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The map label for this gene is ansA [H]

Identifier: 167039978

GI number: 167039978

Start: 1373811

End: 1374860

Strand: Reverse

Name: ansA [H]

Synonym: Teth514_1337

Alternate gene names: 167039978

Gene position: 1374860-1373811 (Counterclockwise)

Preceding gene: 167039997

Following gene: 167039967

Centisome position: 55.95

GC content: 34.76

Gene sequence:

>1050_bases
ATGTATTATAATGAAAGTAAGAAAATAAATATTTCTATTACTGTAAATTATTTTTTGGGGGGATTTGCCTTGGAGAAAAT
AGTAATAATTTTTACGGGTGGAACTATATCCATGAAAAATGACCCTAATTTAAATGCTGCTATACCCTCTTTATCAGGAA
AAGACATACTAAAAATGGTTCCCAACATAAAAGAAATTGCCCAAATTGAAATAATCCAATTTGGTAATTCCCCAAGCCCT
CACCTTACTCCTGAGCTATTGGTAAATTTAAGACGAGAAGTTGAAAACGTAATCAAACAACAAGTAAAAGGAGTCGTCAT
TACTCACGGTACAGATACATTAGAGGAAACAGCATATTTTTTAGACTTAACTATAAATTCTGAAAAGCCAATAGTCTTGA
CTGGAGCCATGAAAAATTCTTCTGAAGTTGGATACGACGGTCCCAATAACTTAATTGCTTCTGTAATTACTGCTTCCTCA
GAAAAAGCCAAAAATAAAGGAGTGTTAGTAGTTTTCAATAACGAAATACATGCAGCACGAGATGTCACAAAAACTCATAC
TTCAAGTATTGACACTTTTAAAAGCCTTGAAACAGGTCCAATAGGTGTTGTAGATAATAACAAAGCGTATTTTTATAGGA
ACATTGAGACAAGAAATTATATACCAGTAGACCATTTAGAGCCAAGAGTCAGTCTTCTAAAAGTCGCCTTTGGTATGGAG
GATAAAATTATCAGATTCCTTGTTGATAGCGGAGAAAAAGGAATAGTAATAGAAGGAACAGGAAGGGGAAATGTACCTCC
AAAATTGGCTGAGGGCATAGAATATGCTATATCAAAGGGAGTAATTGTAGTGTTAGTTTCAAGATGTCCTATGGGAAGAG
TTGATGCCTCTTACGGTTATAAAGGTGGCGGAAAGCATCTTGAGTCCTTAGGGGTAATCTTTGGAGGTAATCTCTCAGGG
CAAAAAGCTCGCATAAAACTCATGGCAGCTCTTGCTTATTCCAATAATTACAATGAAATCAAAAAATTATTTGAAGAAGA
AAAGACTTGA

Upstream 100 bases:

>100_bases
TTCATACAGTAACCTCCCTTCTTTTAAAATTTTATGAGGAAGAAATTAAAAAAATTCTCTTGCTTTTTTATAGGTAATAG
ACCTTTTGAGTAATTAGAAA

Downstream 100 bases:

>100_bases
TACCTAATGGCATCAAGTCCTTTGTTTACTGTAGATACTTGTTTACCATGTCTTTAACAAGGTTGCCATCTGCTCTCCCT
TTTACGATTGGCATTACCTT

Product: asparaginase/glutaminase

Products: NA

Alternate protein names: L-ASNase; L-asparagine amidohydrolase [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MYYNESKKINISITVNYFLGGFALEKIVIIFTGGTISMKNDPNLNAAIPSLSGKDILKMVPNIKEIAQIEIIQFGNSPSP
HLTPELLVNLRREVENVIKQQVKGVVITHGTDTLEETAYFLDLTINSEKPIVLTGAMKNSSEVGYDGPNNLIASVITASS
EKAKNKGVLVVFNNEIHAARDVTKTHTSSIDTFKSLETGPIGVVDNNKAYFYRNIETRNYIPVDHLEPRVSLLKVAFGME
DKIIRFLVDSGEKGIVIEGTGRGNVPPKLAEGIEYAISKGVIVVLVSRCPMGRVDASYGYKGGGKHLESLGVIFGGNLSG
QKARIKLMAALAYSNNYNEIKKLFEEEKT

Sequences:

>Translated_349_residues
MYYNESKKINISITVNYFLGGFALEKIVIIFTGGTISMKNDPNLNAAIPSLSGKDILKMVPNIKEIAQIEIIQFGNSPSP
HLTPELLVNLRREVENVIKQQVKGVVITHGTDTLEETAYFLDLTINSEKPIVLTGAMKNSSEVGYDGPNNLIASVITASS
EKAKNKGVLVVFNNEIHAARDVTKTHTSSIDTFKSLETGPIGVVDNNKAYFYRNIETRNYIPVDHLEPRVSLLKVAFGME
DKIIRFLVDSGEKGIVIEGTGRGNVPPKLAEGIEYAISKGVIVVLVSRCPMGRVDASYGYKGGGKHLESLGVIFGGNLSG
QKARIKLMAALAYSNNYNEIKKLFEEEKT
>Mature_349_residues
MYYNESKKINISITVNYFLGGFALEKIVIIFTGGTISMKNDPNLNAAIPSLSGKDILKMVPNIKEIAQIEIIQFGNSPSP
HLTPELLVNLRREVENVIKQQVKGVVITHGTDTLEETAYFLDLTINSEKPIVLTGAMKNSSEVGYDGPNNLIASVITASS
EKAKNKGVLVVFNNEIHAARDVTKTHTSSIDTFKSLETGPIGVVDNNKAYFYRNIETRNYIPVDHLEPRVSLLKVAFGME
DKIIRFLVDSGEKGIVIEGTGRGNVPPKLAEGIEYAISKGVIVVLVSRCPMGRVDASYGYKGGGKHLESLGVIFGGNLSG
QKARIKLMAALAYSNNYNEIKKLFEEEKT

Specific function: Unknown

COG id: COG0252

COG function: function code EJ; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the asparaginase 1 family [H]

Homologues:

Organism=Homo sapiens, GI122937331, Length=206, Percent_Identity=26.6990291262136, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789327, Length=358, Percent_Identity=32.4022346368715, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1788065, Length=343, Percent_Identity=25.0728862973761, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193207372, Length=340, Percent_Identity=25.8823529411765, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17558278, Length=340, Percent_Identity=25.8823529411765, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17558280, Length=340, Percent_Identity=25.8823529411765, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193207374, Length=340, Percent_Identity=25.8823529411765, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6323189, Length=343, Percent_Identity=33.2361516034985, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323187, Length=343, Percent_Identity=33.2361516034985, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323186, Length=343, Percent_Identity=33.2361516034985, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323184, Length=343, Percent_Identity=33.2361516034985, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320527, Length=333, Percent_Identity=32.7327327327327, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645530, Length=237, Percent_Identity=29.535864978903, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24639609, Length=345, Percent_Identity=26.3768115942029, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006034
- InterPro:   IPR020827 [H]

Pfam domain/function: PF00710 Asparaginase [H]

EC number: =3.5.1.1 [H]

Molecular weight: Translated: 38195; Mature: 38195

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00144 ASN_GLN_ASE_1 ; PS00917 ASN_GLN_ASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYNESKKINISITVNYFLGGFALEKIVIIFTGGTISMKNDPNLNAAIPSLSGKDILKMV
CCCCCCEEEEEEEEEEEECCCEEEEEEEEEEECCEEEECCCCCCCEECCCCCCCHHHHHC
PNIKEIAQIEIIQFGNSPSPHLTPELLVNLRREVENVIKQQVKGVVITHGTDTLEETAYF
CCHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHCCEEE
LDLTINSEKPIVLTGAMKNSSEVGYDGPNNLIASVITASSEKAKNKGVLVVFNNEIHAAR
EEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
DVTKTHTSSIDTFKSLETGPIGVVDNNKAYFYRNIETRNYIPVDHLEPRVSLLKVAFGME
HHHHHHCCCHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCH
DKIIRFLVDSGEKGIVIEGTGRGNVPPKLAEGIEYAISKGVIVVLVSRCPMGRVDASYGY
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
KGGGKHLESLGVIFGGNLSGQKARIKLMAALAYSNNYNEIKKLFEEEKT
CCCCHHHHHCCEEECCCCCCCHHEEEEEEEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MYYNESKKINISITVNYFLGGFALEKIVIIFTGGTISMKNDPNLNAAIPSLSGKDILKMV
CCCCCCEEEEEEEEEEEECCCEEEEEEEEEEECCEEEECCCCCCCEECCCCCCCHHHHHC
PNIKEIAQIEIIQFGNSPSPHLTPELLVNLRREVENVIKQQVKGVVITHGTDTLEETAYF
CCHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHCCEEE
LDLTINSEKPIVLTGAMKNSSEVGYDGPNNLIASVITASSEKAKNKGVLVVFNNEIHAAR
EEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
DVTKTHTSSIDTFKSLETGPIGVVDNNKAYFYRNIETRNYIPVDHLEPRVSLLKVAFGME
HHHHHHCCCHHHHHCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCH
DKIIRFLVDSGEKGIVIEGTGRGNVPPKLAEGIEYAISKGVIVVLVSRCPMGRVDASYGY
HHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCC
KGGGKHLESLGVIFGGNLSGQKARIKLMAALAYSNNYNEIKKLFEEEKT
CCCCHHHHHCCEEECCCCCCCHHEEEEEEEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916233 [H]