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The map label for this gene is ahpF [H]

Identifier: 167039672

GI number: 167039672

Start: 1052952

End: 1054211

Strand: Direct

Name: ahpF [H]

Synonym: Teth514_1022

Alternate gene names: 167039672

Gene position: 1052952-1054211 (Clockwise)

Preceding gene: 167039671

Following gene: 167039673

Centisome position: 42.85

GC content: 37.22

Gene sequence:

>1260_bases
ATGCTTAACTATGATATAGTCATAATAGGTGGCGGCCCTGCAGGCTTGGGTGCTGCTGTAGAAGCCTATGAAAAGGGTGT
AAAAAATATAGTCATAATTGAAAGAGATAAATATCTTGGGGGTATTTTAGAGCAGTGCATACACAATGGATTTGGACTTC
AGGAATTTAAAGAAGAATTGACAGGACCAGAATATGCACAAAGATTCATTGATAAAGTAGAAGAATATGACATAAATGTA
ATGTTGGAAACTATGGTTTTGGAAATAACTCCTGATAGAATTGTAAAAGCTGTTAATTCTAAGGAAGGTGTGTTCACAAT
AAAAGCTGGAGCTATAATTTTAGCTATGGGATGCAGGGAAAGGCCGAGAGGTGCTATTATGATACCTGGCACTCGCCCAG
CAGGTATTCTCACAGCAGGTACTGCTCAGAGGTATGTAAATATGGAAGGATATCTTCCAGGGAAAGAAATAGTGATATTA
GGTTCTGGTGATGTTGGGCTTATTATGGCGAGAAGGCTTACATTAGAAGGAGCAAAAGTCAAAGCAGTTGTAGAACTCAT
GCCTTACTCTAGTGGACTTACAAGAAACATCGTTCAGTGTTTAGAGGACTTTAATATTCCTCTTCTTTTAAGTCACACTG
TCATTGAAATTCACGGCAAAGACAGGGTAGAAGGAGTTACAATTGCCAAAGTTGATGAAAATAGAGAGCCAATTATGGAG
ACTGCACAGTATATAAGTTGTGATACGTTAATACTTTCTGTTGGCTTGATTCCTGAAAATGAGCTCTCTCAAAAGGCCGG
TATAGAGCTAGACCCTATAACAGGAGGACCTATTGTAAATGAAATGTTAGAAACAAGTGTTCCTGGAATTTTTGCTTGTG
GCAATGTCCTTCAAGTTCACGACTTAGTTGACAATGTTACTGCAGAAGCGAGATTGGCAGCTAATTCAGCAATACGATTT
ATTCGAGAAGGTGAATTTGGAAAAAGCAATATTGCCGTAAAAGCTGGTAATGGCATACGTTATGTTGTTCCGCAAAAGAT
AAATGTAGATAACATAGAAAAAAGGATAAAATTCAGAATGAGACCTGTTAACGTTTATAACAATGCTATGTTAGCAGTAA
AGTCAGGAGACAAATATTTACTAAGACAAAAAAGGCAGCGCTTAACCCCTGGTGAAATGATTGATGTAAATTTAAGTAAA
GACATACTAAAAAATGCAAATCTTGAAGAAGGTATTGTCTTTTTAGTTGAGGAGGGATAA

Upstream 100 bases:

>100_bases
GTTACAAAGCATGGAAGAAATTCGAATATACTAACTGCAGAGACAAAAAAATTTTTATTAGAAAAAGCATCGGAGGTTTT
AAAGAAAGAGGTGTATGAGA

Downstream 100 bases:

>100_bases
AATGGAACTAAAAGAAATTACATGCATAGTTTGCCCCTTGGGCTGCAGGATACAAGTTGAAATGGAAGGAGGGGAGATAA
AAAGCGTAAAAGGATATTCT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MLNYDIVIIGGGPAGLGAAVEAYEKGVKNIVIIERDKYLGGILEQCIHNGFGLQEFKEELTGPEYAQRFIDKVEEYDINV
MLETMVLEITPDRIVKAVNSKEGVFTIKAGAIILAMGCRERPRGAIMIPGTRPAGILTAGTAQRYVNMEGYLPGKEIVIL
GSGDVGLIMARRLTLEGAKVKAVVELMPYSSGLTRNIVQCLEDFNIPLLLSHTVIEIHGKDRVEGVTIAKVDENREPIME
TAQYISCDTLILSVGLIPENELSQKAGIELDPITGGPIVNEMLETSVPGIFACGNVLQVHDLVDNVTAEARLAANSAIRF
IREGEFGKSNIAVKAGNGIRYVVPQKINVDNIEKRIKFRMRPVNVYNNAMLAVKSGDKYLLRQKRQRLTPGEMIDVNLSK
DILKNANLEEGIVFLVEEG

Sequences:

>Translated_419_residues
MLNYDIVIIGGGPAGLGAAVEAYEKGVKNIVIIERDKYLGGILEQCIHNGFGLQEFKEELTGPEYAQRFIDKVEEYDINV
MLETMVLEITPDRIVKAVNSKEGVFTIKAGAIILAMGCRERPRGAIMIPGTRPAGILTAGTAQRYVNMEGYLPGKEIVIL
GSGDVGLIMARRLTLEGAKVKAVVELMPYSSGLTRNIVQCLEDFNIPLLLSHTVIEIHGKDRVEGVTIAKVDENREPIME
TAQYISCDTLILSVGLIPENELSQKAGIELDPITGGPIVNEMLETSVPGIFACGNVLQVHDLVDNVTAEARLAANSAIRF
IREGEFGKSNIAVKAGNGIRYVVPQKINVDNIEKRIKFRMRPVNVYNNAMLAVKSGDKYLLRQKRQRLTPGEMIDVNLSK
DILKNANLEEGIVFLVEEG
>Mature_419_residues
MLNYDIVIIGGGPAGLGAAVEAYEKGVKNIVIIERDKYLGGILEQCIHNGFGLQEFKEELTGPEYAQRFIDKVEEYDINV
MLETMVLEITPDRIVKAVNSKEGVFTIKAGAIILAMGCRERPRGAIMIPGTRPAGILTAGTAQRYVNMEGYLPGKEIVIL
GSGDVGLIMARRLTLEGAKVKAVVELMPYSSGLTRNIVQCLEDFNIPLLLSHTVIEIHGKDRVEGVTIAKVDENREPIME
TAQYISCDTLILSVGLIPENELSQKAGIELDPITGGPIVNEMLETSVPGIFACGNVLQVHDLVDNVTAEARLAANSAIRF
IREGEFGKSNIAVKAGNGIRYVVPQKINVDNIEKRIKFRMRPVNVYNNAMLAVKSGDKYLLRQKRQRLTPGEMIDVNLSK
DILKNANLEEGIVFLVEEG

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=370, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI226437568, Length=370, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI65787454, Length=370, Percent_Identity=24.3243243243243, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32565766, Length=329, Percent_Identity=26.1398176291793, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012081
- InterPro:   IPR013027
- InterPro:   IPR002109
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 45917; Mature: 45917

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYDIVIIGGGPAGLGAAVEAYEKGVKNIVIIERDKYLGGILEQCIHNGFGLQEFKEEL
CCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHC
TGPEYAQRFIDKVEEYDINVMLETMVLEITPDRIVKAVNSKEGVFTIKAGAIILAMGCRE
CCHHHHHHHHHHHHHCCCEEEEEEEEEEECHHHHHHHHCCCCCEEEEECCEEEEEECCCC
RPRGAIMIPGTRPAGILTAGTAQRYVNMEGYLPGKEIVILGSGDVGLIMARRLTLEGAKV
CCCCEEEECCCCCCCEEEECCHHHEEECCCCCCCCEEEEEECCCEEEEEEEEEEECCCCE
KAVVELMPYSSGLTRNIVQCLEDFNIPLLLSHTVIEIHGKDRVEGVTIAKVDENREPIME
EEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHH
TAQYISCDTLILSVGLIPENELSQKAGIELDPITGGPIVNEMLETSVPGIFACGNVLQVH
HHHHHHHCEEEEEECCCCCHHHHHHCCCEECCCCCCHHHHHHHHHCCCCEEECCCHHHHH
DLVDNVTAEARLAANSAIRFIREGEFGKSNIAVKAGNGIRYVVPQKINVDNIEKRIKFRM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHEEEE
RPVNVYNNAMLAVKSGDKYLLRQKRQRLTPGEMIDVNLSKDILKNANLEEGIVFLVEEG
EEEEEECCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MLNYDIVIIGGGPAGLGAAVEAYEKGVKNIVIIERDKYLGGILEQCIHNGFGLQEFKEEL
CCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHC
TGPEYAQRFIDKVEEYDINVMLETMVLEITPDRIVKAVNSKEGVFTIKAGAIILAMGCRE
CCHHHHHHHHHHHHHCCCEEEEEEEEEEECHHHHHHHHCCCCCEEEEECCEEEEEECCCC
RPRGAIMIPGTRPAGILTAGTAQRYVNMEGYLPGKEIVILGSGDVGLIMARRLTLEGAKV
CCCCEEEECCCCCCCEEEECCHHHEEECCCCCCCCEEEEEECCCEEEEEEEEEEECCCCE
KAVVELMPYSSGLTRNIVQCLEDFNIPLLLSHTVIEIHGKDRVEGVTIAKVDENREPIME
EEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHH
TAQYISCDTLILSVGLIPENELSQKAGIELDPITGGPIVNEMLETSVPGIFACGNVLQVH
HHHHHHHCEEEEEECCCCCHHHHHHCCCEECCCCCCHHHHHHHHHCCCCEEECCCHHHHH
DLVDNVTAEARLAANSAIRFIREGEFGKSNIAVKAGNGIRYVVPQKINVDNIEKRIKFRM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHEEEE
RPVNVYNNAMLAVKSGDKYLLRQKRQRLTPGEMIDVNLSKDILKNANLEEGIVFLVEEG
EEEEEECCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1917890; 2760020 [H]