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The map label for this gene is sdaAA [H]

Identifier: 167040061

GI number: 167040061

Start: 1455332

End: 1456225

Strand: Direct

Name: sdaAA [H]

Synonym: Teth514_1421

Alternate gene names: 167040061

Gene position: 1455332-1456225 (Clockwise)

Preceding gene: 167040060

Following gene: 167040062

Centisome position: 59.23

GC content: 39.6

Gene sequence:

>894_bases
ATGTATCAATTTAATCATGGTTATGAACTATTAGAACTTACAAAAAAATTTAACTTACCAATATCGCAAATTGTGGTGCT
AGCGGAGCAAGAAAAGACAGGAGAAGGCCTTGATACAATTTTTCAAAAGATGAGAAATAACCTCAAAGTAATGAAAGAAG
CTATTAATAAAGGTTTAAATGAAGATTTAAAATCAGTAAGTGGTTTATCAGGTGGAGATGCAAAAAAACTATATGAAAGA
ATAATCATTGGCAATACTCTTTCTTGTGAAACAATGGCAAAAGCTGCTGCTTCTGCTCTTGCAGTGACAGAAGTAAATGC
TTCTATGGGTAAAATTGTTGCTGCTCCTACTGCAGGTTCCAGTGGAGTTATTCCGGGAGCTCTTATTACAGTGGCGAGAA
AATTTGGCAAAAGTGATGATGATATGACAAGAGCTCTTTTCACTGCTACCGGCATAGGTATTATAATAGCTAAAAATGCT
ACTTTATCTGGAGCTGAGGGGGGATGTCAAGCAGAAGTAGGTTCTGCTTCAGCGATGGCTGCAGCAGCTTTAGTAGAACT
TATGGGGGGAACACCAGAACAGTGTTTGACGGCAGCTTCTTTTGCTATAATGAATTTGCTAGGGCTTGTATGCGACCCAG
TTGCAGGGTTGGTAGAAATCCCTTGTGAAAAGAGAAATGCCCTTGGGGCGCTTAATGCTATGATATGCGCTGATTTTGCA
ATAGCAGGAATGGACAGTGTCATACCCTTTGACGAAGTGGTAGAAGCTTTGTATAAAGTAGGAAAAGCCATACCTTACGC
TTTAAGGGAAACTGCAGAAGGGGGACTTGCAAAGACTCCTACAGGGATAAGGCTTAAAAAAGAGATATTTGAAAAAGTTG
AACGGGGGGATTAA

Upstream 100 bases:

>100_bases
CCTATGTAATGGAGCCATGAGATGCTCTTGTTGTGATGAGAAAATTAAAGAAAAACTAAGATATTAAGAGAAAATAAAAG
ATAATAGTGGGAGGTATAAA

Downstream 100 bases:

>100_bases
AGTGGAGGTTTTAAAAGATAGAAGCGAAATTGAAGATAAGTATAAATGGCGACTTGAGGATATATATGAAAATGAGAATT
TGTGGGAAGAAGACTATAAC

Product: L-serine dehydratase, iron-sulfur-dependent subunit alpha

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MYQFNHGYELLELTKKFNLPISQIVVLAEQEKTGEGLDTIFQKMRNNLKVMKEAINKGLNEDLKSVSGLSGGDAKKLYER
IIIGNTLSCETMAKAAASALAVTEVNASMGKIVAAPTAGSSGVIPGALITVARKFGKSDDDMTRALFTATGIGIIIAKNA
TLSGAEGGCQAEVGSASAMAAAALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
IAGMDSVIPFDEVVEALYKVGKAIPYALRETAEGGLAKTPTGIRLKKEIFEKVERGD

Sequences:

>Translated_297_residues
MYQFNHGYELLELTKKFNLPISQIVVLAEQEKTGEGLDTIFQKMRNNLKVMKEAINKGLNEDLKSVSGLSGGDAKKLYER
IIIGNTLSCETMAKAAASALAVTEVNASMGKIVAAPTAGSSGVIPGALITVARKFGKSDDDMTRALFTATGIGIIIAKNA
TLSGAEGGCQAEVGSASAMAAAALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
IAGMDSVIPFDEVVEALYKVGKAIPYALRETAEGGLAKTPTGIRLKKEIFEKVERGD
>Mature_297_residues
MYQFNHGYELLELTKKFNLPISQIVVLAEQEKTGEGLDTIFQKMRNNLKVMKEAINKGLNEDLKSVSGLSGGDAKKLYER
IIIGNTLSCETMAKAAASALAVTEVNASMGKIVAAPTAGSSGVIPGALITVARKFGKSDDDMTRALFTATGIGIIIAKNA
TLSGAEGGCQAEVGSASAMAAAALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
IAGMDSVIPFDEVVEALYKVGKAIPYALRETAEGGLAKTPTGIRLKKEIFEKVERGD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=289, Percent_Identity=35.9861591695502, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788116, Length=289, Percent_Identity=35.2941176470588, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789161, Length=288, Percent_Identity=34.7222222222222, Blast_Score=144, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 31051; Mature: 31051

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQFNHGYELLELTKKFNLPISQIVVLAEQEKTGEGLDTIFQKMRNNLKVMKEAINKGLN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
EDLKSVSGLSGGDAKKLYERIIIGNTLSCETMAKAAASALAVTEVNASMGKIVAAPTAGS
HHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
SGVIPGALITVARKFGKSDDDMTRALFTATGIGIIIAKNATLSGAEGGCQAEVGSASAMA
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHH
AAALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAGMDSVIPFDEVVEALYKVGKAIPYALRETAEGGLAKTPTGIRLKKEIFEKVERGD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQFNHGYELLELTKKFNLPISQIVVLAEQEKTGEGLDTIFQKMRNNLKVMKEAINKGLN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
EDLKSVSGLSGGDAKKLYERIIIGNTLSCETMAKAAASALAVTEVNASMGKIVAAPTAGS
HHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
SGVIPGALITVARKFGKSDDDMTRALFTATGIGIIIAKNATLSGAEGGCQAEVGSASAMA
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHH
AAALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAGMDSVIPFDEVVEALYKVGKAIPYALRETAEGGLAKTPTGIRLKKEIFEKVERGD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]