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The map label for this gene is fabF [H]

Identifier: 167040358

GI number: 167040358

Start: 1729383

End: 1730612

Strand: Reverse

Name: fabF [H]

Synonym: Teth514_1721

Alternate gene names: 167040358

Gene position: 1730612-1729383 (Counterclockwise)

Preceding gene: 167040359

Following gene: 167040357

Centisome position: 70.43

GC content: 37.64

Gene sequence:

>1230_bases
ATGAACAGAGTAGTTGTAACGGGAGTAGGAGTCATTACACCTTTAGGTAATACTGTAGAAAAATTTTGGAATTCTTTAAT
AAATGGTGAGTCTGGAATAGACACTGTTACCAAATTTGACGTGTCTGAGTTTCCTACTAAGGTAGCAGCAGAAGTAAAAG
ATTTTGAACCCACTTTATACATAGACAAAAAAGAAGCAAGAAGAATGGATAGGTTCATCCAGTTTGCTGTTGCCAGCGCG
AAGTTGGCATTAGAGGATTCACAAATTGACCTTTCTAAAGTTGATTTAAACAGGTTTGGGGTCATTTACGGTACAGGCAT
AGGAGGAATTGAAACTTTTGAGAATCAGTTGAAAATTATGCATGAAAAAGGTCCCGGAAAAGTAAGTCCCTTTTTCATCC
CTATGATGATAGCAAATATGGCAGCAGGTCAAATTGCAATAACTTTTGGGCTAAAAGGGATAAACGAGACTATAGTAAAT
GCCTGTGCTTCCAGTACTAATGCTATAGGAGAAGCTTTTAAAGCTATTCAACGGGGAGATGCAGACCTTATAGTTACAGG
TGGTACTGAAGCCGCTATAACTCCTATGTCTTTTGCAGGCTTTTGTGCAATGAAAGCTATGTCCACAAATGAGGACCCTA
AAAAAGCCTCCCGTCCTTTTGACTTAAATAGAGATGGTTTTGTAATGGGAGAAGGGTCTGCAAGCTTAATTTTAGAATCT
TTAGAACATGCACAAAAAAGAGGAGCTAAAATTTATGCAGAGATAATAGGTTATGGTGCTACAGATGATGCTTACCACAT
AACTGCTCCTGCGCCAGAAGGAGAAGGAGCTGCTCGTGCAATGGAAGCAGCTTTAAAGGACGGAAAAGTAAGTTTTGACA
TGATAGATTATATCAATGCTCATGGAACTTCCACTGAATATAACGACAAATTTGAAACAATGGCTATAAAGAAGGTCTTT
AAAGACCATGCGTATAAACTCTATGTAAGTTCTATCAAGTCTATGGTAGGCCATTTATTAGGAGCAGCAGGGGCGATAGA
AGCTGTTGCTACTGTTTTGACTATAAAAAATGGCATTATACCTCCTACTATTAATTACGAAACTCCTGATCCAGAGTGCG
ATTTGAATTATGTGCCTAACAAGGCTATAGAAAAAGAAGTAAATTATGCGATTTCTAATTCCTTTGGCTTTGGAGGACAT
AATGGGACATTACTTTTTAAAAAATTTTAA

Upstream 100 bases:

>100_bases
TGATGTAGTAGAATACTTAAGCAATCTTGAATAATTGAGGTCCCGCGTTGCGGGACTTTATGCAATATAAAATTTTACTC
TATTTTGGAGGTTTTAACCG

Downstream 100 bases:

>100_bases
AAGAGGTATGGAAGTGAAAAGAGAAAATTTGTCTGAATTAGAGGAGAGAATAAATTATAGTTTTAAAGATAAAAATTTGC
TTATAGAGGCTTTAACTCAC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MNRVVVTGVGVITPLGNTVEKFWNSLINGESGIDTVTKFDVSEFPTKVAAEVKDFEPTLYIDKKEARRMDRFIQFAVASA
KLALEDSQIDLSKVDLNRFGVIYGTGIGGIETFENQLKIMHEKGPGKVSPFFIPMMIANMAAGQIAITFGLKGINETIVN
ACASSTNAIGEAFKAIQRGDADLIVTGGTEAAITPMSFAGFCAMKAMSTNEDPKKASRPFDLNRDGFVMGEGSASLILES
LEHAQKRGAKIYAEIIGYGATDDAYHITAPAPEGEGAARAMEAALKDGKVSFDMIDYINAHGTSTEYNDKFETMAIKKVF
KDHAYKLYVSSIKSMVGHLLGAAGAIEAVATVLTIKNGIIPPTINYETPDPECDLNYVPNKAIEKEVNYAISNSFGFGGH
NGTLLFKKF

Sequences:

>Translated_409_residues
MNRVVVTGVGVITPLGNTVEKFWNSLINGESGIDTVTKFDVSEFPTKVAAEVKDFEPTLYIDKKEARRMDRFIQFAVASA
KLALEDSQIDLSKVDLNRFGVIYGTGIGGIETFENQLKIMHEKGPGKVSPFFIPMMIANMAAGQIAITFGLKGINETIVN
ACASSTNAIGEAFKAIQRGDADLIVTGGTEAAITPMSFAGFCAMKAMSTNEDPKKASRPFDLNRDGFVMGEGSASLILES
LEHAQKRGAKIYAEIIGYGATDDAYHITAPAPEGEGAARAMEAALKDGKVSFDMIDYINAHGTSTEYNDKFETMAIKKVF
KDHAYKLYVSSIKSMVGHLLGAAGAIEAVATVLTIKNGIIPPTINYETPDPECDLNYVPNKAIEKEVNYAISNSFGFGGH
NGTLLFKKF
>Mature_409_residues
MNRVVVTGVGVITPLGNTVEKFWNSLINGESGIDTVTKFDVSEFPTKVAAEVKDFEPTLYIDKKEARRMDRFIQFAVASA
KLALEDSQIDLSKVDLNRFGVIYGTGIGGIETFENQLKIMHEKGPGKVSPFFIPMMIANMAAGQIAITFGLKGINETIVN
ACASSTNAIGEAFKAIQRGDADLIVTGGTEAAITPMSFAGFCAMKAMSTNEDPKKASRPFDLNRDGFVMGEGSASLILES
LEHAQKRGAKIYAEIIGYGATDDAYHITAPAPEGEGAARAMEAALKDGKVSFDMIDYINAHGTSTEYNDKFETMAIKKVF
KDHAYKLYVSSIKSMVGHLLGAAGAIEAVATVLTIKNGIIPPTINYETPDPECDLNYVPNKAIEKEVNYAISNSFGFGGH
NGTLLFKKF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=413, Percent_Identity=48.18401937046, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI223972627, Length=182, Percent_Identity=50.5494505494505, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI41872631, Length=425, Percent_Identity=24.2352941176471, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=48.0487804878049, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1788663, Length=414, Percent_Identity=37.9227053140097, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=36.5384615384615, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=39.3939393939394, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI212642053, Length=427, Percent_Identity=25.2927400468384, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=275, Percent_Identity=28.7272727272727, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=443, Percent_Identity=37.2460496613996, Blast_Score=304, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=42.2802850356295, Blast_Score=334, Evalue=8e-92,
Organism=Drosophila melanogaster, GI221330659, Length=425, Percent_Identity=24, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19920632, Length=425, Percent_Identity=24, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24581345, Length=428, Percent_Identity=23.5981308411215, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44079; Mature: 44079

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVVVTGVGVITPLGNTVEKFWNSLINGESGIDTVTKFDVSEFPTKVAAEVKDFEPTLY
CCCEEEECCEEECCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHCCHHHHHHHHCCCCEEE
IDKKEARRMDRFIQFAVASAKLALEDSQIDLSKVDLNRFGVIYGTGIGGIETFENQLKIM
ECHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEECHHHCEEEEECCCCCHHHHHHHHHEE
HEKGPGKVSPFFIPMMIANMAAGQIAITFGLKGINETIVNACASSTNAIGEAFKAIQRGD
ECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
ADLIVTGGTEAAITPMSFAGFCAMKAMSTNEDPKKASRPFDLNRDGFVMGEGSASLILES
CCEEEECCCCCEECCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCHHHHHHHH
LEHAQKRGAKIYAEIIGYGATDDAYHITAPAPEGEGAARAMEAALKDGKVSFDMIDYINA
HHHHHHCCCEEEEHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHC
HGTSTEYNDKFETMAIKKVFKDHAYKLYVSSIKSMVGHLLGAAGAIEAVATVLTIKNGII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
PPTINYETPDPECDLNYVPNKAIEKEVNYAISNSFGFGGHNGTLLFKKF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MNRVVVTGVGVITPLGNTVEKFWNSLINGESGIDTVTKFDVSEFPTKVAAEVKDFEPTLY
CCCEEEECCEEECCCCHHHHHHHHHHHCCCCCCCHHHCCCHHHCCHHHHHHHHCCCCEEE
IDKKEARRMDRFIQFAVASAKLALEDSQIDLSKVDLNRFGVIYGTGIGGIETFENQLKIM
ECHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEECHHHCEEEEECCCCCHHHHHHHHHEE
HEKGPGKVSPFFIPMMIANMAAGQIAITFGLKGINETIVNACASSTNAIGEAFKAIQRGD
ECCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHCCC
ADLIVTGGTEAAITPMSFAGFCAMKAMSTNEDPKKASRPFDLNRDGFVMGEGSASLILES
CCEEEECCCCCEECCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCEEEECCHHHHHHHH
LEHAQKRGAKIYAEIIGYGATDDAYHITAPAPEGEGAARAMEAALKDGKVSFDMIDYINA
HHHHHHCCCEEEEHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCEEHHHHHHHC
HGTSTEYNDKFETMAIKKVFKDHAYKLYVSSIKSMVGHLLGAAGAIEAVATVLTIKNGII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
PPTINYETPDPECDLNYVPNKAIEKEVNYAISNSFGFGGHNGTLLFKKF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]