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The map label for this gene is hgdC [H]

Identifier: 167039685

GI number: 167039685

Start: 1068764

End: 1069747

Strand: Direct

Name: hgdC [H]

Synonym: Teth514_1035

Alternate gene names: 167039685

Gene position: 1068764-1069747 (Clockwise)

Preceding gene: 167039683

Following gene: 167039686

Centisome position: 43.49

GC content: 39.13

Gene sequence:

>984_bases
ATGAAAGGTTACATGGGGATAGACGTAGGTTCTGTTAGTACTAATATTGCAGTAATTGATGAGAATAATAGAGTAATAGA
TTCTGTTTACATAAGGACACAGGGTCAACCTATTAAAGCAGTTCAAAATGCTCTTCGTGAGATAAAAAATAAAATAGGAG
ATATGGTTATTAAAGGAGTAGGCACCACAGGGAGTGCAAGGCAATTGACTGGCTTAATGGTGGGGGCAGACATTGTCAAA
AATGAAATTACTGCTCATGCCGTGGCAGCTTCCAATGTAATAAAGGATGTCAGAACGGTAATTGAAATAGGGGGACAAGA
CTCGAAGATCATAATTTTAAGAGATGGGGTAGTAGTAGATTTTGCAATGAATACAGTCTGTGCAGCAGGTACCGGTTCTT
TTCTTGACCAGCAAGCATACCGGTTAAATATTCCCATCGAACAGTTTGGAGACATAGCTTTGCAATCTAAAAGTCCTGTC
AGAATTGCGGGTAGATGTAGTGTTTTTGCAGAATCTGACATGATTCATAAGCAGCAGATGGGATATGCTCTTCCAGACAT
AATAAGTGGCTTGTGTGATGCACTTGTTAGAAATTATCTAAATAATGTAGGGAAGGGAAAAGAAATAAAAGAGCCAATAG
TGTTTCAAGGTGGTGTTGCTGCTAATAAAGGAATAAAGGCAGCCTTTGAAAAGGCATTAGGAATGAAAGTATATGTGCCT
GAACATTACGGTGTAATGGGAGCCATCGGGGCAGCAATATTGGCAAAAGAAGCAGTGAAAGAAAAAGGATATACTTCCTT
TAAAGGCTTTGAAGTAAGTGACTTTAAATATAGAGCGGTAGGTTTTGAGTGTACTGCTTGCCCAAATCGATGCGAAGTCG
TAGAATTCATACAAGGAGATGAGGTAATTTCAAGATGGGGAGATAAGTGTGGCAGGTGGTCTAACAGTACTAGTAAGAAA
GTCCATGCAAATACAGCTAGTTAA

Upstream 100 bases:

>100_bases
TTTTGCTTATTAATGCAATTTATTCGTTAATTGAAAGAGTATAAAAAATGATTTTGAAGGTAAAAATGTAAAATAAATGA
ACGATTTTAGGAGGTTAGAT

Downstream 100 bases:

>100_bases
TTAATGGGAGGCAATATAAGCCTCCCAATTTTAAACCTTATTTTTTTATATATGTCCATTTCCAATCATTATCCACGCCA
ACTGCATGCCTTACAATTCC

Product: putative CoA-substrate-specific enzyme activase

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MKGYMGIDVGSVSTNIAVIDENNRVIDSVYIRTQGQPIKAVQNALREIKNKIGDMVIKGVGTTGSARQLTGLMVGADIVK
NEITAHAVAASNVIKDVRTVIEIGGQDSKIIILRDGVVVDFAMNTVCAAGTGSFLDQQAYRLNIPIEQFGDIALQSKSPV
RIAGRCSVFAESDMIHKQQMGYALPDIISGLCDALVRNYLNNVGKGKEIKEPIVFQGGVAANKGIKAAFEKALGMKVYVP
EHYGVMGAIGAAILAKEAVKEKGYTSFKGFEVSDFKYRAVGFECTACPNRCEVVEFIQGDEVISRWGDKCGRWSNSTSKK
VHANTAS

Sequences:

>Translated_327_residues
MKGYMGIDVGSVSTNIAVIDENNRVIDSVYIRTQGQPIKAVQNALREIKNKIGDMVIKGVGTTGSARQLTGLMVGADIVK
NEITAHAVAASNVIKDVRTVIEIGGQDSKIIILRDGVVVDFAMNTVCAAGTGSFLDQQAYRLNIPIEQFGDIALQSKSPV
RIAGRCSVFAESDMIHKQQMGYALPDIISGLCDALVRNYLNNVGKGKEIKEPIVFQGGVAANKGIKAAFEKALGMKVYVP
EHYGVMGAIGAAILAKEAVKEKGYTSFKGFEVSDFKYRAVGFECTACPNRCEVVEFIQGDEVISRWGDKCGRWSNSTSKK
VHANTAS
>Mature_327_residues
MKGYMGIDVGSVSTNIAVIDENNRVIDSVYIRTQGQPIKAVQNALREIKNKIGDMVIKGVGTTGSARQLTGLMVGADIVK
NEITAHAVAASNVIKDVRTVIEIGGQDSKIIILRDGVVVDFAMNTVCAAGTGSFLDQQAYRLNIPIEQFGDIALQSKSPV
RIAGRCSVFAESDMIHKQQMGYALPDIISGLCDALVRNYLNNVGKGKEIKEPIVFQGGVAANKGIKAAFEKALGMKVYVP
EHYGVMGAIGAAILAKEAVKEKGYTSFKGFEVSDFKYRAVGFECTACPNRCEVVEFIQGDEVISRWGDKCGRWSNSTSKK
VHANTAS

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=258, Percent_Identity=32.9457364341085, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 35176; Mature: 35176

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGYMGIDVGSVSTNIAVIDENNRVIDSVYIRTQGQPIKAVQNALREIKNKIGDMVIKGV
CCCCEEEEECCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHEEEECC
GTTGSARQLTGLMVGADIVKNEITAHAVAASNVIKDVRTVIEIGGQDSKIIILRDGVVVD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEE
FAMNTVCAAGTGSFLDQQAYRLNIPIEQFGDIALQSKSPVRIAGRCSVFAESDMIHKQQM
EHHHHHHHCCCCHHHCCCCEEECCCHHHHCCEEECCCCCEEEEEEEEEEECHHHHHHHHC
GYALPDIISGLCDALVRNYLNNVGKGKEIKEPIVFQGGVAANKGIKAAFEKALGMKVYVP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEC
EHYGVMGAIGAAILAKEAVKEKGYTSFKGFEVSDFKYRAVGFECTACPNRCEVVEFIQGD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEECEEECCCCCHHHHHHHHCCH
EVISRWGDKCGRWSNSTSKKVHANTAS
HHHHHHHHHHCCCCCCCCCEEECCCCC
>Mature Secondary Structure
MKGYMGIDVGSVSTNIAVIDENNRVIDSVYIRTQGQPIKAVQNALREIKNKIGDMVIKGV
CCCCEEEEECCCCCEEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHEEEECC
GTTGSARQLTGLMVGADIVKNEITAHAVAASNVIKDVRTVIEIGGQDSKIIILRDGVVVD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEE
FAMNTVCAAGTGSFLDQQAYRLNIPIEQFGDIALQSKSPVRIAGRCSVFAESDMIHKQQM
EHHHHHHHCCCCHHHCCCCEEECCCHHHHCCEEECCCCCEEEEEEEEEEECHHHHHHHHC
GYALPDIISGLCDALVRNYLNNVGKGKEIKEPIVFQGGVAANKGIKAAFEKALGMKVYVP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEC
EHYGVMGAIGAAILAKEAVKEKGYTSFKGFEVSDFKYRAVGFECTACPNRCEVVEFIQGD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEECEEECCCCCHHHHHHHHCCH
EVISRWGDKCGRWSNSTSKKVHANTAS
HHHHHHHHHHCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]