Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 167040750

GI number: 167040750

Start: 2132336

End: 2133433

Strand: Reverse

Name: mrdB [H]

Synonym: Teth514_2127

Alternate gene names: 167040750

Gene position: 2133433-2132336 (Counterclockwise)

Preceding gene: 167040751

Following gene: 167040749

Centisome position: 86.82

GC content: 35.88

Gene sequence:

>1098_bases
ATGTTTGATAAAAAACTTTTAAAAAATTTTGACTGGGGATTGTTAATAGTTGTACTTTTAATATGTGTATATAGTGTTAT
TGTTGTGACAAGTGCCTCTCACACACTTCAAACAGGCTCTTACAGAAAAGTTATTATCCAAATTGCGGCAATTTTAGTAG
GGCTTATTTCTATCGCTCTAATATGTCTTTTTGATTATAATACCCTTGCTAAGTTTTCTACTTTTATATATATTCTCAAC
CTTTTTGGTCTTGTGTTGGTTTTAGCCATAGGAAAGGAAAGTAAGGGTGCACAAAGCTGGATAAGTTTAGGGCCTGTGAA
TATTCAACCTTCCGAATTTTCTAAGTTGGCATTAGTGCTAACTTTGGCGAATATGTTTAGTAAGATGGAAGAAATAAAGA
CTTTTAAAGAGCTTTTGTGGCCAATGGCTTATTTAGGGATTACTTTTGTTGCAGTGATGTTGCAGCCGGATTTAGGGACA
GGGCTTGTATTTATCGCAATTTTTTTAGCCATAGTATATATTTCGGGGATAAGGACAAAGGTATTGGCACAGCTTTTTGC
TTTAGGAATTGCCCTGTTGCCTATTGGATACAAACTATTAAAACCTTACCAGAGAAATAGACTTTTATCCTTTTTAAATC
CGGAACTGGACCCGATGGGAACAGGTTACCATGTGATTCAGTCTAAAATTGCTATCGGTTCAGGAATGTTTTGGGGGAAG
GGGCTTTTTGACGGAAGCCAAACTCAGCTCTATTATCTTCCCGAAGCATGGACAGACTTTATTTTTTCTGTTGTAGGGGA
AGAATTAGGGTTTATAGGGGCATCTATACTAATAGTTCTCTATGCTATTATGTTGTATAGAGCTTGGAAGATTGCTTATA
ATGCTAAGGATAAATATGGTATGCTGGTGGCTGTAGGAATTATTGCTATGTTTACATTTCATATCTTTGAAAATATAGGG
ATGACTATTGGGATAATGCCAATCACAGGTATTCCTCTTCCCTTTATGAGCTATGGTGGAAGTGCAATGGTAGCGAATAT
GATGGCAATAGGACTTTTAGAAAATATAAGCATGAGAAGGCAAAAGATAAACTTTTAG

Upstream 100 bases:

>100_bases
AGGTGATAAGATAACTGGCCTTGAGCCAGTTTTTTTGTATAGTGAAAATTTCATTTGTATGGTATAATACAAGTTGAATT
GCTGAAAAGAGGGGATTAAA

Downstream 100 bases:

>100_bases
GGGGAATTTCCATGAATATAGCTTTGATAGCCCATGACCAAAAAAAAGAACTTATGGTGAATTTCGCAATTGCTTACAAG
CATATCTTTGAAAAATGCAA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MFDKKLLKNFDWGLLIVVLLICVYSVIVVTSASHTLQTGSYRKVIIQIAAILVGLISIALICLFDYNTLAKFSTFIYILN
LFGLVLVLAIGKESKGAQSWISLGPVNIQPSEFSKLALVLTLANMFSKMEEIKTFKELLWPMAYLGITFVAVMLQPDLGT
GLVFIAIFLAIVYISGIRTKVLAQLFALGIALLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAIGSGMFWGK
GLFDGSQTQLYYLPEAWTDFIFSVVGEELGFIGASILIVLYAIMLYRAWKIAYNAKDKYGMLVAVGIIAMFTFHIFENIG
MTIGIMPITGIPLPFMSYGGSAMVANMMAIGLLENISMRRQKINF

Sequences:

>Translated_365_residues
MFDKKLLKNFDWGLLIVVLLICVYSVIVVTSASHTLQTGSYRKVIIQIAAILVGLISIALICLFDYNTLAKFSTFIYILN
LFGLVLVLAIGKESKGAQSWISLGPVNIQPSEFSKLALVLTLANMFSKMEEIKTFKELLWPMAYLGITFVAVMLQPDLGT
GLVFIAIFLAIVYISGIRTKVLAQLFALGIALLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAIGSGMFWGK
GLFDGSQTQLYYLPEAWTDFIFSVVGEELGFIGASILIVLYAIMLYRAWKIAYNAKDKYGMLVAVGIIAMFTFHIFENIG
MTIGIMPITGIPLPFMSYGGSAMVANMMAIGLLENISMRRQKINF
>Mature_365_residues
MFDKKLLKNFDWGLLIVVLLICVYSVIVVTSASHTLQTGSYRKVIIQIAAILVGLISIALICLFDYNTLAKFSTFIYILN
LFGLVLVLAIGKESKGAQSWISLGPVNIQPSEFSKLALVLTLANMFSKMEEIKTFKELLWPMAYLGITFVAVMLQPDLGT
GLVFIAIFLAIVYISGIRTKVLAQLFALGIALLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAIGSGMFWGK
GLFDGSQTQLYYLPEAWTDFIFSVVGEELGFIGASILIVLYAIMLYRAWKIAYNAKDKYGMLVAVGIIAMFTFHIFENIG
MTIGIMPITGIPLPFMSYGGSAMVANMMAIGLLENISMRRQKINF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=343, Percent_Identity=38.1924198250729, Blast_Score=204, Evalue=7e-54,
Organism=Escherichia coli, GI1786277, Length=368, Percent_Identity=32.6086956521739, Blast_Score=175, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40490; Mature: 40490

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKKLLKNFDWGLLIVVLLICVYSVIVVTSASHTLQTGSYRKVIIQIAAILVGLISIAL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ICLFDYNTLAKFSTFIYILNLFGLVLVLAIGKESKGAQSWISLGPVNIQPSEFSKLALVL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
TLANMFSKMEEIKTFKELLWPMAYLGITFVAVMLQPDLGTGLVFIAIFLAIVYISGIRTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VLAQLFALGIALLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAIGSGMFWGK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GLFDGSQTQLYYLPEAWTDFIFSVVGEELGFIGASILIVLYAIMLYRAWKIAYNAKDKYG
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MLVAVGIIAMFTFHIFENIGMTIGIMPITGIPLPFMSYGGSAMVANMMAIGLLENISMRR
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
QKINF
HHCCC
>Mature Secondary Structure
MFDKKLLKNFDWGLLIVVLLICVYSVIVVTSASHTLQTGSYRKVIIQIAAILVGLISIAL
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHH
ICLFDYNTLAKFSTFIYILNLFGLVLVLAIGKESKGAQSWISLGPVNIQPSEFSKLALVL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
TLANMFSKMEEIKTFKELLWPMAYLGITFVAVMLQPDLGTGLVFIAIFLAIVYISGIRTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VLAQLFALGIALLPIGYKLLKPYQRNRLLSFLNPELDPMGTGYHVIQSKIAIGSGMFWGK
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCC
GLFDGSQTQLYYLPEAWTDFIFSVVGEELGFIGASILIVLYAIMLYRAWKIAYNAKDKYG
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MLVAVGIIAMFTFHIFENIGMTIGIMPITGIPLPFMSYGGSAMVANMMAIGLLENISMRR
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
QKINF
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]