCACCAAGGCCTTACAATAAACGGTAAGGCCTTTTTATTATATCATATTATTTTCACTAAAAAAGTGATTAGACGTCT
GACAAATAACAAAAAATTGT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAKRYVIVGGDAAGMSAASQIRRQDPEGEIIVFEKEGVISYAQCGLPYFVGGVVAEKKKLIARTAEDFHSRYNIDVRLYH
EVLQFKPQDKQVRVYRRQEKEEIIVPYDVLLIGTGSAAIVPPWEGRDLPGVFTLKTMGDAEKLLAWLEEHTPTKAVVIGG
GYIGLETAEALHTRGFKVTVLDLAPQLIPTFDAPIAEIVQDTLKRHGVEVYLNEEVVGLEGDEKGVRAVVTKNGSFPADL
VIISIGVRPVSELAREAGIELGPRNAILVNERLQTNIPDIFAAGDCATHFHRIKNAPDYVPLGTTANKQGRIAGVNMAGG
YARFAGIVGTAIVKVFDRTIARSGLSEKECDALGVPYQTVSIKARPISHYYPWEDEVLTLRLHFHRDNRKLLGGQIAGGG
GVDKRIDVLATALFHGMTIDDLQALDLAYAPPYNSVWDPLQQAATVVQRGKE

Sequences:

>Translated_452_residues
MAKRYVIVGGDAAGMSAASQIRRQDPEGEIIVFEKEGVISYAQCGLPYFVGGVVAEKKKLIARTAEDFHSRYNIDVRLYH
EVLQFKPQDKQVRVYRRQEKEEIIVPYDVLLIGTGSAAIVPPWEGRDLPGVFTLKTMGDAEKLLAWLEEHTPTKAVVIGG
GYIGLETAEALHTRGFKVTVLDLAPQLIPTFDAPIAEIVQDTLKRHGVEVYLNEEVVGLEGDEKGVRAVVTKNGSFPADL
VIISIGVRPVSELAREAGIELGPRNAILVNERLQTNIPDIFAAGDCATHFHRIKNAPDYVPLGTTANKQGRIAGVNMAGG
YARFAGIVGTAIVKVFDRTIARSGLSEKECDALGVPYQTVSIKARPISHYYPWEDEVLTLRLHFHRDNRKLLGGQIAGGG
GVDKRIDVLATALFHGMTIDDLQALDLAYAPPYNSVWDPLQQAATVVQRGKE
>Mature_451_residues
AKRYVIVGGDAAGMSAASQIRRQDPEGEIIVFEKEGVISYAQCGLPYFVGGVVAEKKKLIARTAEDFHSRYNIDVRLYHE
VLQFKPQDKQVRVYRRQEKEEIIVPYDVLLIGTGSAAIVPPWEGRDLPGVFTLKTMGDAEKLLAWLEEHTPTKAVVIGGG
YIGLETAEALHTRGFKVTVLDLAPQLIPTFDAPIAEIVQDTLKRHGVEVYLNEEVVGLEGDEKGVRAVVTKNGSFPADLV
IISIGVRPVSELAREAGIELGPRNAILVNERLQTNIPDIFAAGDCATHFHRIKNAPDYVPLGTTANKQGRIAGVNMAGGY
ARFAGIVGTAIVKVFDRTIARSGLSEKECDALGVPYQTVSIKARPISHYYPWEDEVLTLRLHFHRDNRKLLGGQIAGGGG
VDKRIDVLATALFHGMTIDDLQALDLAYAPPYNSVWDPLQQAATVVQRGKE

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=325, Percent_Identity=27.6923076923077, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI65787454, Length=325, Percent_Identity=27.6923076923077, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI226437568, Length=325, Percent_Identity=27.6923076923077, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI91199540, Length=322, Percent_Identity=26.7080745341615, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789065, Length=295, Percent_Identity=28.8135593220339, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789765, Length=377, Percent_Identity=28.3819628647215, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788892, Length=289, Percent_Identity=30.7958477508651, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786307, Length=319, Percent_Identity=26.6457680250784, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082354, Length=276, Percent_Identity=25.7246376811594, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081717, Length=200, Percent_Identity=32.5, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=285, Percent_Identity=28.0701754385965, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32565766, Length=144, Percent_Identity=31.25, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6325166, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281359715, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281359713, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639250, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18543267, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639252, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24639257, Length=331, Percent_Identity=26.5861027190332, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24585130, Length=332, Percent_Identity=23.1927710843373, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 49454; Mature: 49323

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRYVIVGGDAAGMSAASQIRRQDPEGEIIVFEKEGVISYAQCGLPYFVGGVVAEKKKL
CCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEHHHCCCHHHHHHHHHHHHHH
IARTAEDFHSRYNIDVRLYHEVLQFKPQDKQVRVYRRQEKEEIIVPYDVLLIGTGSAAIV
HHHHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEEEEECCCCEEE
PPWEGRDLPGVFTLKTMGDAEKLLAWLEEHTPTKAVVIGGGYIGLETAEALHTRGFKVTV
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCEECCCHHHHHHHCCCEEEE
LDLAPQLIPTFDAPIAEIVQDTLKRHGVEVYLNEEVVGLEGDEKGVRAVVTKNGSFPADL
EECCCHHHCCCCCCHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCEEEEECCCCCCCEE
VIISIGVRPVSELAREAGIELGPRNAILVNERLQTNIPDIFAAGDCATHFHRIKNAPDYV
EEEEECCCCHHHHHHHCCCEECCCCEEEECCHHHCCCCCEEECCHHHHHHHHHCCCCCEE
PLGTTANKQGRIAGVNMAGGYARFAGIVGTAIVKVFDRTIARSGLSEKECDALGVPYQTV
ECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEEEE
SIKARPISHYYPWEDEVLTLRLHFHRDNRKLLGGQIAGGGGVDKRIDVLATALFHGMTID
EEEEEECCCCCCCCCCEEEEEEEEECCCCEEECCEECCCCCCCHHHHHHHHHHHHCCCHH
DLQALDLAYAPPYNSVWDPLQQAATVVQRGKE
HHHHHHEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKRYVIVGGDAAGMSAASQIRRQDPEGEIIVFEKEGVISYAQCGLPYFVGGVVAEKKKL
CCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEHHHCCCHHHHHHHHHHHHHH
IARTAEDFHSRYNIDVRLYHEVLQFKPQDKQVRVYRRQEKEEIIVPYDVLLIGTGSAAIV
HHHHHHHHHHHCCCCCEEEHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEEEEECCCCEEE
PPWEGRDLPGVFTLKTMGDAEKLLAWLEEHTPTKAVVIGGGYIGLETAEALHTRGFKVTV
CCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCEECCCHHHHHHHCCCEEEE
LDLAPQLIPTFDAPIAEIVQDTLKRHGVEVYLNEEVVGLEGDEKGVRAVVTKNGSFPADL
EECCCHHHCCCCCCHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCEEEEECCCCCCCEE
VIISIGVRPVSELAREAGIELGPRNAILVNERLQTNIPDIFAAGDCATHFHRIKNAPDYV
EEEEECCCCHHHHHHHCCCEECCCCEEEECCHHHCCCCCEEECCHHHHHHHHHCCCCCEE
PLGTTANKQGRIAGVNMAGGYARFAGIVGTAIVKVFDRTIARSGLSEKECDALGVPYQTV
ECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCEEEE
SIKARPISHYYPWEDEVLTLRLHFHRDNRKLLGGQIAGGGGVDKRIDVLATALFHGMTID
EEEEEECCCCCCCCCCEEEEEEEEECCCCEEECCEECCCCCCCHHHHHHHHHHHHCCCHH
DLQALDLAYAPPYNSVWDPLQQAATVVQRGKE
HHHHHHEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]