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The map label for this gene is speA [H]

Identifier: 167040077

GI number: 167040077

Start: 1470126

End: 1471613

Strand: Reverse

Name: speA [H]

Synonym: Teth514_1437

Alternate gene names: 167040077

Gene position: 1471613-1470126 (Counterclockwise)

Preceding gene: 167040082

Following gene: 167040071

Centisome position: 59.89

GC content: 36.36

Gene sequence:

>1488_bases
TTGAAAAAGTTAGATCAAACCCAAACTCCTTTATTTGATGCCTTAATGGAATATGTAAATAACAATACTATCCCTTTTCA
CGTGCCAGGCCATAAAAAAGGTGTGGGAATGGCAAAAAAGTTCTTAGACTTTGTGGGCAAAAATGTATTGTCAATGGATG
TAACAGTGTTTCAGCAAGTAGACAGCTTGCACAAACCTACTGGACCAATTAAGTATGCCCAAGAATTAGCAGCAGAAGCT
TTTGGTGCCGACGCTACCTTTTTCTCTATACACGGAACATCTGGTGCAATTCAAGCAATGATTTTAAGTGTAATGGGAGA
AGAAGAAAAAATTATCGTTCCTCGAAATATTCATAAATCTGTAACGTCAGGAATTATATTAAGTGGTGCTATACCTGTTT
ATATGCAACCAGAAATTGATAAAAATATCGGTGTTGCATTAAATGTCACCCCAGAAACAGTAGAAAGAGCGTTAAGAGAA
CATCCCGATGCAAAAGCTGTTTTAATAATAAACCCGACTTATTACGGAGTTTCTACGGATATAGTAAAAATTGCTGAAAT
TGTTCATGATTATGGCGCTATACTCATGGTGGATGAAGCTCACGGACCACACCTTAAATTTAACGAAAAATTGCCTATTT
CAGCGATGGAAGCAGGAGCCGATATCTGTGCACAGAGCACTCATAAGATTATTGGCTCAATGACGCAGAGCTCGATGCTT
CACGTTAAAGGCGATAGAATTGATATTAATAGAGTAAAACAAGTAATGAGTTTACTCCAGACAACAAGTCCTTCATATAT
ATTGTTGGCTTCCTTAGATGTTGCAAGAATGCAAATGGCTACAGAAGGAAGAGAATTATTAGATAAAACAATAGAATTAG
CAGAGTACGCTCGAAAAGAGATAAACAATATAAAAGGACTCTACTGTTTTGGTGAAGAAATTGTTGGCCGAGATGGTGCC
TATGACTTTGACCCCACAAAAGTTACAATAACAGCTAAAGGCCTTGGAATAAGCGGCCATCAGTTAGAGAAAATATTGGC
AGAAAGATATTATATACAACCTGAACTATCAGATATGTATAATGTTTTATGTGTATTCTCTATTGGTGATACAAAGGAAA
AAGTCGATTATCTCTTAAGGGCTTTAAGAGAAATAAGCGATGAATTATACAATGAAAACATTGAAATAGCGAAACCTATA
GATATACCAGAAATACCAGAACAAGTAGTATCACCAAGATATGCTTTTGGCTCCTCCACTGTTGCACTACCTTTAAGAGA
AAGTGTAGGGCAAATAAGTGCCGAGTTTTTGATGGCTTATCCTCCAGGTATTCCAGTGCTTTGCCCAGGGGAAAGAATAA
CATTAAAAATTATAGAATATGTAGATAAAATGAAAGAAGCTAACTTAAGCATACAAGGCACCGAAGACCCGGAAGTAAAT
TATATAAAAGTAGTAAATGACCGGCAAGTTTTAAACGTGATAGCATAA

Upstream 100 bases:

>100_bases
AGCAGCGATGCTCTGCAAAGCCTATACCTTTGAATTACTTATATCAAGGTTTTAGGCTTTTATTCTGAGCCAAAACTTAT
GAAAGAAGGTGTTAGATGCG

Downstream 100 bases:

>100_bases
TGTTTTACTAAAAAAGGAGTATCTTTCACAAAAAGATACTCCTTTTTTAGTAGCTATTTTAAATATTTTGACAGCTTTTC
AACTAAATGCTCTTTAGGCA

Product: Orn/Lys/Arg decarboxylase, major region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGVGMAKKFLDFVGKNVLSMDVTVFQQVDSLHKPTGPIKYAQELAAEA
FGADATFFSIHGTSGAIQAMILSVMGEEEKIIVPRNIHKSVTSGIILSGAIPVYMQPEIDKNIGVALNVTPETVERALRE
HPDAKAVLIINPTYYGVSTDIVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGRELLDKTIELAEYARKEINNIKGLYCFGEEIVGRDGA
YDFDPTKVTITAKGLGISGHQLEKILAERYYIQPELSDMYNVLCVFSIGDTKEKVDYLLRALREISDELYNENIEIAKPI
DIPEIPEQVVSPRYAFGSSTVALPLRESVGQISAEFLMAYPPGIPVLCPGERITLKIIEYVDKMKEANLSIQGTEDPEVN
YIKVVNDRQVLNVIA

Sequences:

>Translated_495_residues
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGVGMAKKFLDFVGKNVLSMDVTVFQQVDSLHKPTGPIKYAQELAAEA
FGADATFFSIHGTSGAIQAMILSVMGEEEKIIVPRNIHKSVTSGIILSGAIPVYMQPEIDKNIGVALNVTPETVERALRE
HPDAKAVLIINPTYYGVSTDIVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGRELLDKTIELAEYARKEINNIKGLYCFGEEIVGRDGA
YDFDPTKVTITAKGLGISGHQLEKILAERYYIQPELSDMYNVLCVFSIGDTKEKVDYLLRALREISDELYNENIEIAKPI
DIPEIPEQVVSPRYAFGSSTVALPLRESVGQISAEFLMAYPPGIPVLCPGERITLKIIEYVDKMKEANLSIQGTEDPEVN
YIKVVNDRQVLNVIA
>Mature_495_residues
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGVGMAKKFLDFVGKNVLSMDVTVFQQVDSLHKPTGPIKYAQELAAEA
FGADATFFSIHGTSGAIQAMILSVMGEEEKIIVPRNIHKSVTSGIILSGAIPVYMQPEIDKNIGVALNVTPETVERALRE
HPDAKAVLIINPTYYGVSTDIVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGRELLDKTIELAEYARKEINNIKGLYCFGEEIVGRDGA
YDFDPTKVTITAKGLGISGHQLEKILAERYYIQPELSDMYNVLCVFSIGDTKEKVDYLLRALREISDELYNENIEIAKPI
DIPEIPEQVVSPRYAFGSSTVALPLRESVGQISAEFLMAYPPGIPVLCPGERITLKIIEYVDKMKEANLSIQGTEDPEVN
YIKVVNDRQVLNVIA

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=569, Percent_Identity=27.9437609841828, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786384, Length=552, Percent_Identity=27.1739130434783, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI221142684, Length=602, Percent_Identity=26.0797342192691, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI87082193, Length=390, Percent_Identity=27.4358974358974, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786909, Length=394, Percent_Identity=23.3502538071066, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54724; Mature: 54724

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGVGMAKKFLDFVGKNVLSMDVTVFQQV
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
DSLHKPTGPIKYAQELAAEAFGADATFFSIHGTSGAIQAMILSVMGEEEKIIVPRNIHKS
HHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHH
VTSGIILSGAIPVYMQPEIDKNIGVALNVTPETVERALREHPDAKAVLIINPTYYGVSTD
HHCCEEEECCCCEEECCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
IVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCEE
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGRELLDKTIELAEYARKE
EEECCEECHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INNIKGLYCFGEEIVGRDGAYDFDPTKVTITAKGLGISGHQLEKILAERYYIQPELSDMY
HCCCCEEEEECHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHC
NVLCVFSIGDTKEKVDYLLRALREISDELYNENIEIAKPIDIPEIPEQVVSPRYAFGSST
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHCCCCEECCCCE
VALPLRESVGQISAEFLMAYPPGIPVLCPGERITLKIIEYVDKMKEANLSIQGTEDPEVN
EEEEHHHHHHHHHHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCC
YIKVVNDRQVLNVIA
EEEEECCCHHHHHCC
>Mature Secondary Structure
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGVGMAKKFLDFVGKNVLSMDVTVFQQV
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
DSLHKPTGPIKYAQELAAEAFGADATFFSIHGTSGAIQAMILSVMGEEEKIIVPRNIHKS
HHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHH
VTSGIILSGAIPVYMQPEIDKNIGVALNVTPETVERALREHPDAKAVLIINPTYYGVSTD
HHCCEEEECCCCEEECCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
IVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCEE
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGRELLDKTIELAEYARKE
EEECCEECHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INNIKGLYCFGEEIVGRDGAYDFDPTKVTITAKGLGISGHQLEKILAERYYIQPELSDMY
HCCCCEEEEECHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCHHHHC
NVLCVFSIGDTKEKVDYLLRALREISDELYNENIEIAKPIDIPEIPEQVVSPRYAFGSST
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHCCCCEECCCCE
VALPLRESVGQISAEFLMAYPPGIPVLCPGERITLKIIEYVDKMKEANLSIQGTEDPEVN
EEEEHHHHHHHHHHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCC
YIKVVNDRQVLNVIA
EEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]