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The map label for this gene is speH

Identifier: 167040245

GI number: 167040245

Start: 1624065

End: 1624439

Strand: Direct

Name: speH

Synonym: Teth514_1608

Alternate gene names: 167040245

Gene position: 1624065-1624439 (Clockwise)

Preceding gene: 167040244

Following gene: 167040246

Centisome position: 66.09

GC content: 41.87

Gene sequence:

>375_bases
ATGAATGCTTTGGGTCGCCACATTTTGGCAGAAATTTATGGGTGCGATAGCAATATTTTAGACAACTTGGAATTAATCGA
AGACATAATGGTTCAGTCTGCAATAGTGACAGGCGCAGAGATACGGGAAGTAGCTTTCCATAAATTTAATCCCCAGGGCG
TAAGCGGAGTAGTGGTCATATCAGAATCTCATATAACTATCCATACTTGGCCAGAACTGGGTTATGCCGCGGTTGACGTA
TTTACTTGTGGTGATGATGTCAATCCGTGGGATGCCTGTAACTATATAGCGAAAATGTTAAGAGCACAAAACATGACTGC
AACAGAGGTGAAACGTGGAGTATTTGAAAAACCAGTGAAGGTGGTTAACTACTGA

Upstream 100 bases:

>100_bases
TTAAACTGTCATGTAAAAAACCTTGACAAAAGAAAAAAATCTGATAAAATTAAAATCATTGAATGTATACATTATTTTAG
TAAAGGAGGCACGATACAAA

Downstream 100 bases:

>100_bases
TTAAATTCCATAGTATGAAGGTTTTGATTCCTTTGTGGCTTTTAAAGCCACTTTTTTCTATAATTAGGGGTGAACATATT
TATGGTAGGTTATGAGGACT

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MNALGRHILAEIYGCDSNILDNLELIEDIMVQSAIVTGAEIREVAFHKFNPQGVSGVVVISESHITIHTWPELGYAAVDV
FTCGDDVNPWDACNYIAKMLRAQNMTATEVKRGVFEKPVKVVNY

Sequences:

>Translated_124_residues
MNALGRHILAEIYGCDSNILDNLELIEDIMVQSAIVTGAEIREVAFHKFNPQGVSGVVVISESHITIHTWPELGYAAVDV
FTCGDDVNPWDACNYIAKMLRAQNMTATEVKRGVFEKPVKVVNY
>Mature_124_residues
MNALGRHILAEIYGCDSNILDNLELIEDIMVQSAIVTGAEIREVAFHKFNPQGVSGVVVISESHITIHTWPELGYAAVDV
FTCGDDVNPWDACNYIAKMLRAQNMTATEVKRGVFEKPVKVVNY

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_THEP3 (B0K9L2)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001665161.1
- ProteinModelPortal:   B0K9L2
- SMR:   B0K9L2
- GeneID:   5875254
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_1171
- HOGENOM:   HBG485559
- OMA:   VEAAGCD
- ProtClustDB:   PRK03124
- BioCyc:   TPSE340099:TETH39_1171-MONOMER
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 13738; Mature: 13738

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALGRHILAEIYGCDSNILDNLELIEDIMVQSAIVTGAEIREVAFHKFNPQGVSGVVVI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHITIHTWPELGYAAVDVFTCGDDVNPWDACNYIAKMLRAQNMTATEVKRGVFEKPVK
ECCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
VVNY
HCCC
>Mature Secondary Structure
MNALGRHILAEIYGCDSNILDNLELIEDIMVQSAIVTGAEIREVAFHKFNPQGVSGVVVI
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEE
SESHITIHTWPELGYAAVDVFTCGDDVNPWDACNYIAKMLRAQNMTATEVKRGVFEKPVK
ECCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHH
VVNY
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA