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The map label for this gene is ccpA [H]

Identifier: 167040820

GI number: 167040820

Start: 2198288

End: 2199301

Strand: Reverse

Name: ccpA [H]

Synonym: Teth514_2197

Alternate gene names: 167040820

Gene position: 2199301-2198288 (Counterclockwise)

Preceding gene: 167040821

Following gene: 167040819

Centisome position: 89.5

GC content: 34.22

Gene sequence:

>1014_bases
ATGGCGACAATAGACGATGTAGCAAAATTAGCAGGAGTTTCTATTGCAACTGTTTCGAGAGTTTTTAATAATAGTCCTTT
AGTAAGTGAAAAAGCCAGACAAAAAGTTTTAAAAGCGGCAGAAGAGCTGGGATACAAACCCAGTATGCCAGCCAGAAGCC
TGGCGATGAAGAAGACAAACACTATAGGGCTAATTGTGCCTGATATATCAAACCCTTACTATGCAGAAGTAGTAAGAGGT
ATTGAAGATGTCTGCAATATTTATAAATACAATATTACTTTGTGCAATGCAGACAATAAAAGAGAAAAAGAATTTCAATA
TATAGAAATGCTAAAAAATCGGTGGGTTGATGGAATAATATTTCACTGTGACTATTTTTCTGAAGAGCATTATAAAGTCT
TTAAAAATGACAATATAAAGGTGGTACTTGCAGGAAGAACAACAAAGTTTGATGTGCCTTATGTAGGAATTGACAATTTT
AAAGCGGCTTATGATGCAGTGAATTATTTGATATCATTAGGCCACAAGAGGATTGGAATTATTCATGGTCCTTTAGGCGA
TATGAAGGAAACCATAGATAGTGTGGATAGGTTAAGGGGATATAAGCAAGCTCTTATTGATAATGGCTTGCCAATTTATG
AGGGTTTTATAAAGGAGGCAAACTTTAAATATAAAAGTGCTTATAATGCTGCAAAAGAGATGTTAAAAGAAAAAATAAAG
CCTACTGCTATATTTGCAATAAGCGATATTATGGCAATGGGGGTAATAAATGCAGTGTTTGATAGTGGACTTTCATGTCC
TGAAGATATTTCTGTGATGGGCTTTGATAATATTGACTTGTCAGAAGCAACAAGACCTTCTCTTACGACTGTATCACAGC
CTATGTATGAAATAGGGGCTGTTGCAGCTAGAATGCTTATAAAAATGTTAAATGGGGAAAATATTGATGAGTATCAGACA
ATTTTAGAGCACAAAATTGTGGTAAGAAATTCTTGTATATCTCTAAAAGATTAA

Upstream 100 bases:

>100_bases
TTTGGGGAATATTTTTTATAAAAAACTCTTGCATTTTTGAAAGAATCATAATATAATATAACTGTAAGCGGTTACAGTAA
ATTGAGAAAAGGGTGTCAAA

Downstream 100 bases:

>100_bases
ATTTTGTTTTATTTTTTAAATTGTAAGCGCTTACAGTTTTAAAGCATGAAAAGCGCAGTGAAGATTTTAAGCTTACGAAA
GGAGAATATGGCATGTCTTA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MATIDDVAKLAGVSIATVSRVFNNSPLVSEKARQKVLKAAEELGYKPSMPARSLAMKKTNTIGLIVPDISNPYYAEVVRG
IEDVCNIYKYNITLCNADNKREKEFQYIEMLKNRWVDGIIFHCDYFSEEHYKVFKNDNIKVVLAGRTTKFDVPYVGIDNF
KAAYDAVNYLISLGHKRIGIIHGPLGDMKETIDSVDRLRGYKQALIDNGLPIYEGFIKEANFKYKSAYNAAKEMLKEKIK
PTAIFAISDIMAMGVINAVFDSGLSCPEDISVMGFDNIDLSEATRPSLTTVSQPMYEIGAVAARMLIKMLNGENIDEYQT
ILEHKIVVRNSCISLKD

Sequences:

>Translated_337_residues
MATIDDVAKLAGVSIATVSRVFNNSPLVSEKARQKVLKAAEELGYKPSMPARSLAMKKTNTIGLIVPDISNPYYAEVVRG
IEDVCNIYKYNITLCNADNKREKEFQYIEMLKNRWVDGIIFHCDYFSEEHYKVFKNDNIKVVLAGRTTKFDVPYVGIDNF
KAAYDAVNYLISLGHKRIGIIHGPLGDMKETIDSVDRLRGYKQALIDNGLPIYEGFIKEANFKYKSAYNAAKEMLKEKIK
PTAIFAISDIMAMGVINAVFDSGLSCPEDISVMGFDNIDLSEATRPSLTTVSQPMYEIGAVAARMLIKMLNGENIDEYQT
ILEHKIVVRNSCISLKD
>Mature_336_residues
ATIDDVAKLAGVSIATVSRVFNNSPLVSEKARQKVLKAAEELGYKPSMPARSLAMKKTNTIGLIVPDISNPYYAEVVRGI
EDVCNIYKYNITLCNADNKREKEFQYIEMLKNRWVDGIIFHCDYFSEEHYKVFKNDNIKVVLAGRTTKFDVPYVGIDNFK
AAYDAVNYLISLGHKRIGIIHGPLGDMKETIDSVDRLRGYKQALIDNGLPIYEGFIKEANFKYKSAYNAAKEMLKEKIKP
TAIFAISDIMAMGVINAVFDSGLSCPEDISVMGFDNIDLSEATRPSLTTVSQPMYEIGAVAARMLIKMLNGENIDEYQTI
LEHKIVVRNSCISLKD

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=335, Percent_Identity=35.5223880597015, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=34.7305389221557, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1787948, Length=341, Percent_Identity=35.4838709677419, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1788474, Length=337, Percent_Identity=32.0474777448071, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789202, Length=332, Percent_Identity=32.8313253012048, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=30.7692307692308, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=28.8753799392097, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI48994940, Length=314, Percent_Identity=28.6624203821656, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787906, Length=324, Percent_Identity=28.3950617283951, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=27.7611940298507, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790715, Length=312, Percent_Identity=27.5641025641026, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789456, Length=307, Percent_Identity=31.5960912052117, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786268, Length=297, Percent_Identity=25.5892255892256, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790689, Length=313, Percent_Identity=22.6837060702875, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37772; Mature: 37641

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDDVAKLAGVSIATVSRVFNNSPLVSEKARQKVLKAAEELGYKPSMPARSLAMKKTN
CCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
TIGLIVPDISNPYYAEVVRGIEDVCNIYKYNITLCNADNKREKEFQYIEMLKNRWVDGII
EEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
FHCDYFSEEHYKVFKNDNIKVVLAGRTTKFDVPYVGIDNFKAAYDAVNYLISLGHKRIGI
EEEECCCCCCCEEEECCCEEEEEECCCEEECCCEECCCCHHHHHHHHHHHHHHCCCEEEE
IHGPLGDMKETIDSVDRLRGYKQALIDNGLPIYEGFIKEANFKYKSAYNAAKEMLKEKIK
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
PTAIFAISDIMAMGVINAVFDSGLSCPEDISVMGFDNIDLSEATRPSLTTVSQPMYEIGA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
VAARMLIKMLNGENIDEYQTILEHKIVVRNSCISLKD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATIDDVAKLAGVSIATVSRVFNNSPLVSEKARQKVLKAAEELGYKPSMPARSLAMKKTN
CCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
TIGLIVPDISNPYYAEVVRGIEDVCNIYKYNITLCNADNKREKEFQYIEMLKNRWVDGII
EEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
FHCDYFSEEHYKVFKNDNIKVVLAGRTTKFDVPYVGIDNFKAAYDAVNYLISLGHKRIGI
EEEECCCCCCCEEEECCCEEEEEECCCEEECCCEECCCCHHHHHHHHHHHHHHCCCEEEE
IHGPLGDMKETIDSVDRLRGYKQALIDNGLPIYEGFIKEANFKYKSAYNAAKEMLKEKIK
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
PTAIFAISDIMAMGVINAVFDSGLSCPEDISVMGFDNIDLSEATRPSLTTVSQPMYEIGA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
VAARMLIKMLNGENIDEYQTILEHKIVVRNSCISLKD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]