Click here to switch to the map view.

The map label for this gene is ziaR [H]

Identifier: 167039807

GI number: 167039807

Start: 1198154

End: 1198519

Strand: Direct

Name: ziaR [H]

Synonym: Teth514_1161

Alternate gene names: 167039807

Gene position: 1198154-1198519 (Clockwise)

Preceding gene: 167039803

Following gene: 167039808

Centisome position: 48.76

GC content: 32.51

Gene sequence:

>366_bases
ATGAAAAGAGAAGACAGCAAAATCCCAATCTGCGAAATTAGCGTAATACATGAAGATATTATAAATAAGGTAAAAGAAAC
TATGCCAGAGGAAACAAAATTGTATGACCTTGCAGAATTGTTTAAAGTATTAGGAGATACTACAAGGATAAAAATTCTTT
ATGCATTATTTGAATCAGAAATGTGTGTTTGTGATATTGCTGCACTTCTTGGCATGAGCCAGTCTGCAGTTTCTCATCAG
CTTCGGATACTAAGGCAAAATAAGCTTGTTAAATTTAGAAAAGAAGGAAAAGTGGTTTATTATTCTTTGGCGGATGACCA
TGTAAAGAAAATATTTGAACAGGGTTTTGACCATATTAATGAATGA

Upstream 100 bases:

>100_bases
GTTTTTGGATTAGAGATTGAAGTTCTTGAAAGGAAGCAAAAATTATTATATAATAAAGTATGAACAATTATTCATATATT
AAAGCAAAGAGGAGATGGCC

Downstream 100 bases:

>100_bases
ATCAGGAGAGGTGAATACTATGCAAAATAATAAAAGGGCCTTTGTTTTAGAGAGGTTTGGTTGTAGAAGTTGTGCCCTAG
ATGCAAAAGGAAATCCACTG

Product: regulatory protein ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MKREDSKIPICEISVIHEDIINKVKETMPEETKLYDLAELFKVLGDTTRIKILYALFESEMCVCDIAALLGMSQSAVSHQ
LRILRQNKLVKFRKEGKVVYYSLADDHVKKIFEQGFDHINE

Sequences:

>Translated_121_residues
MKREDSKIPICEISVIHEDIINKVKETMPEETKLYDLAELFKVLGDTTRIKILYALFESEMCVCDIAALLGMSQSAVSHQ
LRILRQNKLVKFRKEGKVVYYSLADDHVKKIFEQGFDHINE
>Mature_121_residues
MKREDSKIPICEISVIHEDIINKVKETMPEETKLYDLAELFKVLGDTTRIKILYALFESEMCVCDIAALLGMSQSAVSHQ
LRILRQNKLVKFRKEGKVVYYSLADDHVKKIFEQGFDHINE

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=67, Percent_Identity=44.7761194029851, Blast_Score=59, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14033; Mature: 14033

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREDSKIPICEISVIHEDIINKVKETMPEETKLYDLAELFKVLGDTTRIKILYALFESE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
MCVCDIAALLGMSQSAVSHQLRILRQNKLVKFRKEGKVVYYSLADDHVKKIFEQGFDHIN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCC
E
C
>Mature Secondary Structure
MKREDSKIPICEISVIHEDIINKVKETMPEETKLYDLAELFKVLGDTTRIKILYALFESE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
MCVCDIAALLGMSQSAVSHQLRILRQNKLVKFRKEGKVVYYSLADDHVKKIFEQGFDHIN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]