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The map label for this gene is tpiA [H]

Identifier: 167039951

GI number: 167039951

Start: 1345079

End: 1345825

Strand: Direct

Name: tpiA [H]

Synonym: Teth514_1308

Alternate gene names: 167039951

Gene position: 1345079-1345825 (Clockwise)

Preceding gene: 167039950

Following gene: 167039952

Centisome position: 54.74

GC content: 38.55

Gene sequence:

>747_bases
TTGAGAAGACCAATAATTGCAGGTAATTGGAAAATGCACATGACCCCTTCTGAAGCGGTGAAATTAGTTGATGAATTGAT
ACCTCAAGTGAAAGACGCAAAAGCAGAAGTGGTAGTCATACCTCCCTTTGTGGATTTGACAGAGGTAAATAAAGTAATTC
AAGGTACTAATATTCTTCTCGGAGCACAAGATATGTTTTGGGAAGAAAAGGGCGCATATACGGGGGAAATTTCACCTTTA
ATGCTTAAAGAGATTGGGGTAAAATATGTTGTAATAGGCCACTCTGAAAGAAGGCAGTATTTTGGTGAGACGGATGAAAT
GGTCAATAAAAAAGTTTTATCCGCTCTATCTCACGGCTTAAGTCCTATTGTGTGTGTAGGAGAATCTTTTTCTCAAAGAG
AAGAAGGAAAAACTTTTGAAGTAGTTTTAAGTCAAACTAAAGAGGCTTTAAAAGGCGTTACCCACGATGATATTGTAAAT
GTAGTAATAGCTTATGAGCCAATTTGGGCTATAGGTACTGGCAAAACGGCTACAGCTAAAGACGCCAATGAAGTGATAAA
AGCTATAAGAAATACTATAGCTTCCCTTTATGGAAAAGAAAAAGCAGATCTGGTTAGAATACAATATGGGGGGAGTGTAA
AGCCCGAGAACATCTCTGAACTCATGGCAGAGAGCGATATAGACGGGGCTTTAGTGGGGGGAGCAAGTCTTGTAGCATCA
GATTTTGCAAAGATTGTCAATTATTAA

Upstream 100 bases:

>100_bases
ACTCATATTTCTACTGGAGGAGGAGCTTCTCTAGAGTTTTTGGAAGGCAAAGTGTTGCCGGGAATTGAAGTTTTAAATGA
CAAGTAAAGGGGTGTTTGTT

Downstream 100 bases:

>100_bases
GGAGAGGATTATATGCCTGAAAAATTAACCATGCTAGTTATACTAGATGGGTTTGGACTATCAGTCAAAAAAGAAGGAAA
TGCAGTATATCAAGCTAATA

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRRPIIAGNWKMHMTPSEAVKLVDELIPQVKDAKAEVVVIPPFVDLTEVNKVIQGTNILLGAQDMFWEEKGAYTGEISPL
MLKEIGVKYVVIGHSERRQYFGETDEMVNKKVLSALSHGLSPIVCVGESFSQREEGKTFEVVLSQTKEALKGVTHDDIVN
VVIAYEPIWAIGTGKTATAKDANEVIKAIRNTIASLYGKEKADLVRIQYGGSVKPENISELMAESDIDGALVGGASLVAS
DFAKIVNY

Sequences:

>Translated_248_residues
MRRPIIAGNWKMHMTPSEAVKLVDELIPQVKDAKAEVVVIPPFVDLTEVNKVIQGTNILLGAQDMFWEEKGAYTGEISPL
MLKEIGVKYVVIGHSERRQYFGETDEMVNKKVLSALSHGLSPIVCVGESFSQREEGKTFEVVLSQTKEALKGVTHDDIVN
VVIAYEPIWAIGTGKTATAKDANEVIKAIRNTIASLYGKEKADLVRIQYGGSVKPENISELMAESDIDGALVGGASLVAS
DFAKIVNY
>Mature_248_residues
MRRPIIAGNWKMHMTPSEAVKLVDELIPQVKDAKAEVVVIPPFVDLTEVNKVIQGTNILLGAQDMFWEEKGAYTGEISPL
MLKEIGVKYVVIGHSERRQYFGETDEMVNKKVLSALSHGLSPIVCVGESFSQREEGKTFEVVLSQTKEALKGVTHDDIVN
VVIAYEPIWAIGTGKTATAKDANEVIKAIRNTIASLYGKEKADLVRIQYGGSVKPENISELMAESDIDGALVGGASLVAS
DFAKIVNY

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=246, Percent_Identity=43.0894308943089, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI226529917, Length=246, Percent_Identity=43.0894308943089, Blast_Score=184, Evalue=9e-47,
Organism=Escherichia coli, GI1790353, Length=247, Percent_Identity=45.3441295546559, Blast_Score=203, Evalue=9e-54,
Organism=Caenorhabditis elegans, GI17536593, Length=247, Percent_Identity=42.5101214574899, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320255, Length=246, Percent_Identity=38.6178861788618, Blast_Score=174, Evalue=9e-45,
Organism=Drosophila melanogaster, GI28572008, Length=246, Percent_Identity=43.0894308943089, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28572006, Length=246, Percent_Identity=43.0894308943089, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28572004, Length=246, Percent_Identity=43.0894308943089, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 27078; Mature: 27078

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPIIAGNWKMHMTPSEAVKLVDELIPQVKDAKAEVVVIPPFVDLTEVNKVIQGTNILL
CCCCEEECCCEEEECHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEE
GAQDMFWEEKGAYTGEISPLMLKEIGVKYVVIGHSERRQYFGETDEMVNKKVLSALSHGL
ECHHHHHHHCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHCC
SPIVCVGESFSQREEGKTFEVVLSQTKEALKGVTHDDIVNVVIAYEPIWAIGTGKTATAK
CCEEEECCCHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHEEEEEECCEEEECCCCCCCCC
DANEVIKAIRNTIASLYGKEKADLVRIQYGGSVKPENISELMAESDIDGALVGGASLVAS
CHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECHHHHHHH
DFAKIVNY
HHHHHHCC
>Mature Secondary Structure
MRRPIIAGNWKMHMTPSEAVKLVDELIPQVKDAKAEVVVIPPFVDLTEVNKVIQGTNILL
CCCCEEECCCEEEECHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCEEE
GAQDMFWEEKGAYTGEISPLMLKEIGVKYVVIGHSERRQYFGETDEMVNKKVLSALSHGL
ECHHHHHHHCCCCCCCCCHHHHHHCCEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHCC
SPIVCVGESFSQREEGKTFEVVLSQTKEALKGVTHDDIVNVVIAYEPIWAIGTGKTATAK
CCEEEECCCHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHEEEEEECCEEEECCCCCCCCC
DANEVIKAIRNTIASLYGKEKADLVRIQYGGSVKPENISELMAESDIDGALVGGASLVAS
CHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEECHHHHHHH
DFAKIVNY
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA