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The map label for this gene is ygbD [C]

Identifier: 167039780

GI number: 167039780

Start: 1172508

End: 1173848

Strand: Direct

Name: ygbD [C]

Synonym: Teth514_1131

Alternate gene names: 167039780

Gene position: 1172508-1173848 (Clockwise)

Preceding gene: 167039778

Following gene: 167039781

Centisome position: 47.72

GC content: 35.2

Gene sequence:

>1341_bases
ATGGAAACTGATGTTTTGGTCATTGGAGGAAGTGCAGGTGGAATTTTAGCAGCTTTATCTGCTAAAAAAACTTACAAAGA
TAAGAAAGTAACTGTTGTAAGAATGGGAGAACGGGTAATGGTTCCTTGCGGTATCCCGTACATTTTTGGAACATTAAAAG
ACACATCTAAAAATGTTATACCCGATGCAATGCTTACCAATGCTGGTATTGATTTAATAATAGATGAAGTTCTTTCAATT
GATAGGGAAAACAAGAAAGTTAATGCTAAAAAGAGTGGAGAAATTTCCTACAAAAAACTAATTTTAGCGACAGGTTCTTT
GCCAATAGTTCCTACTTTTATACCAGGGCATGACTTAGAAAATGTATTTACAATAAAAAAAGACGAAGAATACTTAAAAT
TTGTTCAGCAAAAGATTAACGAGGCTCAGGATGTTGTAGTAATTGGCGGTGGATTTATTGGTGTTGAAATGGCAGAGCAG
GTGCAACTTCTTGGCAAAAATGTAACAATAATTGAGGTTGCTGACAAGCTTTTGTGGCAAGCCTTTGACCATGAATACAG
TGATATGGCAGAAGCCACATTAAAAGAACATGGTATAACAATAAAAACAAATACAAAAGTTACAAAACTTGTAGGGGATA
CAAAAGTAAAAGAAGTTGAATTAGATACAGGTGAAAAAATAAAAGCTGACGTTGTCATATTAGCTATGGGCGTAAAACCA
AATACTAAATTAGCTGAAGCTGCAGGTATAAAACTTAATGAAAAAGGAGCAATAACAGTTGATGAATACATGAGAACTAA
CGATCCAGACATATTCGCCGTTGGTGACTGTGCAGAAAAGAAATGCTTCTTTACAAGAAAGAATGTTCCTATACTTCTTG
CCTCTACTGCGGCTAATGAGGCAAAAATTGCAGGTGTAAATGTATTTCAATTAAGATTGGTTAGGGAAAATAAAGGTACA
ATAAGTGCTTTTTCTACAAAGATATACAATACTGCTTTTGCTGCTGCAGGTCTTACAGAAACGCAAGCAAAAGCTGAAGG
CTTTGATATAGTAATCGGAGAATTTAGCACAATGGACAAACATCCTGGAACTTTGCCTAATGCAAAGAGTGTGAAGATAA
AATTGATTTTCTCAAGATATTCTGGAGTCATATTAGGAGCTCAAATAGCAGGAGGAGAAAATGTTGGTGAAATGATTAAT
ATTTTAAGTCTTGCAATACAAAAAGGAACAACAGCGTCAGAACTAAATACATTCCAAGTGGCGACACATCCACTACTCAC
ATCTTCTCCTGTGTCATACCCAATAAATTCAGCTGCTTTAGATGCTATGTCAAAGATATGA

Upstream 100 bases:

>100_bases
TGACATAAGTTTATTATAATCCTATAATTTACGTAGAGGTACCCTACAGGGTAGGGGGTAGTTTCTAGCAAAATGCAAAA
TATAGGAGGTAATAGAAGTG

Downstream 100 bases:

>100_bases
GAATTTTAAGAATTAAAAAAACAGGCCAAATTTGGTCTGTTTTTTTAATGACTATTGTTTTCGCTATTTTTTCGTGTTAT
AATTTTTAAAAAAGTAACAC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
METDVLVIGGSAGGILAALSAKKTYKDKKVTVVRMGERVMVPCGIPYIFGTLKDTSKNVIPDAMLTNAGIDLIIDEVLSI
DRENKKVNAKKSGEISYKKLILATGSLPIVPTFIPGHDLENVFTIKKDEEYLKFVQQKINEAQDVVVIGGGFIGVEMAEQ
VQLLGKNVTIIEVADKLLWQAFDHEYSDMAEATLKEHGITIKTNTKVTKLVGDTKVKEVELDTGEKIKADVVILAMGVKP
NTKLAEAAGIKLNEKGAITVDEYMRTNDPDIFAVGDCAEKKCFFTRKNVPILLASTAANEAKIAGVNVFQLRLVRENKGT
ISAFSTKIYNTAFAAAGLTETQAKAEGFDIVIGEFSTMDKHPGTLPNAKSVKIKLIFSRYSGVILGAQIAGGENVGEMIN
ILSLAIQKGTTASELNTFQVATHPLLTSSPVSYPINSAALDAMSKI

Sequences:

>Translated_446_residues
METDVLVIGGSAGGILAALSAKKTYKDKKVTVVRMGERVMVPCGIPYIFGTLKDTSKNVIPDAMLTNAGIDLIIDEVLSI
DRENKKVNAKKSGEISYKKLILATGSLPIVPTFIPGHDLENVFTIKKDEEYLKFVQQKINEAQDVVVIGGGFIGVEMAEQ
VQLLGKNVTIIEVADKLLWQAFDHEYSDMAEATLKEHGITIKTNTKVTKLVGDTKVKEVELDTGEKIKADVVILAMGVKP
NTKLAEAAGIKLNEKGAITVDEYMRTNDPDIFAVGDCAEKKCFFTRKNVPILLASTAANEAKIAGVNVFQLRLVRENKGT
ISAFSTKIYNTAFAAAGLTETQAKAEGFDIVIGEFSTMDKHPGTLPNAKSVKIKLIFSRYSGVILGAQIAGGENVGEMIN
ILSLAIQKGTTASELNTFQVATHPLLTSSPVSYPINSAALDAMSKI
>Mature_446_residues
METDVLVIGGSAGGILAALSAKKTYKDKKVTVVRMGERVMVPCGIPYIFGTLKDTSKNVIPDAMLTNAGIDLIIDEVLSI
DRENKKVNAKKSGEISYKKLILATGSLPIVPTFIPGHDLENVFTIKKDEEYLKFVQQKINEAQDVVVIGGGFIGVEMAEQ
VQLLGKNVTIIEVADKLLWQAFDHEYSDMAEATLKEHGITIKTNTKVTKLVGDTKVKEVELDTGEKIKADVVILAMGVKP
NTKLAEAAGIKLNEKGAITVDEYMRTNDPDIFAVGDCAEKKCFFTRKNVPILLASTAANEAKIAGVNVFQLRLVRENKGT
ISAFSTKIYNTAFAAAGLTETQAKAEGFDIVIGEFSTMDKHPGTLPNAKSVKIKLIFSRYSGVILGAQIAGGENVGEMIN
ILSLAIQKGTTASELNTFQVATHPLLTSSPVSYPINSAALDAMSKI

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=357, Percent_Identity=26.6106442577031, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI226437568, Length=357, Percent_Identity=26.6106442577031, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI21389617, Length=357, Percent_Identity=26.6106442577031, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI91199540, Length=348, Percent_Identity=28.735632183908, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI50301238, Length=360, Percent_Identity=26.1111111111111, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789065, Length=203, Percent_Identity=33.9901477832512, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786307, Length=341, Percent_Identity=28.1524926686217, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1789765, Length=352, Percent_Identity=23.5795454545455, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788892, Length=206, Percent_Identity=30.0970873786408, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082354, Length=356, Percent_Identity=25.8426966292135, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787352, Length=258, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789915, Length=366, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081717, Length=291, Percent_Identity=25.4295532646048, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=207, Percent_Identity=30.9178743961353, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32565766, Length=301, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983419, Length=136, Percent_Identity=36.0294117647059, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983429, Length=207, Percent_Identity=31.8840579710145, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324402, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325166, Length=343, Percent_Identity=23.9067055393586, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321091, Length=284, Percent_Identity=27.112676056338, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21358499, Length=348, Percent_Identity=28.448275862069, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281359715, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281359713, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639250, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18543267, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639252, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24639257, Length=232, Percent_Identity=27.1551724137931, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24585130, Length=344, Percent_Identity=21.5116279069767, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48027; Mature: 48027

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METDVLVIGGSAGGILAALSAKKTYKDKKVTVVRMGERVMVPCGIPYIFGTLKDTSKNVI
CCCCEEEEECCCCCEEEEEHHHHHCCCCEEEEEEECCEEEEECCCHHEEEECCCCCCCCC
PDAMLTNAGIDLIIDEVLSIDRENKKVNAKKSGEISYKKLILATGSLPIVPTFIPGHDLE
CCHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEEEEECCCCEEEEECCCCCCC
NVFTIKKDEEYLKFVQQKINEAQDVVVIGGGFIGVEMAEQVQLLGKNVTIIEVADKLLWQ
CEEEEECCHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHHHCCCEEEEHHHHHHHHH
AFDHEYSDMAEATLKEHGITIKTNTKVTKLVGDTKVKEVELDTGEKIKADVVILAMGVKP
HHCCCHHHHHHHHHHHCCEEEEECCEEEEEECCCEEEEEECCCCCCEEEEEEEEEECCCC
NTKLAEAAGIKLNEKGAITVDEYMRTNDPDIFAVGDCAEKKCFFTRKNVPILLASTAANE
CCCHHHHCCCEECCCCCEEHHHHHCCCCCCEEEECCCCCCCEEEEECCCCEEEEECCCCC
AKIAGVNVFQLRLVRENKGTISAFSTKIYNTAFAAAGLTETQAKAEGFDIVIGEFSTMDK
EEEECCEEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCC
HPGTLPNAKSVKIKLIFSRYSGVILGAQIAGGENVGEMINILSLAIQKGTTASELNTFQV
CCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCEEEE
ATHPLLTSSPVSYPINSAALDAMSKI
EECCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
METDVLVIGGSAGGILAALSAKKTYKDKKVTVVRMGERVMVPCGIPYIFGTLKDTSKNVI
CCCCEEEEECCCCCEEEEEHHHHHCCCCEEEEEEECCEEEEECCCHHEEEECCCCCCCCC
PDAMLTNAGIDLIIDEVLSIDRENKKVNAKKSGEISYKKLILATGSLPIVPTFIPGHDLE
CCHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEEEEECCCCEEEEECCCCCCC
NVFTIKKDEEYLKFVQQKINEAQDVVVIGGGFIGVEMAEQVQLLGKNVTIIEVADKLLWQ
CEEEEECCHHHHHHHHHHHCCCCCEEEECCCEEEHHHHHHHHHHCCCEEEEHHHHHHHHH
AFDHEYSDMAEATLKEHGITIKTNTKVTKLVGDTKVKEVELDTGEKIKADVVILAMGVKP
HHCCCHHHHHHHHHHHCCEEEEECCEEEEEECCCEEEEEECCCCCCEEEEEEEEEECCCC
NTKLAEAAGIKLNEKGAITVDEYMRTNDPDIFAVGDCAEKKCFFTRKNVPILLASTAANE
CCCHHHHCCCEECCCCCEEHHHHHCCCCCCEEEECCCCCCCEEEEECCCCEEEEECCCCC
AKIAGVNVFQLRLVRENKGTISAFSTKIYNTAFAAAGLTETQAKAEGFDIVIGEFSTMDK
EEEECCEEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCC
HPGTLPNAKSVKIKLIFSRYSGVILGAQIAGGENVGEMINILSLAIQKGTTASELNTFQV
CCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCEEEE
ATHPLLTSSPVSYPINSAALDAMSKI
EECCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]