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The map label for this gene is parE [H]

Identifier: 167040513

GI number: 167040513

Start: 1896730

End: 1897686

Strand: Reverse

Name: parE [H]

Synonym: Teth514_1882

Alternate gene names: 167040513

Gene position: 1897686-1896730 (Counterclockwise)

Preceding gene: 167040514

Following gene: 167040512

Centisome position: 77.23

GC content: 33.96

Gene sequence:

>957_bases
ATGAGGGGCTTGCATTTTGATAGCAAGTTAGAGCTGCGGACTGATTTGCAAAAGCCTAAGGCCCAAAAAGGCGAATCTTT
GATTAAAGTTGTGTTGGCTTCTATCTGCAATACAGATATTGAGATAATGAAAGGATACAAGAATTTTAAGGGAATATTAG
GCCATGAATTTGTAGGAATAGTAGAGGAATCTGATGACCCTAATTTAATAGGAAAAAGAGTAGTAGGCGATATCAATATA
GCCTGTGGTAAATGTGACCTTTGTAGAATTGGACTTTACCACCATTGCCGTAATAGAAAAGTATTAGGGATAAAGGATAA
GGATGGCGCTTTTGCTGAATATCTTACGCTGCCAAATAAAAACCTTTATATTGTACCAAATGAAATCAAAGATGAAGAAG
CAGTTTTTACGGAACCTATTGCTGCAGCTTTAGAAATTATTGAGATGTATCACGTAAAACCCACTGATAAAGTAATAATA
ATTGGGGATGGTAAATTATCACAGTTTATTACTCAAGTTGTTGCTCTTACTGGGGCTAATTTATATGTGGTAGGGAAGCA
TCAAGAAAAGCTGGATTACCTAAAAAGTAAAGCAAATATTATTTTACTAGATAATTTAGATAGACTAAGTTTAAAAAATA
AATTTGATATTGCTATTGAATGTACAGGAAATGAAGGAGGTTTGCAATTAGCTCAAGAATTAGTAAAACCTACAGGTACT
ATTATATTAAAAAGTACCTACAATTTCCTTGCTACTCTGAGTCCCACTGATTGGGTTGTTAATGAAATAAAAATGGTAGG
TACGCGGTGTGGACCTATGGAAGCAGCCCTGAGACTACTCCAGAGAAAATTGATTTCTACAGATTATTTGATAAGTGGCA
TCTATTCTTTAGAGGAATATCAAGAGGCTTTTTCAAAAAAGAATAAATTAAAAGCAGTTATAGATCTGCGAAAATAA

Upstream 100 bases:

>100_bases
AGGAAGGACTATATTTTATTCTTTAGATTATTTTGATCCAAAAATATTTAAATTTAAAGTTATACGAAGTCGGTAAATTA
AGTTGGAAGAAGGGATAAGA

Downstream 100 bases:

>100_bases
TGAAGAGGACGAGGTGAAAAAATGAAAGAAATTAAATCAATAGAGTTTAAAAACGAAGTTTTGTATTTAATTGACCAAAG
GAAATTACCTAATAGTTATG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: DOIA dehydrogenase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRGLHFDSKLELRTDLQKPKAQKGESLIKVVLASICNTDIEIMKGYKNFKGILGHEFVGIVEESDDPNLIGKRVVGDINI
ACGKCDLCRIGLYHHCRNRKVLGIKDKDGAFAEYLTLPNKNLYIVPNEIKDEEAVFTEPIAAALEIIEMYHVKPTDKVII
IGDGKLSQFITQVVALTGANLYVVGKHQEKLDYLKSKANIILLDNLDRLSLKNKFDIAIECTGNEGGLQLAQELVKPTGT
IILKSTYNFLATLSPTDWVVNEIKMVGTRCGPMEAALRLLQRKLISTDYLISGIYSLEEYQEAFSKKNKLKAVIDLRK

Sequences:

>Translated_318_residues
MRGLHFDSKLELRTDLQKPKAQKGESLIKVVLASICNTDIEIMKGYKNFKGILGHEFVGIVEESDDPNLIGKRVVGDINI
ACGKCDLCRIGLYHHCRNRKVLGIKDKDGAFAEYLTLPNKNLYIVPNEIKDEEAVFTEPIAAALEIIEMYHVKPTDKVII
IGDGKLSQFITQVVALTGANLYVVGKHQEKLDYLKSKANIILLDNLDRLSLKNKFDIAIECTGNEGGLQLAQELVKPTGT
IILKSTYNFLATLSPTDWVVNEIKMVGTRCGPMEAALRLLQRKLISTDYLISGIYSLEEYQEAFSKKNKLKAVIDLRK
>Mature_318_residues
MRGLHFDSKLELRTDLQKPKAQKGESLIKVVLASICNTDIEIMKGYKNFKGILGHEFVGIVEESDDPNLIGKRVVGDINI
ACGKCDLCRIGLYHHCRNRKVLGIKDKDGAFAEYLTLPNKNLYIVPNEIKDEEAVFTEPIAAALEIIEMYHVKPTDKVII
IGDGKLSQFITQVVALTGANLYVVGKHQEKLDYLKSKANIILLDNLDRLSLKNKFDIAIECTGNEGGLQLAQELVKPTGT
IILKSTYNFLATLSPTDWVVNEIKMVGTRCGPMEAALRLLQRKLISTDYLISGIYSLEEYQEAFSKKNKLKAVIDLRK

Specific function: Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo- inosose (amino-DOI) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. DOIA dehydrogenase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787863, Length=308, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790045, Length=322, Percent_Identity=24.8447204968944, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788075, Length=327, Percent_Identity=24.1590214067278, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI226510992, Length=309, Percent_Identity=24.5954692556634, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788407, Length=308, Percent_Identity=25.3246753246753, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788073, Length=339, Percent_Identity=24.4837758112094, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786825, Length=345, Percent_Identity=23.1884057971014, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790718, Length=298, Percent_Identity=22.4832214765101, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=316, Percent_Identity=22.4683544303797, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550770, Length=308, Percent_Identity=24.6753246753247, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45551930, Length=308, Percent_Identity=24.6753246753247, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221457811, Length=308, Percent_Identity=24.6753246753247, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17137530, Length=326, Percent_Identity=22.0858895705521, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 35568; Mature: 35568

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLHFDSKLELRTDLQKPKAQKGESLIKVVLASICNTDIEIMKGYKNFKGILGHEFVGI
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEE
VEESDDPNLIGKRVVGDINIACGKCDLCRIGLYHHCRNRKVLGIKDKDGAFAEYLTLPNK
EECCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHHEEECCCC
NLYIVPNEIKDEEAVFTEPIAAALEIIEMYHVKPTDKVIIIGDGKLSQFITQVVALTGAN
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCC
LYVVGKHQEKLDYLKSKANIILLDNLDRLSLKNKFDIAIECTGNEGGLQLAQELVKPTGT
EEEEECCHHHHHHHHCCCCEEEEECCCHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCE
IILKSTYNFLATLSPTDWVVNEIKMVGTRCGPMEAALRLLQRKLISTDYLISGIYSLEEY
EEEEECCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAFSKKNKLKAVIDLRK
HHHHHHHCCEEEEEEECC
>Mature Secondary Structure
MRGLHFDSKLELRTDLQKPKAQKGESLIKVVLASICNTDIEIMKGYKNFKGILGHEFVGI
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEE
VEESDDPNLIGKRVVGDINIACGKCDLCRIGLYHHCRNRKVLGIKDKDGAFAEYLTLPNK
EECCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHHEEECCCC
NLYIVPNEIKDEEAVFTEPIAAALEIIEMYHVKPTDKVIIIGDGKLSQFITQVVALTGAN
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCC
LYVVGKHQEKLDYLKSKANIILLDNLDRLSLKNKFDIAIECTGNEGGLQLAQELVKPTGT
EEEEECCHHHHHHHHCCCCEEEEECCCHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCCE
IILKSTYNFLATLSPTDWVVNEIKMVGTRCGPMEAALRLLQRKLISTDYLISGIYSLEEY
EEEEECCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAFSKKNKLKAVIDLRK
HHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA