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The map label for this gene is radA [H]

Identifier: 167039490

GI number: 167039490

Start: 873191

End: 874564

Strand: Direct

Name: radA [H]

Synonym: Teth514_0836

Alternate gene names: 167039490

Gene position: 873191-874564 (Clockwise)

Preceding gene: 167039489

Following gene: 167039492

Centisome position: 35.54

GC content: 36.46

Gene sequence:

>1374_bases
ATGGCCAAATCAACTACAAAGTTTGTGTGTAGAGAGTGTGGCTTTGAAAGTAGTAAATGGATGGGAAGATGTCCTAATTG
TGACAGCTGGAATTCTTTTGAGGAAGAAGCTATAGAGAGTTCAAAAAATTTTAGGAAAACTAAAGATAGATCACAAATAT
ACCTTCTTGAAGATGTAACTTTTTCAGAAGAGGAAAGAATAAGGACAGGGATTGAAGAGTTTGACAGGGTTTTAGGCGGC
GGAATTGTAAAAGGTTCTCTTGTTTTAATAGGTGGTGACCCAGGAATTGGGAAGTCTACTTTGCTATTACAAGTAGCAGG
TAATATTTCTGATAGCAGGAAGGTACTTTATGTGTCAGGAGAGGAATCAGTTCAACAGATTAAATTGAGGGCAGATAGAA
TTTTGAAAGAGAAACAGCGAATATATCTTTTGTGCGAAACAAATATAGAAGAGATAGAGAGAAAAATTGATGAGAATAAG
CCGGATTTTGTTATTATTGATTCTATACAGACGATATACACTGAGGAAAGTGAGACAATACCGGGAAGTGTGTCTCAGAT
AAGACAAGTGACTCAAAAGCTGATGGAAATTGCAAAACAAAAAGACATAAGTATTTTTTTGATAGGGCATGTTACAAAAG
AAGGAGCAATAGCGGGACCCAAAGTTTTGGAACATATGGTGGACACGGTTTTATATTTTGAAGGGGATAGGACCCAGTCT
TTTAGGATATTGCGGGCTGTAAAAAACCGTTTTGGCGCAACTCACGAAATAGGAGTTTTTGATATGGAGGAGGATGGGCT
TTGTGAGATAAGCAATCCTTCTGAATTTATTCTCTCAAATAAGCCGAAAGATGTTTCAGGGACTGCTGTTGTATCTTCTA
TTCAAGGGACGAGGCCAATTTTAATGGAAGTTCAGTCTTTGATATGTAAGACTACTTTTGGAGTGCCGCGAAGAATGGCC
ACTGGATTTGACTACAATCGCTTTATATTGCTTTTGGCAGTTATAGAAAAAAGACTGGGCATAAATCTTTCACAATTTGA
TGCATATGTAAATGTGGCTGGAGGAATGAAAATTCAAGAGCCAGCTGCTGACCTTGGAATAATTGCTTCATCTCTTTCTG
GATATTTTAATATACCTATTCCTGAAGATGTTTGTTTTATAGGAGAGGTGGGATTGACGGGAGAAGTAAGAGGAGTCAGC
AATATAGATAAACGAATAGGTGAAGCACAAAAGATGGGATTTTCTCAAGTTTTTATTCCTGAGATGAAAACAAAAGAAAT
AAAAAAGTTTGGGAATATAAAGGTTACTAAAATAAAGGACATAAAGGATATTATGGATTTTTTGAGAGAAAGAGAACAAA
AAGCGTCTTCATAA

Upstream 100 bases:

>100_bases
CGCTATAAAAAAGGCTTAGCCTCGGGCTAAGTCTTTTTTATAGGAGAGGTTTAAAAGTGTGATATAATTAAAAGAGAATT
TTGTGAAAGATGGTGGAGGT

Downstream 100 bases:

>100_bases
GGAAGACGCTTCAGACTGTAGACAAACTTTCGTAAAGGAGATATTTTGCATAAGGAGCGACTTGTTACAAAGCGCTAACA
AAACTTAGCAAGACCGAGGG

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MAKSTTKFVCRECGFESSKWMGRCPNCDSWNSFEEEAIESSKNFRKTKDRSQIYLLEDVTFSEEERIRTGIEEFDRVLGG
GIVKGSLVLIGGDPGIGKSTLLLQVAGNISDSRKVLYVSGEESVQQIKLRADRILKEKQRIYLLCETNIEEIERKIDENK
PDFVIIDSIQTIYTEESETIPGSVSQIRQVTQKLMEIAKQKDISIFLIGHVTKEGAIAGPKVLEHMVDTVLYFEGDRTQS
FRILRAVKNRFGATHEIGVFDMEEDGLCEISNPSEFILSNKPKDVSGTAVVSSIQGTRPILMEVQSLICKTTFGVPRRMA
TGFDYNRFILLLAVIEKRLGINLSQFDAYVNVAGGMKIQEPAADLGIIASSLSGYFNIPIPEDVCFIGEVGLTGEVRGVS
NIDKRIGEAQKMGFSQVFIPEMKTKEIKKFGNIKVTKIKDIKDIMDFLREREQKASS

Sequences:

>Translated_457_residues
MAKSTTKFVCRECGFESSKWMGRCPNCDSWNSFEEEAIESSKNFRKTKDRSQIYLLEDVTFSEEERIRTGIEEFDRVLGG
GIVKGSLVLIGGDPGIGKSTLLLQVAGNISDSRKVLYVSGEESVQQIKLRADRILKEKQRIYLLCETNIEEIERKIDENK
PDFVIIDSIQTIYTEESETIPGSVSQIRQVTQKLMEIAKQKDISIFLIGHVTKEGAIAGPKVLEHMVDTVLYFEGDRTQS
FRILRAVKNRFGATHEIGVFDMEEDGLCEISNPSEFILSNKPKDVSGTAVVSSIQGTRPILMEVQSLICKTTFGVPRRMA
TGFDYNRFILLLAVIEKRLGINLSQFDAYVNVAGGMKIQEPAADLGIIASSLSGYFNIPIPEDVCFIGEVGLTGEVRGVS
NIDKRIGEAQKMGFSQVFIPEMKTKEIKKFGNIKVTKIKDIKDIMDFLREREQKASS
>Mature_456_residues
AKSTTKFVCRECGFESSKWMGRCPNCDSWNSFEEEAIESSKNFRKTKDRSQIYLLEDVTFSEEERIRTGIEEFDRVLGGG
IVKGSLVLIGGDPGIGKSTLLLQVAGNISDSRKVLYVSGEESVQQIKLRADRILKEKQRIYLLCETNIEEIERKIDENKP
DFVIIDSIQTIYTEESETIPGSVSQIRQVTQKLMEIAKQKDISIFLIGHVTKEGAIAGPKVLEHMVDTVLYFEGDRTQSF
RILRAVKNRFGATHEIGVFDMEEDGLCEISNPSEFILSNKPKDVSGTAVVSSIQGTRPILMEVQSLICKTTFGVPRRMAT
GFDYNRFILLLAVIEKRLGINLSQFDAYVNVAGGMKIQEPAADLGIIASSLSGYFNIPIPEDVCFIGEVGLTGEVRGVSN
IDKRIGEAQKMGFSQVFIPEMKTKEIKKFGNIKVTKIKDIKDIMDFLREREQKASS

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=463, Percent_Identity=40.8207343412527, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 51178; Mature: 51046

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSTTKFVCRECGFESSKWMGRCPNCDSWNSFEEEAIESSKNFRKTKDRSQIYLLEDVT
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
FSEEERIRTGIEEFDRVLGGGIVKGSLVLIGGDPGIGKSTLLLQVAGNISDSRKVLYVSG
CCHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECC
EESVQQIKLRADRILKEKQRIYLLCETNIEEIERKIDENKPDFVIIDSIQTIYTEESETI
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEEEECHHHHHCCCCCCC
PGSVSQIRQVTQKLMEIAKQKDISIFLIGHVTKEGAIAGPKVLEHMVDTVLYFEGDRTQS
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHEEECCCCCHH
FRILRAVKNRFGATHEIGVFDMEEDGLCEISNPSEFILSNKPKDVSGTAVVSSIQGTRPI
HHHHHHHHHHCCCCEECEEEECCCCCCEEECCCHHHHCCCCCCCCCCHHHHHHCCCCCHH
LMEVQSLICKTTFGVPRRMATGFDYNRFILLLAVIEKRLGINLSQFDAYVNVAGGMKIQE
HHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHEEECCCCEECC
PAADLGIIASSLSGYFNIPIPEDVCFIGEVGLTGEVRGVSNIDKRIGEAQKMGFSQVFIP
CHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEECC
EMKTKEIKKFGNIKVTKIKDIKDIMDFLREREQKASS
CCHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKSTTKFVCRECGFESSKWMGRCPNCDSWNSFEEEAIESSKNFRKTKDRSQIYLLEDVT
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
FSEEERIRTGIEEFDRVLGGGIVKGSLVLIGGDPGIGKSTLLLQVAGNISDSRKVLYVSG
CCHHHHHHHHHHHHHHHHCCCEEECEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECC
EESVQQIKLRADRILKEKQRIYLLCETNIEEIERKIDENKPDFVIIDSIQTIYTEESETI
HHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCEEEEECHHHHHCCCCCCC
PGSVSQIRQVTQKLMEIAKQKDISIFLIGHVTKEGAIAGPKVLEHMVDTVLYFEGDRTQS
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHEEECCCCCHH
FRILRAVKNRFGATHEIGVFDMEEDGLCEISNPSEFILSNKPKDVSGTAVVSSIQGTRPI
HHHHHHHHHHCCCCEECEEEECCCCCCEEECCCHHHHCCCCCCCCCCHHHHHHCCCCCHH
LMEVQSLICKTTFGVPRRMATGFDYNRFILLLAVIEKRLGINLSQFDAYVNVAGGMKIQE
HHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHEEECCCCEECC
PAADLGIIASSLSGYFNIPIPEDVCFIGEVGLTGEVRGVSNIDKRIGEAQKMGFSQVFIP
CHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEECC
EMKTKEIKKFGNIKVTKIKDIKDIMDFLREREQKASS
CCHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]