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The map label for this gene is regA [H]

Identifier: 167039637

GI number: 167039637

Start: 1015995

End: 1017014

Strand: Direct

Name: regA [H]

Synonym: Teth514_0985

Alternate gene names: 167039637

Gene position: 1015995-1017014 (Clockwise)

Preceding gene: 167039636

Following gene: 167039638

Centisome position: 41.35

GC content: 32.55

Gene sequence:

>1020_bases
ATGGCTACAATAAGGGATGTTGCAAAGTTGGCTGGGGTTTCTACAGCTACAGTTTCAAGAGTTTTAAATGAACAAGGAGG
TGTGAATAGCGAAACAAAACAAAAAGTTTTGGATGCAATTAAAAAGCTAAATTACAAACCGAACACTATAGCTAAAAATT
TTAGACAAAATAAGACTGACACGATTATTGTTGTGATTCCCGATATTACTAACACTTTTTTCTCAAAAATACTTTTGGGT
ATGCAAGATGTTGCAAATGCAAACGGATACAATGTGCTTTTATGCAATACCAATAATGATGTGGAGAAAGAACTTGAATA
TATAAGGTTTACAGAAAGAAGAGGAGCAGATGGAATTATCTTTTTAACAGCAAGAGTTAATTATACTAACATTTTGGAAT
TAACTAAAACTTGTCCAGTAGTTGTGGCTTGTGAATATATAGACAATTTAGACATTCCTACTGTTTCTATCAACAATTTT
AAAGCTGCTTATGAAGCTTCTGAATATTTAATAAAACTAGGGCATAAAAAGATTGCGTATATAAATGGTCCTGAAGGTAT
TGTATTATCCAGAGATAGATTAAGAGGATATAAGGCGGCTCTTGAAAGATATGGAATAGAAATTGATGAAAAACTTATTT
TTGAAGGAGACTTTTATTACGAAAGTGGTTATAAACATGCAAAGCAAATCTTAGAAAACGAAGCAACTGCTGTATTTACT
GCATCGGATGATATGGCTGCAGGCTTTATAAGATATTGCATAGATAATAATATTAAAGTACCGGAAGAGGTTTCAGTGGT
AGGATTTGATAATATTAAATTGGCTTCTATTATAAAGCCTGAATTAACTACTATAGCTCAGCCAATGTATGAAATTGGGA
CTACTGCAATGGATATGCTCATCAAATTGATTAAAGGGGAGGAGGTGGAAAAGAGAAACATAGTGTTAGAACACCAATTG
ATTGTGAGAGAAAGTTGTATGCCCTATGAAAAAAATTGTGTGAAAAGTAAAGGATACTGA

Upstream 100 bases:

>100_bases
TTATATTATACAAATAGTTACCGATTACATATACAATCGGTAAATCATATTAAAATAAGTCTTTGAATCATACGTAATAG
ATTACAAGGAGTGTGAGCAA

Downstream 100 bases:

>100_bases
GTAAAAAGTTTGGAGAAAATGCAACAAATATTTCGAATAATTAGAAAGGAGATTTGATATGAAGGTAGGTTATATGACCA
ATGCATGGGGGAGTGTAGTA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MATIRDVAKLAGVSTATVSRVLNEQGGVNSETKQKVLDAIKKLNYKPNTIAKNFRQNKTDTIIVVIPDITNTFFSKILLG
MQDVANANGYNVLLCNTNNDVEKELEYIRFTERRGADGIIFLTARVNYTNILELTKTCPVVVACEYIDNLDIPTVSINNF
KAAYEASEYLIKLGHKKIAYINGPEGIVLSRDRLRGYKAALERYGIEIDEKLIFEGDFYYESGYKHAKQILENEATAVFT
ASDDMAAGFIRYCIDNNIKVPEEVSVVGFDNIKLASIIKPELTTIAQPMYEIGTTAMDMLIKLIKGEEVEKRNIVLEHQL
IVRESCMPYEKNCVKSKGY

Sequences:

>Translated_339_residues
MATIRDVAKLAGVSTATVSRVLNEQGGVNSETKQKVLDAIKKLNYKPNTIAKNFRQNKTDTIIVVIPDITNTFFSKILLG
MQDVANANGYNVLLCNTNNDVEKELEYIRFTERRGADGIIFLTARVNYTNILELTKTCPVVVACEYIDNLDIPTVSINNF
KAAYEASEYLIKLGHKKIAYINGPEGIVLSRDRLRGYKAALERYGIEIDEKLIFEGDFYYESGYKHAKQILENEATAVFT
ASDDMAAGFIRYCIDNNIKVPEEVSVVGFDNIKLASIIKPELTTIAQPMYEIGTTAMDMLIKLIKGEEVEKRNIVLEHQL
IVRESCMPYEKNCVKSKGY
>Mature_338_residues
ATIRDVAKLAGVSTATVSRVLNEQGGVNSETKQKVLDAIKKLNYKPNTIAKNFRQNKTDTIIVVIPDITNTFFSKILLGM
QDVANANGYNVLLCNTNNDVEKELEYIRFTERRGADGIIFLTARVNYTNILELTKTCPVVVACEYIDNLDIPTVSINNFK
AAYEASEYLIKLGHKKIAYINGPEGIVLSRDRLRGYKAALERYGIEIDEKLIFEGDFYYESGYKHAKQILENEATAVFTA
SDDMAAGFIRYCIDNNIKVPEEVSVVGFDNIKLASIIKPELTTIAQPMYEIGTTAMDMLIKLIKGEEVEKRNIVLEHQLI
VRESCMPYEKNCVKSKGY

Specific function: Involved in the regulation of amylase production [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=327, Percent_Identity=40.0611620795107, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=35.1515151515151, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=35.1515151515151, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1789068, Length=336, Percent_Identity=31.547619047619, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787580, Length=325, Percent_Identity=31.0769230769231, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=30.976430976431, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1788474, Length=313, Percent_Identity=30.9904153354633, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=31.9526627218935, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=27.7258566978193, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1787906, Length=335, Percent_Identity=25.9701492537313, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790715, Length=334, Percent_Identity=26.9461077844311, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786268, Length=303, Percent_Identity=22.7722772277228, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=23.6024844720497, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789456, Length=325, Percent_Identity=26.4615384615385, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38099; Mature: 37968

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIRDVAKLAGVSTATVSRVLNEQGGVNSETKQKVLDAIKKLNYKPNTIAKNFRQNKTD
CCCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
TIIVVIPDITNTFFSKILLGMQDVANANGYNVLLCNTNNDVEKELEYIRFTERRGADGII
EEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
FLTARVNYTNILELTKTCPVVVACEYIDNLDIPTVSINNFKAAYEASEYLIKLGHKKIAY
EEEEECCHHHHHHHHHCCCEEEEEEHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
INGPEGIVLSRDRLRGYKAALERYGIEIDEKLIFEGDFYYESGYKHAKQILENEATAVFT
EECCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCEEECCCHHHHHHHHCCCCCEEEE
ASDDMAAGFIRYCIDNNIKVPEEVSVVGFDNIKLASIIKPELTTIAQPMYEIGTTAMDML
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
IKLIKGEEVEKRNIVLEHQLIVRESCMPYEKNCVKSKGY
HHHHCCCCCHHHCEEEHHHHHHHHCCCCHHHHHHCCCCC
>Mature Secondary Structure 
ATIRDVAKLAGVSTATVSRVLNEQGGVNSETKQKVLDAIKKLNYKPNTIAKNFRQNKTD
CCHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
TIIVVIPDITNTFFSKILLGMQDVANANGYNVLLCNTNNDVEKELEYIRFTERRGADGII
EEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEE
FLTARVNYTNILELTKTCPVVVACEYIDNLDIPTVSINNFKAAYEASEYLIKLGHKKIAY
EEEEECCHHHHHHHHHCCCEEEEEEHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
INGPEGIVLSRDRLRGYKAALERYGIEIDEKLIFEGDFYYESGYKHAKQILENEATAVFT
EECCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCEEECCCHHHHHHHHCCCCCEEEE
ASDDMAAGFIRYCIDNNIKVPEEVSVVGFDNIKLASIIKPELTTIAQPMYEIGTTAMDML
CCCCHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEHHCCHHHHHHHHHHHHHHHHHHHHH
IKLIKGEEVEKRNIVLEHQLIVRESCMPYEKNCVKSKGY
HHHHCCCCCHHHCEEEHHHHHHHHCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7539689 [H]