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The map label for this gene is mrpE [H]

Identifier: 167039563

GI number: 167039563

Start: 936941

End: 937441

Strand: Direct

Name: mrpE [H]

Synonym: Teth514_0911

Alternate gene names: 167039563

Gene position: 936941-937441 (Clockwise)

Preceding gene: 167039562

Following gene: 167039564

Centisome position: 38.13

GC content: 29.74

Gene sequence:

>501_bases
ATGACGAATCTCATATATTTTTATACTGTTCTTTTCATTTTTTGGTTTGCTTCGTCTGGAAAAACAGATTTCATAAATCT
ATCTTTAGGGTTTTTGGCAAGTATTTTTGCAATGGAAGTTTATAAAAAATTCTTTTATATTTCAAAGATGAAGGAAATAA
ATCTTATAAAATTTCTTCTCTCATTCTTTAATTATATAGTAAACTTGATAAAAAATATTTTAATGGCAGGAATTCAGGTA
ACGAGGATTGTCCTGTCGAGAGAAATGAAGATTTCACCGAGGATTATAAAAGTTCGGAAAAAATTTAAGACCAATTTTGG
AAGGGTTATAGCTGCTACAACAATAACGTTGACTCCGGGCACATTGACAATAGATTTTTATAACGATACTTTTATAATAC
ATGCTTTAAATTCCCAAAATGCTGAAGAAATGCTGGAATGGCCCCTGGAAAAAGTTATTTTGGAGTTGGAGGATGTTTTT
TATGGAAATGGAAATACTTAA

Upstream 100 bases:

>100_bases
AAAAACCTAAAAATACTTGATACGTTCTTTTATTTATGATACCATTTTTATTGGTATAATATTCTTAAGCTATAAAATTT
ATATTTGAGGTAATGATAAT

Downstream 100 bases:

>100_bases
GACTCTAGGGGGCATAATCCTATGTATTACAATAATAATATCTATTTTGGCCAGCATAAATAGAAAGGGAGTTCTTGAAA
AAGTCGTAATAACAAATATA

Product: cation antiporter

Products: NA

Alternate protein names: Mrp complex subunit E; Multiple resistance and pH homeostasis protein E [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTNLIYFYTVLFIFWFASSGKTDFINLSLGFLASIFAMEVYKKFFYISKMKEINLIKFLLSFFNYIVNLIKNILMAGIQV
TRIVLSREMKISPRIIKVRKKFKTNFGRVIAATTITLTPGTLTIDFYNDTFIIHALNSQNAEEMLEWPLEKVILELEDVF
YGNGNT

Sequences:

>Translated_166_residues
MTNLIYFYTVLFIFWFASSGKTDFINLSLGFLASIFAMEVYKKFFYISKMKEINLIKFLLSFFNYIVNLIKNILMAGIQV
TRIVLSREMKISPRIIKVRKKFKTNFGRVIAATTITLTPGTLTIDFYNDTFIIHALNSQNAEEMLEWPLEKVILELEDVF
YGNGNT
>Mature_165_residues
TNLIYFYTVLFIFWFASSGKTDFINLSLGFLASIFAMEVYKKFFYISKMKEINLIKFLLSFFNYIVNLIKNILMAGIQVT
RIVLSREMKISPRIIKVRKKFKTNFGRVIAATTITLTPGTLTIDFYNDTFIIHALNSQNAEEMLEWPLEKVILELEDVFY
GNGNT

Specific function: Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance [H]

COG id: COG1863

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhE subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002758 [H]

Pfam domain/function: PF01899 MNHE [H]

EC number: NA

Molecular weight: Translated: 19317; Mature: 19186

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLIYFYTVLFIFWFASSGKTDFINLSLGFLASIFAMEVYKKFFYISKMKEINLIKFLL
CCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFFNYIVNLIKNILMAGIQVTRIVLSREMKISPRIIKVRKKFKTNFGRVIAATTITLTPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCC
TLTIDFYNDTFIIHALNSQNAEEMLEWPLEKVILELEDVFYGNGNT
EEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TNLIYFYTVLFIFWFASSGKTDFINLSLGFLASIFAMEVYKKFFYISKMKEINLIKFLL
CCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFFNYIVNLIKNILMAGIQVTRIVLSREMKISPRIIKVRKKFKTNFGRVIAATTITLTPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCC
TLTIDFYNDTFIIHALNSQNAEEMLEWPLEKVILELEDVFYGNGNT
EEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]