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The map label for this gene is pgi [H]

Identifier: 167039853

GI number: 167039853

Start: 1247707

End: 1249062

Strand: Direct

Name: pgi [H]

Synonym: Teth514_1208

Alternate gene names: 167039853

Gene position: 1247707-1249062 (Clockwise)

Preceding gene: 167039850

Following gene: 167039855

Centisome position: 50.78

GC content: 34.14

Gene sequence:

>1356_bases
ATGAGGAAATTGATAAGCTTTGATTATTCAAAAGCGCTGCAATTTGTAAGTGAAAAAGAAATCGAATATATGGAAAGGCA
TGCAAAATTATCTCTTGATATGGTGCTTAGTAAAAATGCTCAAGGAAATGACTTTTTAGGATGGGTGAGTCTTCCCAAAG
ACTATGATAAGGCAGAGTTTGAACGCATTAAAAAAGCAGCAGAGAAGATTAAATCAGATTCTGATGTGCTTGTAGTAATA
GGTATAGGTGGGTCTTATTTAGGGGCAAGAGCGGCAATTGAAATGCTTTCTCATTCCTTCTATAATTTGTTGCCAAAAGG
TAAGAGGAATATGCCGGAGATTTATTTTGCTGGAAACAGCATAAGCTCTACATATTTAAGTGATTTATTTGAACTTATAG
AGGACAAAGATGTATCAATAAATGTGATTTCTAAATCTGGTACTACTACAGAACCGGCAATAGCTTTTAGAGTTTTTAGA
GATTTTCTTGAGAAAAAATATGGAAAAGAAGGGGCTAAATCGAGAATATATGTGACAACAGATAGAGCGAAAGGAGCTTT
AAAAAAATTAGCTGATGAAGAAGGATATGAAACATTTGTGATTCCTGACAATGTTGGAGGAAGATACTCAGTTTTGACAG
CTGTAGGCCTTCTACCAATAGCAGTAGCAGGCATTAGCATAGACGATATGATGCAGGGAGCTTATGATGCTTCAACAGTC
TATACCAAAGACAACCTTAATGAAAATATCAGCATGCAGTATGCAATTTTGAGAAATATTTTGTACAGAAAAGGCAAAGC
TATAGAAATACTTGTAAATTATGAGCCAAAGCTTCACTATTTCTCTGAATGGTGGAAACAGCTTTTTGGAGAAAGTGAAG
GTAAAGACAATAAGGGAATTTATCCTGCTTCAGTAGATTTTACGACAGATTTACACTCAATGGGGCAGTTTATACAAGAG
GGAAGCAGAAATATTTTTGAAACAGTTTTAAATGTTGAAAAACCTGTTAAAGATATAGTTATAAATGAAGACAAGGACAA
TATAGATGGGCTTAACTTTTTAGCAGGAAAAACTATAGATTTTGTCAATAAAAAGGCTTTTGAAGGAACATTATTGGCTC
ATACAGATGGAAATGTTCCTAACCTTGTAGTAAATATCCCTGAAATATCAGCTTACTATTTTGGCAATCTGGTCTACTTC
TTTGAAATGGCTTGTGCTATAAGCGGATATATAAATGGGGTTAATCCATTTGACCAACCAGGAGTAGAGGCTTACAAGAA
AAACATGTTTGCACTTTTAGGAAAACCAGGATATGAAAAAGAAAAAGAATTGTTAGAAAAAAGATTGGGAAAATAA

Upstream 100 bases:

>100_bases
AAAATAAAGCTAAGTAAACTTATACATACTTTTGAAAAACTTGAACAACATAGATTTATGGTATAAAATAAGTATGTAAA
TAAAGAATGGAGGTTTACAT

Downstream 100 bases:

>100_bases
ATTAAAGGCCGGGCAATTGCGCGGCCTTTTTAAATAGGGGTTGACTTATTTTTTTGTGTACATTAAATCGTAGTATTCTT
TTAACATTCTATTAGCTGAG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MRKLISFDYSKALQFVSEKEIEYMERHAKLSLDMVLSKNAQGNDFLGWVSLPKDYDKAEFERIKKAAEKIKSDSDVLVVI
GIGGSYLGARAAIEMLSHSFYNLLPKGKRNMPEIYFAGNSISSTYLSDLFELIEDKDVSINVISKSGTTTEPAIAFRVFR
DFLEKKYGKEGAKSRIYVTTDRAKGALKKLADEEGYETFVIPDNVGGRYSVLTAVGLLPIAVAGISIDDMMQGAYDASTV
YTKDNLNENISMQYAILRNILYRKGKAIEILVNYEPKLHYFSEWWKQLFGESEGKDNKGIYPASVDFTTDLHSMGQFIQE
GSRNIFETVLNVEKPVKDIVINEDKDNIDGLNFLAGKTIDFVNKKAFEGTLLAHTDGNVPNLVVNIPEISAYYFGNLVYF
FEMACAISGYINGVNPFDQPGVEAYKKNMFALLGKPGYEKEKELLEKRLGK

Sequences:

>Translated_451_residues
MRKLISFDYSKALQFVSEKEIEYMERHAKLSLDMVLSKNAQGNDFLGWVSLPKDYDKAEFERIKKAAEKIKSDSDVLVVI
GIGGSYLGARAAIEMLSHSFYNLLPKGKRNMPEIYFAGNSISSTYLSDLFELIEDKDVSINVISKSGTTTEPAIAFRVFR
DFLEKKYGKEGAKSRIYVTTDRAKGALKKLADEEGYETFVIPDNVGGRYSVLTAVGLLPIAVAGISIDDMMQGAYDASTV
YTKDNLNENISMQYAILRNILYRKGKAIEILVNYEPKLHYFSEWWKQLFGESEGKDNKGIYPASVDFTTDLHSMGQFIQE
GSRNIFETVLNVEKPVKDIVINEDKDNIDGLNFLAGKTIDFVNKKAFEGTLLAHTDGNVPNLVVNIPEISAYYFGNLVYF
FEMACAISGYINGVNPFDQPGVEAYKKNMFALLGKPGYEKEKELLEKRLGK
>Mature_451_residues
MRKLISFDYSKALQFVSEKEIEYMERHAKLSLDMVLSKNAQGNDFLGWVSLPKDYDKAEFERIKKAAEKIKSDSDVLVVI
GIGGSYLGARAAIEMLSHSFYNLLPKGKRNMPEIYFAGNSISSTYLSDLFELIEDKDVSINVISKSGTTTEPAIAFRVFR
DFLEKKYGKEGAKSRIYVTTDRAKGALKKLADEEGYETFVIPDNVGGRYSVLTAVGLLPIAVAGISIDDMMQGAYDASTV
YTKDNLNENISMQYAILRNILYRKGKAIEILVNYEPKLHYFSEWWKQLFGESEGKDNKGIYPASVDFTTDLHSMGQFIQE
GSRNIFETVLNVEKPVKDIVINEDKDNIDGLNFLAGKTIDFVNKKAFEGTLLAHTDGNVPNLVVNIPEISAYYFGNLVYF
FEMACAISGYINGVNPFDQPGVEAYKKNMFALLGKPGYEKEKELLEKRLGK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=472, Percent_Identity=23.5169491525424, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790457, Length=438, Percent_Identity=24.6575342465753, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996708, Length=387, Percent_Identity=24.2894056847545, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996703, Length=387, Percent_Identity=24.2894056847545, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319673, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 50670; Mature: 50670

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLISFDYSKALQFVSEKEIEYMERHAKLSLDMVLSKNAQGNDFLGWVSLPKDYDKAEF
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHCEEEHEEECCCCCCCEEEEECCCCCCCHHHH
ERIKKAAEKIKSDSDVLVVIGIGGSYLGARAAIEMLSHSFYNLLPKGKRNMPEIYFAGNS
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
ISSTYLSDLFELIEDKDVSINVISKSGTTTEPAIAFRVFRDFLEKKYGKEGAKSRIYVTT
CHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DRAKGALKKLADEEGYETFVIPDNVGGRYSVLTAVGLLPIAVAGISIDDMMQGAYDASTV
CHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEE
YTKDNLNENISMQYAILRNILYRKGKAIEILVNYEPKLHYFSEWWKQLFGESEGKDNKGI
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
YPASVDFTTDLHSMGQFIQEGSRNIFETVLNVEKPVKDIVINEDKDNIDGLNFLAGKTID
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHEECCCCCCCCCCHHHHCCHHH
FVNKKAFEGTLLAHTDGNVPNLVVNIPEISAYYFGNLVYFFEMACAISGYINGVNPFDQP
HHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GVEAYKKNMFALLGKPGYEKEKELLEKRLGK
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRKLISFDYSKALQFVSEKEIEYMERHAKLSLDMVLSKNAQGNDFLGWVSLPKDYDKAEF
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHCEEEHEEECCCCCCCEEEEECCCCCCCHHHH
ERIKKAAEKIKSDSDVLVVIGIGGSYLGARAAIEMLSHSFYNLLPKGKRNMPEIYFAGNS
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
ISSTYLSDLFELIEDKDVSINVISKSGTTTEPAIAFRVFRDFLEKKYGKEGAKSRIYVTT
CHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
DRAKGALKKLADEEGYETFVIPDNVGGRYSVLTAVGLLPIAVAGISIDDMMQGAYDASTV
CHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEE
YTKDNLNENISMQYAILRNILYRKGKAIEILVNYEPKLHYFSEWWKQLFGESEGKDNKGI
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
YPASVDFTTDLHSMGQFIQEGSRNIFETVLNVEKPVKDIVINEDKDNIDGLNFLAGKTID
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHEECCCCCCCCCCHHHHCCHHH
FVNKKAFEGTLLAHTDGNVPNLVVNIPEISAYYFGNLVYFFEMACAISGYINGVNPFDQP
HHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GVEAYKKNMFALLGKPGYEKEKELLEKRLGK
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA