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The map label for this gene is gntK [H]

Identifier: 167039733

GI number: 167039733

Start: 1119177

End: 1120697

Strand: Direct

Name: gntK [H]

Synonym: Teth514_1084

Alternate gene names: 167039733

Gene position: 1119177-1120697 (Clockwise)

Preceding gene: 167039732

Following gene: 167039735

Centisome position: 45.55

GC content: 34.71

Gene sequence:

>1521_bases
ATGGAATATTTAATAGGGGTAGATATAGGCACGACAGCTACTAAGGCTATAGCATTTAATAGGGAGGGTGTTATTATATC
TAAAAAGAGTGTTGAGTATCCTATATACCATCCAAAACCTACATGGAGTGAGCAGGACCCTGAAGAGATATTTCATGCGG
TTTTAATTTCTATAAAGGATGTAGTTGAAGAAAACAATGCAATGGGTAATAAACTTGAGGGTATAAGTTTTAGTGCAGCT
ATGCATAGTTTAATAGCTGTAGATCCTGAAGGGAAACCATTGACCAATTGTATAATCTGGGCTGATACAAGAAGTGAAGA
ATATGCAAAGAAAATGAAAGAAAGTAAGGTCGCACATTCCATATATCTAAAAACGGGAACTCCGATACACCCTATGTCAC
CACTTTGTAAACTTTTATGGATGAAGGAGAATAATAGTGAGATTTTTAATAAGGCGTATAAATTTATATCAATAAAGGAA
TATGTCTTTTACAAATTATTTTCAATATATATCGTTGATTATTCTATTGCATCTGCAACAGGGCTGTTTGATACTTATAA
ATTAAAATGGGATGATGAGGCACTGAATCTCATTGGCATTTCGCCTGATAGACTATCTATTCCTGTTTCTACAACACATA
CTGTTAGAGGGCTAAAAGATGGATATGCGAAGTTTTTAAATATACCTAAAAGTACACCATTTATAATTGGGGCTAGCGAT
GGATGTTTATCAAACCTAGGTACCAATGCTGTAAAACCTGGTGTAGCTGCTGTCACAATAGGTACCAGCGGTGCGATAAG
GGTAATTTCAAACAAACCGGTGTCAGATCCAGGCGAGAGAATATTTTCTTATATACTTACTGAAAATCATTATGTAGTAG
GCGGTCCAATCAATAACGGAGGTATAGTGCTAAGATGGTTTAGAGACAACTTTTATCCGTTAGAAGTTGAAAATGCAAAA
AAAGAAAATATTGATTTCTACGATATTTTAACTCAAAAAGTAGATAGTATTCCTGTGGGAGCAAGCGGATTAATATTTCT
CCCTTATTTACTAGGAGAGAGAGCACCCCATTGGGATGCCAATGCTCGAGGCGTTTTTTTTGGAGTAAATATAACCCATA
CGAGAGAACACTTTCTAAGGGCATTAATGGAGGGTGTAATATTTGGAATATATAGTGTAGGAAAAGTCTTAGAGCAGATT
ACTGGTAACATAGAAAAAATTTATGCTACTGGTGGGTTTGTAAGGTCATCACTATGGGTTAAGATCCTAGCGGATGTTTT
TAATAAAAAGGTTTTGGTAGCAGAAAGCTATGAGAGTTCATGTCTTGGTGCAGTTGTTCTAGGGATGAAGTCTCTCGGTT
TAATAAGCTCAATTGAAGATGTTGAAAAAATGGTTCCGATATCACAAACCATATATCCAGATAAAAATCACCATTATACT
TATACAAGGTTATTTGAAATATATGAACGTCTATATGATCAACTAAAAAATGAGTTTATTAGAATAATAAATCTGCAATA
A

Upstream 100 bases:

>100_bases
CCTAAGATGAAACGAGTTTCTGAATCTATAATAAACCAGATGTAATATTTTTCACCTGCGATTTTAAATACAGTTTCATC
CACAATTAGGAGGTAATTTT

Downstream 100 bases:

>100_bases
TATAATAAGAACTGAGTTATAAACTTGTTTTAATGCACTTTATATTATTTTGGGAAGATACTTATGATAAAGGTGATTGC
AATTGCATACAGATATTGGG

Product: carbohydrate kinase, FGGY

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MEYLIGVDIGTTATKAIAFNREGVIISKKSVEYPIYHPKPTWSEQDPEEIFHAVLISIKDVVEENNAMGNKLEGISFSAA
MHSLIAVDPEGKPLTNCIIWADTRSEEYAKKMKESKVAHSIYLKTGTPIHPMSPLCKLLWMKENNSEIFNKAYKFISIKE
YVFYKLFSIYIVDYSIASATGLFDTYKLKWDDEALNLIGISPDRLSIPVSTTHTVRGLKDGYAKFLNIPKSTPFIIGASD
GCLSNLGTNAVKPGVAAVTIGTSGAIRVISNKPVSDPGERIFSYILTENHYVVGGPINNGGIVLRWFRDNFYPLEVENAK
KENIDFYDILTQKVDSIPVGASGLIFLPYLLGERAPHWDANARGVFFGVNITHTREHFLRALMEGVIFGIYSVGKVLEQI
TGNIEKIYATGGFVRSSLWVKILADVFNKKVLVAESYESSCLGAVVLGMKSLGLISSIEDVEKMVPISQTIYPDKNHHYT
YTRLFEIYERLYDQLKNEFIRIINLQ

Sequences:

>Translated_506_residues
MEYLIGVDIGTTATKAIAFNREGVIISKKSVEYPIYHPKPTWSEQDPEEIFHAVLISIKDVVEENNAMGNKLEGISFSAA
MHSLIAVDPEGKPLTNCIIWADTRSEEYAKKMKESKVAHSIYLKTGTPIHPMSPLCKLLWMKENNSEIFNKAYKFISIKE
YVFYKLFSIYIVDYSIASATGLFDTYKLKWDDEALNLIGISPDRLSIPVSTTHTVRGLKDGYAKFLNIPKSTPFIIGASD
GCLSNLGTNAVKPGVAAVTIGTSGAIRVISNKPVSDPGERIFSYILTENHYVVGGPINNGGIVLRWFRDNFYPLEVENAK
KENIDFYDILTQKVDSIPVGASGLIFLPYLLGERAPHWDANARGVFFGVNITHTREHFLRALMEGVIFGIYSVGKVLEQI
TGNIEKIYATGGFVRSSLWVKILADVFNKKVLVAESYESSCLGAVVLGMKSLGLISSIEDVEKMVPISQTIYPDKNHHYT
YTRLFEIYERLYDQLKNEFIRIINLQ
>Mature_506_residues
MEYLIGVDIGTTATKAIAFNREGVIISKKSVEYPIYHPKPTWSEQDPEEIFHAVLISIKDVVEENNAMGNKLEGISFSAA
MHSLIAVDPEGKPLTNCIIWADTRSEEYAKKMKESKVAHSIYLKTGTPIHPMSPLCKLLWMKENNSEIFNKAYKFISIKE
YVFYKLFSIYIVDYSIASATGLFDTYKLKWDDEALNLIGISPDRLSIPVSTTHTVRGLKDGYAKFLNIPKSTPFIIGASD
GCLSNLGTNAVKPGVAAVTIGTSGAIRVISNKPVSDPGERIFSYILTENHYVVGGPINNGGIVLRWFRDNFYPLEVENAK
KENIDFYDILTQKVDSIPVGASGLIFLPYLLGERAPHWDANARGVFFGVNITHTREHFLRALMEGVIFGIYSVGKVLEQI
TGNIEKIYATGGFVRSSLWVKILADVFNKKVLVAESYESSCLGAVVLGMKSLGLISSIEDVEKMVPISQTIYPDKNHHYT
YTRLFEIYERLYDQLKNEFIRIINLQ

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=552, Percent_Identity=24.6376811594203, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI189409120, Length=458, Percent_Identity=25.1091703056769, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4504007, Length=458, Percent_Identity=25.1091703056769, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI42794763, Length=453, Percent_Identity=24.2825607064018, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI41393575, Length=459, Percent_Identity=24.8366013071895, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI88196792, Length=506, Percent_Identity=22.9249011857708, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI164663830, Length=576, Percent_Identity=23.7847222222222, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=26.1133603238866, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1790005, Length=516, Percent_Identity=24.4186046511628, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790361, Length=498, Percent_Identity=24.2971887550201, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787789, Length=513, Percent_Identity=26.1208576998051, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1789168, Length=512, Percent_Identity=23.046875, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789138, Length=499, Percent_Identity=21.4428857715431, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535599, Length=464, Percent_Identity=26.2931034482759, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321755, Length=510, Percent_Identity=25.4901960784314, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI17864214, Length=477, Percent_Identity=24.7379454926625, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24655555, Length=450, Percent_Identity=23.5555555555556, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655560, Length=450, Percent_Identity=23.5555555555556, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655570, Length=450, Percent_Identity=23.5555555555556, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655574, Length=450, Percent_Identity=23.5555555555556, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655565, Length=450, Percent_Identity=23.5555555555556, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24654573, Length=411, Percent_Identity=24.0875912408759, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656367, Length=527, Percent_Identity=18.595825426945, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24657106, Length=557, Percent_Identity=22.6211849192101, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24657102, Length=557, Percent_Identity=22.6211849192101, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357867, Length=540, Percent_Identity=18.8888888888889, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19922058, Length=506, Percent_Identity=20.3557312252964, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24656372, Length=344, Percent_Identity=20.3488372093023, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652871, Length=426, Percent_Identity=19.7183098591549, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56658; Mature: 56658

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLIGVDIGTTATKAIAFNREGVIISKKSVEYPIYHPKPTWSEQDPEEIFHAVLISIKD
CCEEEEECCCCCHHEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VVEENNAMGNKLEGISFSAAMHSLIAVDPEGKPLTNCIIWADTRSEEYAKKMKESKVAHS
HHHCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
IYLKTGTPIHPMSPLCKLLWMKENNSEIFNKAYKFISIKEYVFYKLFSIYIVDYSIASAT
EEEECCCCCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHC
GLFDTYKLKWDDEALNLIGISPDRLSIPVSTTHTVRGLKDGYAKFLNIPKSTPFIIGASD
CCCEEEEEEECCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCC
GCLSNLGTNAVKPGVAAVTIGTSGAIRVISNKPVSDPGERIFSYILTENHYVVGGPINNG
CHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEECEECCC
GIVLRWFRDNFYPLEVENAKKENIDFYDILTQKVDSIPVGASGLIFLPYLLGERAPHWDA
CEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCC
NARGVFFGVNITHTREHFLRALMEGVIFGIYSVGKVLEQITGNIEKIYATGGFVRSSLWV
CCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
KILADVFNKKVLVAESYESSCLGAVVLGMKSLGLISSIEDVEKMVPISQTIYPDKNHHYT
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCH
YTRLFEIYERLYDQLKNEFIRIINLQ
HHHHHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MEYLIGVDIGTTATKAIAFNREGVIISKKSVEYPIYHPKPTWSEQDPEEIFHAVLISIKD
CCEEEEECCCCCHHEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VVEENNAMGNKLEGISFSAAMHSLIAVDPEGKPLTNCIIWADTRSEEYAKKMKESKVAHS
HHHCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHEEE
IYLKTGTPIHPMSPLCKLLWMKENNSEIFNKAYKFISIKEYVFYKLFSIYIVDYSIASAT
EEEECCCCCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHC
GLFDTYKLKWDDEALNLIGISPDRLSIPVSTTHTVRGLKDGYAKFLNIPKSTPFIIGASD
CCCEEEEEEECCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCC
GCLSNLGTNAVKPGVAAVTIGTSGAIRVISNKPVSDPGERIFSYILTENHYVVGGPINNG
CHHHHCCCCCCCCCEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEECEECCC
GIVLRWFRDNFYPLEVENAKKENIDFYDILTQKVDSIPVGASGLIFLPYLLGERAPHWDA
CEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCC
NARGVFFGVNITHTREHFLRALMEGVIFGIYSVGKVLEQITGNIEKIYATGGFVRSSLWV
CCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
KILADVFNKKVLVAESYESSCLGAVVLGMKSLGLISSIEDVEKMVPISQTIYPDKNHHYT
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCH
YTRLFEIYERLYDQLKNEFIRIINLQ
HHHHHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]