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The map label for this gene is obgE

Identifier: 167040736

GI number: 167040736

Start: 2121780

End: 2123051

Strand: Reverse

Name: obgE

Synonym: Teth514_2113

Alternate gene names: 167040736

Gene position: 2123051-2121780 (Counterclockwise)

Preceding gene: 167040737

Following gene: 167040735

Centisome position: 86.4

GC content: 35.85

Gene sequence:

>1272_bases
TTGTTTATAGACACAGCAAGGATATACATAAAAGCTGGAGACGGTGGAAATGGAATTATATCTTTTAGAAGGGAAAAATA
CGTTGCTTATGGTGGGCCGGACGGTGGCGACGGAGGAAAAGGTGGAGATGTTATATTTATAGCAGATCCTAATTTGTCTA
CTTTGTTAGATTTTAAATACAGGAAAAAGTACATTGCGCAAAATGGAGAAAATGGTAGAGGTAAAAATCAATATGGCAAA
AACGGAGAAGATTTGTACATAAAAGTTCCTGTAGGAACCTTGATAATTAACGATGAAACAGGAGAAATTATAGCTGACCT
TGTAAAACCTAATCAAAAAGCTATTGTTTTACGGGGAGGTAAGGGAGGAAGAGGAAATGCTAAATTTGCTACTCCTACTT
TGAAGACTCCTCGTTTCGCTGAAAGCGGTGAAAAAGGCAAAGAAATGTGGGTACGGTTAGAGCTAAAACTTCTCGCTGAT
GTAGGATTAATAGGATTTCCTAATGCAGGGAAATCTACTCTTCTAGCCAGTTGCACAAGAGCAAAACCTAAAATTGCCAA
TTATCCTTTTACAACACTGACACCTAATTTGGGAGTTGTAGAACATAAAGGGAAATCCTTTGTAATGGCAGATATTCCAG
GTTTAATTGAAGGGGCCCACAGAGGCGAAGGATTAGGACATGATTTTTTACGGCACATTGAAAGGACAAAAATGTTGATA
CACGTGGTGGATGTTTCCGCCAGTGAGGGGCGAGACCCTATAGAAGATTTTGAGAAGATAAATGAGGAGCTGAAACTTTA
CAGTGAAAGATTACTTACTTTGTCTCAAATTGTTGCAGCAAATAAAATTGATATACAAAGCGGTAAAGAAAATTTTCCTG
CTTTTGAAAAAGAAATCAAAAAAAGAGGTTATGAGGTATATCCTATATCTGCTTTGACAAAAGTGGGAATTGACAAACTT
TTGGACAAGACTATAGAAATTCTTTCTTCTATTCCGGTTGAGGAGATAAAGGAAGTGCCAGAAGTTATTGTTTATACACC
TCCTGAAGAGGAAGAAACTCTCAATATAGAAGTAAAAGATAATACCTATTATCTTAGCGGTACAAAAATTGACAAACTTT
TAAAAAGAGTAAATTTACAAGATGAACATTCTTTAAGGTACTTTGAAATGCTTCTTAGAAAGAGCGGGGTAATAGATGCT
CTTAAGGAAAAGGGATTTAAAAGTGGTGATACAATAAATGTGAGAGATTTTGAATTTGAATACTATGAATAA

Upstream 100 bases:

>100_bases
CTTTAATTCTGAAAATGCACAGGAAATTATAAAGAAGCTATTAAAAGAGTAAAAAAATACGAGAAGTAGTATATACTATA
AAATAAGGCAGGTGATAGAA

Downstream 100 bases:

>100_bases
AAGTGGAATTTGATTCCACTTTTTTATTTACTTTAATGAGGTCTCAGGGTAAGCTTGTGCAATTTACCTTTTTTAATGTA
TAATGTATAATAATAATATA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MFIDTARIYIKAGDGGNGIISFRREKYVAYGGPDGGDGGKGGDVIFIADPNLSTLLDFKYRKKYIAQNGENGRGKNQYGK
NGEDLYIKVPVGTLIINDETGEIIADLVKPNQKAIVLRGGKGGRGNAKFATPTLKTPRFAESGEKGKEMWVRLELKLLAD
VGLIGFPNAGKSTLLASCTRAKPKIANYPFTTLTPNLGVVEHKGKSFVMADIPGLIEGAHRGEGLGHDFLRHIERTKMLI
HVVDVSASEGRDPIEDFEKINEELKLYSERLLTLSQIVAANKIDIQSGKENFPAFEKEIKKRGYEVYPISALTKVGIDKL
LDKTIEILSSIPVEEIKEVPEVIVYTPPEEEETLNIEVKDNTYYLSGTKIDKLLKRVNLQDEHSLRYFEMLLRKSGVIDA
LKEKGFKSGDTINVRDFEFEYYE

Sequences:

>Translated_423_residues
MFIDTARIYIKAGDGGNGIISFRREKYVAYGGPDGGDGGKGGDVIFIADPNLSTLLDFKYRKKYIAQNGENGRGKNQYGK
NGEDLYIKVPVGTLIINDETGEIIADLVKPNQKAIVLRGGKGGRGNAKFATPTLKTPRFAESGEKGKEMWVRLELKLLAD
VGLIGFPNAGKSTLLASCTRAKPKIANYPFTTLTPNLGVVEHKGKSFVMADIPGLIEGAHRGEGLGHDFLRHIERTKMLI
HVVDVSASEGRDPIEDFEKINEELKLYSERLLTLSQIVAANKIDIQSGKENFPAFEKEIKKRGYEVYPISALTKVGIDKL
LDKTIEILSSIPVEEIKEVPEVIVYTPPEEEETLNIEVKDNTYYLSGTKIDKLLKRVNLQDEHSLRYFEMLLRKSGVIDA
LKEKGFKSGDTINVRDFEFEYYE
>Mature_423_residues
MFIDTARIYIKAGDGGNGIISFRREKYVAYGGPDGGDGGKGGDVIFIADPNLSTLLDFKYRKKYIAQNGENGRGKNQYGK
NGEDLYIKVPVGTLIINDETGEIIADLVKPNQKAIVLRGGKGGRGNAKFATPTLKTPRFAESGEKGKEMWVRLELKLLAD
VGLIGFPNAGKSTLLASCTRAKPKIANYPFTTLTPNLGVVEHKGKSFVMADIPGLIEGAHRGEGLGHDFLRHIERTKMLI
HVVDVSASEGRDPIEDFEKINEELKLYSERLLTLSQIVAANKIDIQSGKENFPAFEKEIKKRGYEVYPISALTKVGIDKL
LDKTIEILSSIPVEEIKEVPEVIVYTPPEEEETLNIEVKDNTYYLSGTKIDKLLKRVNLQDEHSLRYFEMLLRKSGVIDA
LKEKGFKSGDTINVRDFEFEYYE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=41.1214953271028, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI111955139, Length=347, Percent_Identity=37.7521613832853, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI111955063, Length=243, Percent_Identity=39.917695473251, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=36.7647058823529, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4557537, Length=91, Percent_Identity=41.7582417582418, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4758796, Length=113, Percent_Identity=37.1681415929204, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=343, Percent_Identity=46.3556851311953, Blast_Score=261, Evalue=6e-71,
Organism=Escherichia coli, GI1787454, Length=130, Percent_Identity=36.9230769230769, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=40.7294832826748, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17552324, Length=325, Percent_Identity=32.6153846153846, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=35.9375, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=91, Percent_Identity=38.4615384615385, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=87, Percent_Identity=40.2298850574713, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=193, Percent_Identity=41.4507772020725, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6321649, Length=143, Percent_Identity=34.965034965035, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321612, Length=91, Percent_Identity=40.6593406593407, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=37.037037037037, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319499, Length=174, Percent_Identity=32.7586206896552, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129375, Length=323, Percent_Identity=41.7956656346749, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24585318, Length=300, Percent_Identity=37, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24640873, Length=148, Percent_Identity=37.1621621621622, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640877, Length=148, Percent_Identity=37.1621621621622, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640875, Length=148, Percent_Identity=37.1621621621622, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356473, Length=88, Percent_Identity=40.9090909090909, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17981711, Length=100, Percent_Identity=36, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_THEP3 (B0KAB8)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665417.1
- ProteinModelPortal:   B0KAB8
- SMR:   B0KAB8
- GeneID:   5874938
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1431
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   TPSE340099:TETH39_1431-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47082; Mature: 47082

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDTARIYIKAGDGGNGIISFRREKYVAYGGPDGGDGGKGGDVIFIADPNLSTLLDFKY
CEEEEEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHH
RKKYIAQNGENGRGKNQYGKNGEDLYIKVPVGTLIINDETGEIIADLVKPNQKAIVLRGG
HHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHHCCCCCEEEEECC
KGGRGNAKFATPTLKTPRFAESGEKGKEMWVRLELKLLADVGLIGFPNAGKSTLLASCTR
CCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEEEEEEHHCCCEEECCCCCCHHHHHHHHC
AKPKIANYPFTTLTPNLGVVEHKGKSFVMADIPGLIEGAHRGEGLGHDFLRHIERTKMLI
CCCCCCCCCCCEECCCCCEEEECCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHEEEE
HVVDVSASEGRDPIEDFEKINEELKLYSERLLTLSQIVAANKIDIQSGKENFPAFEKEIK
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHH
KRGYEVYPISALTKVGIDKLLDKTIEILSSIPVEEIKEVPEVIVYTPPEEEETLNIEVKD
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCCCCEEEEEEEC
NTYYLSGTKIDKLLKRVNLQDEHSLRYFEMLLRKSGVIDALKEKGFKSGDTINVRDFEFE
CEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEEEEEEE
YYE
ECC
>Mature Secondary Structure
MFIDTARIYIKAGDGGNGIISFRREKYVAYGGPDGGDGGKGGDVIFIADPNLSTLLDFKY
CEEEEEEEEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHH
RKKYIAQNGENGRGKNQYGKNGEDLYIKVPVGTLIINDETGEIIADLVKPNQKAIVLRGG
HHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHHCCCCCEEEEECC
KGGRGNAKFATPTLKTPRFAESGEKGKEMWVRLELKLLADVGLIGFPNAGKSTLLASCTR
CCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEEEEEEHHCCCEEECCCCCCHHHHHHHHC
AKPKIANYPFTTLTPNLGVVEHKGKSFVMADIPGLIEGAHRGEGLGHDFLRHIERTKMLI
CCCCCCCCCCCEECCCCCEEEECCCEEEEECCCHHHHCCCCCCCCCHHHHHHHHHHEEEE
HVVDVSASEGRDPIEDFEKINEELKLYSERLLTLSQIVAANKIDIQSGKENFPAFEKEIK
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHH
KRGYEVYPISALTKVGIDKLLDKTIEILSSIPVEEIKEVPEVIVYTPPEEEETLNIEVKD
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCCCCEEEEEEEC
NTYYLSGTKIDKLLKRVNLQDEHSLRYFEMLLRKSGVIDALKEKGFKSGDTINVRDFEFE
CEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEEEEEEE
YYE
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA