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The map label for this gene is ackA [H]

Identifier: 167040368

GI number: 167040368

Start: 1737034

End: 1738239

Strand: Reverse

Name: ackA [H]

Synonym: Teth514_1731

Alternate gene names: 167040368

Gene position: 1738239-1737034 (Counterclockwise)

Preceding gene: 167040369

Following gene: 167040367

Centisome position: 70.74

GC content: 34.33

Gene sequence:

>1206_bases
ATGAAGATTTTGGTTATGAACTGTGGAAGTTCGTCATTAAAGTATCAATTATTGGATATGGATAATGGAAAAGTGCTAGC
GAAAGGATTGGCGGAAAGAATAGGTATCCATGATTCTCTTTTAACTCATCAAGTAGAGGGCAAAGATAAAATAAAGATAC
AAAAAGATATGAAAAATCATAAAGAAGCTATACAAATTGTTTTAGATGCTTTGGTTGATAAAGAAATCGGAATATTAAAG
GATATGAAAGAAATAGATGCAGTAGGACATAGAGTCGTTCATGGTGGAGAGTTTTTTACTGATTCCGTATTGATTGACGA
TGAGGTAATCAAAAAATTAGAAGCATGTATTGACCTTGCACCTTTGCACAATCCTGCTAATATTGAGGGAATAAAAGCTT
GTCGGCAGATAATGCCAGGGGTGCCAATGGTAGCAGTTTTTGATACGGCTTTCCATCAAACAATGCCAGATTATGCGTAT
ATTTATCCCATTCCTTATGAATACTACGAGAAATACAGAATAAGAAGATATGGATTCCATGGGACTTCTCATAAATATGT
ATCTTTAAGAGCTGCTGAAATATTAAAGAGGCCTATTGAAGAGTTAAAAATTATTACTTGCCATTTAGGGAATGGGTCTA
GTATTGCTGCGGTTAAAGGCGGTAAGTCGATAGATACAAGTATGGGATTTACTCCATTAGAAGGGCTGGCTATGGGTACA
AGGTCCGGAAATGTTGATCCTTCAATTATAACTTTCTTAATGGAAAAAGAAGGATTGACTGCAGAACAGGTTATAGATAT
ACTTAATAAGAAATCAGGTGTATACGGAATTTCAGGAATAAGTAATGACTTTAGAGATATAGAAAATGCAGCTTTTAAAG
AAGGGCATAAAAGGGCTATGTTGGCATTAAAAGTTTTCGCTTATAGGGTGAAAAAGACAATAGGTTCTTATACAGCTGCT
ATGGGTGGTGTTGATGTAATTGTGTTTACTGCTGGAGTTGGAGAAAATGGACCAGAAATGAGAGAGTTTATTTTAGAGGA
TCTAGAGTTTTTAGGTTTTAAACTGGACAAAGAGAAGAATAAGGTAAGAGGAAAAGAGGAAATTATATCTACAGAAGATT
CAAAAGTTAAAGTTATGGTTATTCCTACAAATGAAGAATATATGATTGCTAAAGATACTGAAAAATTGGTAAGGGGTTTA
AAGTAG

Upstream 100 bases:

>100_bases
TTGTCAAGAGGTTGTAGTGTAGAAGATATTGTTAATGTTATAGCAATAACTTGTGTACAAGCTCAAGGGGTGCAAAAATA
ACTTTGAGGAGGCAGCGAGT

Downstream 100 bases:

>100_bases
ATAATCTTGACAACGGGTTGTGGGGTTAGTATAATAGGTGATGTCAATTATTTTAAGGTGTGTGAAGAAAAATGAAAGTC
GATCTATTAAAAATCAAAGG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKILVMNCGSSSLKYQLLDMDNGKVLAKGLAERIGIHDSLLTHQVEGKDKIKIQKDMKNHKEAIQIVLDALVDKEIGILK
DMKEIDAVGHRVVHGGEFFTDSVLIDDEVIKKLEACIDLAPLHNPANIEGIKACRQIMPGVPMVAVFDTAFHQTMPDYAY
IYPIPYEYYEKYRIRRYGFHGTSHKYVSLRAAEILKRPIEELKIITCHLGNGSSIAAVKGGKSIDTSMGFTPLEGLAMGT
RSGNVDPSIITFLMEKEGLTAEQVIDILNKKSGVYGISGISNDFRDIENAAFKEGHKRAMLALKVFAYRVKKTIGSYTAA
MGGVDVIVFTAGVGENGPEMREFILEDLEFLGFKLDKEKNKVRGKEEIISTEDSKVKVMVIPTNEEYMIAKDTEKLVRGL
K

Sequences:

>Translated_401_residues
MKILVMNCGSSSLKYQLLDMDNGKVLAKGLAERIGIHDSLLTHQVEGKDKIKIQKDMKNHKEAIQIVLDALVDKEIGILK
DMKEIDAVGHRVVHGGEFFTDSVLIDDEVIKKLEACIDLAPLHNPANIEGIKACRQIMPGVPMVAVFDTAFHQTMPDYAY
IYPIPYEYYEKYRIRRYGFHGTSHKYVSLRAAEILKRPIEELKIITCHLGNGSSIAAVKGGKSIDTSMGFTPLEGLAMGT
RSGNVDPSIITFLMEKEGLTAEQVIDILNKKSGVYGISGISNDFRDIENAAFKEGHKRAMLALKVFAYRVKKTIGSYTAA
MGGVDVIVFTAGVGENGPEMREFILEDLEFLGFKLDKEKNKVRGKEEIISTEDSKVKVMVIPTNEEYMIAKDTEKLVRGL
K
>Mature_401_residues
MKILVMNCGSSSLKYQLLDMDNGKVLAKGLAERIGIHDSLLTHQVEGKDKIKIQKDMKNHKEAIQIVLDALVDKEIGILK
DMKEIDAVGHRVVHGGEFFTDSVLIDDEVIKKLEACIDLAPLHNPANIEGIKACRQIMPGVPMVAVFDTAFHQTMPDYAY
IYPIPYEYYEKYRIRRYGFHGTSHKYVSLRAAEILKRPIEELKIITCHLGNGSSIAAVKGGKSIDTSMGFTPLEGLAMGT
RSGNVDPSIITFLMEKEGLTAEQVIDILNKKSGVYGISGISNDFRDIENAAFKEGHKRAMLALKVFAYRVKKTIGSYTAA
MGGVDVIVFTAGVGENGPEMREFILEDLEFLGFKLDKEKNKVRGKEEIISTEDSKVKVMVIPTNEEYMIAKDTEKLVRGL
K

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=401, Percent_Identity=44.8877805486284, Blast_Score=347, Evalue=5e-97,
Organism=Escherichia coli, GI145693184, Length=396, Percent_Identity=43.1818181818182, Blast_Score=342, Evalue=3e-95,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 44607; Mature: 44607

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVMNCGSSSLKYQLLDMDNGKVLAKGLAERIGIHDSLLTHQVEGKDKIKIQKDMKNH
CEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEHHHHHHH
KEAIQIVLDALVDKEIGILKDMKEIDAVGHRVVHGGEFFTDSVLIDDEVIKKLEACIDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEECCEEECHHHHHHHHHHHHHH
PLHNPANIEGIKACRQIMPGVPMVAVFDTAFHQTMPDYAYIYPIPYEYYEKYRIRRYGFH
CCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHEECCC
GTSHKYVSLRAAEILKRPIEELKIITCHLGNGSSIAAVKGGKSIDTSMGFTPLEGLAMGT
CCCCCEEEHHHHHHHHCCHHHEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHEECC
RSGNVDPSIITFLMEKEGLTAEQVIDILNKKSGVYGISGISNDFRDIENAAFKEGHKRAM
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
LALKVFAYRVKKTIGSYTAAMGGVDVIVFTAGVGENGPEMREFILEDLEFLGFKLDKEKN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEECCHHH
KVRGKEEIISTEDSKVKVMVIPTNEEYMIAKDTEKLVRGLK
HCCCHHHHHCCCCCEEEEEEEECCCCEEEECCHHHHHCCCC
>Mature Secondary Structure
MKILVMNCGSSSLKYQLLDMDNGKVLAKGLAERIGIHDSLLTHQVEGKDKIKIQKDMKNH
CEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEHHHHHHH
KEAIQIVLDALVDKEIGILKDMKEIDAVGHRVVHGGEFFTDSVLIDDEVIKKLEACIDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEECCEEECHHHHHHHHHHHHHH
PLHNPANIEGIKACRQIMPGVPMVAVFDTAFHQTMPDYAYIYPIPYEYYEKYRIRRYGFH
CCCCCCCCHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHEECCC
GTSHKYVSLRAAEILKRPIEELKIITCHLGNGSSIAAVKGGKSIDTSMGFTPLEGLAMGT
CCCCCEEEHHHHHHHHCCHHHEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHEECC
RSGNVDPSIITFLMEKEGLTAEQVIDILNKKSGVYGISGISNDFRDIENAAFKEGHKRAM
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
LALKVFAYRVKKTIGSYTAAMGGVDVIVFTAGVGENGPEMREFILEDLEFLGFKLDKEKN
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCEEECCHHH
KVRGKEEIISTEDSKVKVMVIPTNEEYMIAKDTEKLVRGLK
HCCCHHHHHCCCCCEEEEEEEECCCCEEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA