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The map label for this gene is ttcA [H]

Identifier: 167040443

GI number: 167040443

Start: 1821595

End: 1822302

Strand: Reverse

Name: ttcA [H]

Synonym: Teth514_1810

Alternate gene names: 167040443

Gene position: 1822302-1821595 (Counterclockwise)

Preceding gene: 167040446

Following gene: 167040441

Centisome position: 74.16

GC content: 31.36

Gene sequence:

>708_bases
ATGCAAAAAATACTTGGAAGAATAAGAAGAGCAGTTCAAGATTTTAATATGATACAAGAGGGAGATATAATAGCTGTTGG
TGTTTCAGGAGGAAAAGACAGTGTAACCCTTTTGTATGGATTACATCTTCTTAAAAATTTTTATCCGGAGAAATTTGAGG
TAATGGGATTGATGTTGACGTTAGGTTATGATAATTTTGACCCAACGCCTGTAGAAAATTTTTGCCGAGAAAAAGGGATA
CCTTTTTTTATTAAAGAAACCGATATAAAAAAGATAGTATTTGATTACAGAAAAGAAGAAAATCCATGCTCTTTGTGTGC
GAATTTAAGAAGAGGAGCATTAAATAATTTTGCAAAAGAAAAAGGATGCAACAAAGTGGCTTTAGCACATCATTATGATG
ACTTGATAGATACTTTTATCATGAATTTGTTTTACAATGGCAGGCTTCATACCTTTGAGCCGGTTTCTTTTTTAGACAGG
TCAAAAATTACTGTAATAAGACCTATGATATACGTTAAGGAAAAAGACATAAGAAGTGAGGTTAAAAAGAGTAATTTGCC
TGTTGTTAAAAATCCTTGTCCTGTTGAAGGTCACACAAAAAGACATTATATAAGGAATTTGCTAATAGACTTAAAGAAAG
AAATACCTGAAATAGACAAAAGGATTTTTACAGCGATAAAAAAAGACGTTTTTCACTTTGAAGGATAA

Upstream 100 bases:

>100_bases
CTCACAACTTCTAATAATTTCTTTATATCATAATTAGCTAAAATATTCAATTGTATTGACATATTCCTGTGAATAGTATT
AATATTGAAGGGGTGATAAT

Downstream 100 bases:

>100_bases
ATGCAAAGAAGAATAAAAGTTAGCAAAAAAGAGTATAAAGAAAAAAACAAGGACATTTTCTGCTATTTTTCGACTTAATG
GGGTTTTATAGGGATTGAAC

Product: PP-loop domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQKILGRIRRAVQDFNMIQEGDIIAVGVSGGKDSVTLLYGLHLLKNFYPEKFEVMGLMLTLGYDNFDPTPVENFCREKGI
PFFIKETDIKKIVFDYRKEENPCSLCANLRRGALNNFAKEKGCNKVALAHHYDDLIDTFIMNLFYNGRLHTFEPVSFLDR
SKITVIRPMIYVKEKDIRSEVKKSNLPVVKNPCPVEGHTKRHYIRNLLIDLKKEIPEIDKRIFTAIKKDVFHFEG

Sequences:

>Translated_235_residues
MQKILGRIRRAVQDFNMIQEGDIIAVGVSGGKDSVTLLYGLHLLKNFYPEKFEVMGLMLTLGYDNFDPTPVENFCREKGI
PFFIKETDIKKIVFDYRKEENPCSLCANLRRGALNNFAKEKGCNKVALAHHYDDLIDTFIMNLFYNGRLHTFEPVSFLDR
SKITVIRPMIYVKEKDIRSEVKKSNLPVVKNPCPVEGHTKRHYIRNLLIDLKKEIPEIDKRIFTAIKKDVFHFEG
>Mature_235_residues
MQKILGRIRRAVQDFNMIQEGDIIAVGVSGGKDSVTLLYGLHLLKNFYPEKFEVMGLMLTLGYDNFDPTPVENFCREKGI
PFFIKETDIKKIVFDYRKEENPCSLCANLRRGALNNFAKEKGCNKVALAHHYDDLIDTFIMNLFYNGRLHTFEPVSFLDR
SKITVIRPMIYVKEKDIRSEVKKSNLPVVKNPCPVEGHTKRHYIRNLLIDLKKEIPEIDKRIFTAIKKDVFHFEG

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=236, Percent_Identity=35.1694915254237, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193211090, Length=230, Percent_Identity=29.5652173913043, Blast_Score=120, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17540090, Length=220, Percent_Identity=25.9090909090909, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24651972, Length=223, Percent_Identity=25.5605381165919, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 27272; Mature: 27272

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKILGRIRRAVQDFNMIQEGDIIAVGVSGGKDSVTLLYGLHLLKNFYPEKFEVMGLMLT
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHE
LGYDNFDPTPVENFCREKGIPFFIKETDIKKIVFDYRKEENPCSLCANLRRGALNNFAKE
ECCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KGCNKVALAHHYDDLIDTFIMNLFYNGRLHTFEPVSFLDRSKITVIRPMIYVKEKDIRSE
HCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHEEHHHHHEEHHHHHHH
VKKSNLPVVKNPCPVEGHTKRHYIRNLLIDLKKEIPEIDKRIFTAIKKDVFHFEG
HHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKILGRIRRAVQDFNMIQEGDIIAVGVSGGKDSVTLLYGLHLLKNFYPEKFEVMGLMLT
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHE
LGYDNFDPTPVENFCREKGIPFFIKETDIKKIVFDYRKEENPCSLCANLRRGALNNFAKE
ECCCCCCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KGCNKVALAHHYDDLIDTFIMNLFYNGRLHTFEPVSFLDRSKITVIRPMIYVKEKDIRSE
HCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHEEHHHHHEEHHHHHHH
VKKSNLPVVKNPCPVEGHTKRHYIRNLLIDLKKEIPEIDKRIFTAIKKDVFHFEG
HHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA