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The map label for this gene is nuoE [H]

Identifier: 167040765

GI number: 167040765

Start: 2146307

End: 2146789

Strand: Reverse

Name: nuoE [H]

Synonym: Teth514_2142

Alternate gene names: 167040765

Gene position: 2146789-2146307 (Counterclockwise)

Preceding gene: 167040766

Following gene: 167040764

Centisome position: 87.37

GC content: 34.58

Gene sequence:

>483_bases
ATGGAGACCTTATGCCGAAAATTCGGTGAAGAGAAAGTAGAGAGGTTTAAAAAGGCTTTGGAGGAATTAAAAAATATCCC
TGGCTCTTTGATTGCAATTATGAATGAGGCTCAAGAAATTTTTGGATATCTTCCTATTGAAGTTCAACTTTATATTTCAA
AAGAAATGAATGTGCCTTTGACAGAAATATTTGGAATAGCTACTTTTTATTCAAGGTTTACTTTAAAGCCTTCGGGTAAA
TACAAGATCAATTTGTGTATGGGAACAGCTTGTTATGTAAGAGGAGCTGCAATGGTGCTGGAAAAAATAAAAGAGAAATT
GGGAATTCAAGTAGGTGAAACAACTCCAGATGGGAAATTTTCTTTAGAACCTACTAGATGCCTTGGAGCTTGCGGATTGG
CTCCTGTTATGATGATAAATGGTGAAGTTTTTGGAAGATTAACTCCTGATGATGTTGATGAAATATTGAGTAAATTTGAG
TAA

Upstream 100 bases:

>100_bases
AAAATTTAATAAATATATGATATAATATTGACGAACATTGAATACAAAGTTTACTTAGAGCTTGGAACATGAAATTTTTA
ATTCACAAGGAGGGAAATAA

Downstream 100 bases:

>100_bases
GAGTTTGATTGTTATGAAAGAATTAGCTCTTTATATATTAGATTTGTCACAAAATAGCATAAGAGCGGGAGCAAAAAATA
TTTATATTGAAATAAATATA

Product: NADH dehydrogenase (ubiquinone), 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
METLCRKFGEEKVERFKKALEELKNIPGSLIAIMNEAQEIFGYLPIEVQLYISKEMNVPLTEIFGIATFYSRFTLKPSGK
YKINLCMGTACYVRGAAMVLEKIKEKLGIQVGETTPDGKFSLEPTRCLGACGLAPVMMINGEVFGRLTPDDVDEILSKFE

Sequences:

>Translated_160_residues
METLCRKFGEEKVERFKKALEELKNIPGSLIAIMNEAQEIFGYLPIEVQLYISKEMNVPLTEIFGIATFYSRFTLKPSGK
YKINLCMGTACYVRGAAMVLEKIKEKLGIQVGETTPDGKFSLEPTRCLGACGLAPVMMINGEVFGRLTPDDVDEILSKFE
>Mature_160_residues
METLCRKFGEEKVERFKKALEELKNIPGSLIAIMNEAQEIFGYLPIEVQLYISKEMNVPLTEIFGIATFYSRFTLKPSGK
YKINLCMGTACYVRGAAMVLEKIKEKLGIQVGETTPDGKFSLEPTRCLGACGLAPVMMINGEVFGRLTPDDVDEILSKFE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=152, Percent_Identity=37.5, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1788621, Length=147, Percent_Identity=29.9319727891156, Blast_Score=95, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561328, Length=156, Percent_Identity=41.6666666666667, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI18859877, Length=133, Percent_Identity=39.0977443609023, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21355353, Length=133, Percent_Identity=33.0827067669173, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17885; Mature: 17885

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLCRKFGEEKVERFKKALEELKNIPGSLIAIMNEAQEIFGYLPIEVQLYISKEMNVPL
CCHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCH
TEIFGIATFYSRFTLKPSGKYKINLCMGTACYVRGAAMVLEKIKEKLGIQVGETTPDGKF
HHHHHHHHHHHHHEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCE
SLEPTRCLGACGLAPVMMINGEVFGRLTPDDVDEILSKFE
ECCHHHHHHHCCCHHEEEECCCEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
METLCRKFGEEKVERFKKALEELKNIPGSLIAIMNEAQEIFGYLPIEVQLYISKEMNVPL
CCHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCH
TEIFGIATFYSRFTLKPSGKYKINLCMGTACYVRGAAMVLEKIKEKLGIQVGETTPDGKF
HHHHHHHHHHHHHEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCE
SLEPTRCLGACGLAPVMMINGEVFGRLTPDDVDEILSKFE
ECCHHHHHHHCCCHHEEEECCCEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA