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The map label for this gene is hfq

Identifier: 167040251

GI number: 167040251

Start: 1632247

End: 1632507

Strand: Direct

Name: hfq

Synonym: Teth514_1614

Alternate gene names: 167040251

Gene position: 1632247-1632507 (Clockwise)

Preceding gene: 167040250

Following gene: 167040252

Centisome position: 66.43

GC content: 35.25

Gene sequence:

>261_bases
ATGGCAAGTTCAAAAGCAGCTATTAATTTACAGGATATCTTTTTAAATCAAGTGAGGAAAGAGCATGTACCAGTAACTGT
CTACTTAATCAACGGATTTCAATTAAAGGGTTTAGTGAAAGGATTTGATAATTTTACAGTGGTGTTGGAGTCAGAGAACA
AACAGCAACTTCTTATCTACAAACATGCTATTTCGACAATTACACCTCAAAAGCCTGTGATCTTCTCTGCTTCTGATAAA
GATGAGAAGAGAGAAGAGTGA

Upstream 100 bases:

>100_bases
TTATGAAGAACTCAAGAAAAATATTATTAAATATTTAGCAGGAAAATTAAATTTTTGATAGAATATAACTAATGATACAT
ATTAAAGAAGGGGGATAAAG

Downstream 100 bases:

>100_bases
AAAAAACAAAAAAACAGTATTAGGGCAACTAATACTGTTTTTTTGAAATAATAAAGTAAGGGAGTTTGCCAAAATGAAGA
TTGGTTTCATAGGTGTTGGC

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 85

Protein sequence:

>86_residues
MASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGLVKGFDNFTVVLESENKQQLLIYKHAISTITPQKPVIFSASDK
DEKREE

Sequences:

>Translated_86_residues
MASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGLVKGFDNFTVVLESENKQQLLIYKHAISTITPQKPVIFSASDK
DEKREE
>Mature_85_residues
ASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGLVKGFDNFTVVLESENKQQLLIYKHAISTITPQKPVIFSASDKD
EKREE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=65, Percent_Identity=49.2307692307692, Blast_Score=76, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_THEP3 (B0K9L8)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665167.1
- ProteinModelPortal:   B0K9L8
- SMR:   B0K9L8
- GeneID:   5875251
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1177
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- ProtClustDB:   CLSK901193
- BioCyc:   TPSE340099:TETH39_1177-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9761; Mature: 9630

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGLVKGFDNFTVVLESENKQQLLIY
CCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCCEEEEE
KHAISTITPQKPVIFSASDKDEKREE
EEEHHCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
ASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGLVKGFDNFTVVLESENKQQLLIY
CCCCCEEEHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCCEEEEE
KHAISTITPQKPVIFSASDKDEKREE
EEEHHCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA