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The map label for this gene is clpB [H]

Identifier: 167039489

GI number: 167039489

Start: 870659

End: 873109

Strand: Direct

Name: clpB [H]

Synonym: Teth514_0835

Alternate gene names: 167039489

Gene position: 870659-873109 (Clockwise)

Preceding gene: 167039488

Following gene: 167039490

Centisome position: 35.43

GC content: 36.8

Gene sequence:

>2451_bases
ATGGCGATGTTTGGAAGATTTACAGAAAGAGCTCAAAAAGCTCTTTATTTGGCTCAAGAGGAAGCGAGGTCTTTTTATCA
TAACTATGTAGGGACAGAACACATTTTATTAGGATTGTTAAAAGAAGATGAAGGAATTGCAGCAAGAGTTTTAAAAAAAC
TGGGAGTAACTTATGAAACTACAAGAGAGAAGGTATTGTCTTTGATTGGAATGGGAAATATTCCAGGAGACGTGGTAGGT
TATACACCACGAGCTAAAAGGGTATTGGAATTGAGTCTTAGTGAGGCAAGGAGATTTAATACCAGCTATGTAGGGACAGA
GCATATTTTGTTAGGACTTTTAAGAGAAGGCGAAGGAGTTGCTGTAAGAATTTTAATGGAACAAGGTATAGATTTCAATA
GGGTGAGAGAGGAGATTGTAAAAATGCTTAATGAAGAGCCTGCAGGAGGACCTGCAAAGGCTGCAAAAGTTAAAAATACC
AATACACCTACTTTAAATCAATTTGGAAGAGATTTAACTGAGCTTGCAAGAGACGGCAAACTTGACCCTGTAATAGGAAG
AGAAAAAGAGATTGAAAGAGTTATACAAATCTTAAGCAGAAGGACAAAGAATAACCCTGTCCTAATAGGTGAACCGGGTG
TCGGTAAAACTGCTATTGTAGAAGGTCTTGCGCAAAAGATTGTAGAAGGAGAAATTCCTGAAATTTTGAAAGATAAAAGA
GTTGTAACTTTAGACATGGCTTCTATGGTAGCAGGTACAAAGTACAGAGGCGAATTTGAAGATAGGTTAAAAACAGTATT
AAATGAGGTTATAAAGGCAGGAAATGTGATACTATTTATAGATGAGATGCACACTTTGATAGGAGCAGGTGCAGCAGAGG
GTGCAATAGATGCATCAAATATTCTAAAACCGGCACTTGCAAGAGGTGAAATTCAAGTAGTTGGAGCTACTACTTTGGAT
GAGTACAGAAAATATGTAGAAAGAGACCCTGCATTAGAGAGACGATTCCAACCAATAATTGTAGATGAACCAACTGTGGA
GGAGACTATTGAGATATTAAAGGGCTTGAGAGATAAGTATGAAGCCCATCATAGGGTTAAAATTACTGACGAAGCTTTAG
AAGCAGCAGCTAGACTTTCTCACAGATATATTGCAGATAGATTTTTACCTGATAAAGCTATAGACTTAATAGATGAAGCA
GCTTCTCGCGTAAGACTAAAGACAGTGACAGCTCCTCCAGAGATAAAAGAACTGGAAGATAAAATCAATGACCTTATAAA
AGAGAAGGAAGAAGCGATAAGAACTCAAGAATACGAAAAAGCTGCAAAAATAAGAGATGAAGAACAAAAATTGAGAGAAG
AATTAGAAAAATTAAAAGCTAAATGGCAACAAAATTCTCTTTCTAATGAAAAAAGTGTAGGACCTGAAGAAATCGCACAA
GTCGTATCTCTGTGGACAGGAATACCTGTTAAAAAGTTAGCTGAAGAGGAATCAGAGAGATTGCTCCACTTAGAGGAGGT
ATTGCATGAAAGAGTTATAGGACAAGATGAAGCAGTAGAAGCAGTGGCAAGAGCTATAAGAAGGGCAAGAGTAGGCTTAA
AAGATCCAAAAAGGCCAATAGGTTCATTTATCTTCTTGGGGCCTACTGGTGTTGGTAAAACAGAACTTACAAAGGCTTTG
GCAGAAGCTCTTTTTGGTGACGAAAATGCTATGATTAGGCTTGATATGTCAGAATACATGGAAAGACACACCGTTTCTAA
ACTTATTGGTTCACCTCCAGGATATGTAGGATTTGAAGAAGGAGGACAATTAACAGAAAAAGTAAGAAGAAAACCCTATT
CAGTAATCTTGCTGGATGAAATTGAAAAAGCGCATCCTGACGTGTTTAACATTCTCCTTCAAATATTAGAAGATGGACGA
CTCACAGATTCAAAAGGTAGAACTGTAGACTTTAAAAATACCGTTATAATCATGACATCAAACGTGGGAGCAGAACTTTT
GAAAAAGCAATCTACTTTAGGATTTATGCCTCAAGAAAAAGAAGACAAAGCCTCTTATGACAAAATAAAAGAAACATTGA
TGGCAGAGTTGAGAAAGACCTTTAGACCTGAATTCTTAAATAGGGTGGATGAGATAATTGTATTTCATCAACTCTCAAAA
GAAGATATTGAAAAGATTGCTGATATAATGATTAAAGAATTGAATGACAGACTAAAAGAGAACGACATTAAACTGGACTT
TACTCCTGAAGCCAAAGAGGAAATTATCAAACAGGGATATGACCCCAACTACGGTGCAAGGCCTTTAAGAAGAGTTATAC
AAAGAATTGTAGAGAATCAACTGTCTGAACTTATGTTGCAAGGAGAAGTGAAGCCAGGAGATGAACTTATTGTAACTGCA
AAAGACGGAAAAATAGAGTTTGTGAAAAAGGACGCTATAAAAAAGGCTTAG

Upstream 100 bases:

>100_bases
TTATGGCATTCAATTAGACCCCTATGAGAGAGATGTTAAAAGGGCAGAATATGTAGTAAGTCAAATAAACAAAAAAGATA
ATTTATAGGAGGTGTTTGTT

Downstream 100 bases:

>100_bases
CCTCGGGCTAAGTCTTTTTTATAGGAGAGGTTTAAAAGTGTGATATAATTAAAAGAGAATTTTGTGAAAGATGGTGGAGG
TATGGCCAAATCAACTACAA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 816; Mature: 815

Protein sequence:

>816_residues
MAMFGRFTERAQKALYLAQEEARSFYHNYVGTEHILLGLLKEDEGIAARVLKKLGVTYETTREKVLSLIGMGNIPGDVVG
YTPRAKRVLELSLSEARRFNTSYVGTEHILLGLLREGEGVAVRILMEQGIDFNRVREEIVKMLNEEPAGGPAKAAKVKNT
NTPTLNQFGRDLTELARDGKLDPVIGREKEIERVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVEGEIPEILKDKR
VVTLDMASMVAGTKYRGEFEDRLKTVLNEVIKAGNVILFIDEMHTLIGAGAAEGAIDASNILKPALARGEIQVVGATTLD
EYRKYVERDPALERRFQPIIVDEPTVEETIEILKGLRDKYEAHHRVKITDEALEAAARLSHRYIADRFLPDKAIDLIDEA
ASRVRLKTVTAPPEIKELEDKINDLIKEKEEAIRTQEYEKAAKIRDEEQKLREELEKLKAKWQQNSLSNEKSVGPEEIAQ
VVSLWTGIPVKKLAEEESERLLHLEEVLHERVIGQDEAVEAVARAIRRARVGLKDPKRPIGSFIFLGPTGVGKTELTKAL
AEALFGDENAMIRLDMSEYMERHTVSKLIGSPPGYVGFEEGGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQILEDGR
LTDSKGRTVDFKNTVIIMTSNVGAELLKKQSTLGFMPQEKEDKASYDKIKETLMAELRKTFRPEFLNRVDEIIVFHQLSK
EDIEKIADIMIKELNDRLKENDIKLDFTPEAKEEIIKQGYDPNYGARPLRRVIQRIVENQLSELMLQGEVKPGDELIVTA
KDGKIEFVKKDAIKKA

Sequences:

>Translated_816_residues
MAMFGRFTERAQKALYLAQEEARSFYHNYVGTEHILLGLLKEDEGIAARVLKKLGVTYETTREKVLSLIGMGNIPGDVVG
YTPRAKRVLELSLSEARRFNTSYVGTEHILLGLLREGEGVAVRILMEQGIDFNRVREEIVKMLNEEPAGGPAKAAKVKNT
NTPTLNQFGRDLTELARDGKLDPVIGREKEIERVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVEGEIPEILKDKR
VVTLDMASMVAGTKYRGEFEDRLKTVLNEVIKAGNVILFIDEMHTLIGAGAAEGAIDASNILKPALARGEIQVVGATTLD
EYRKYVERDPALERRFQPIIVDEPTVEETIEILKGLRDKYEAHHRVKITDEALEAAARLSHRYIADRFLPDKAIDLIDEA
ASRVRLKTVTAPPEIKELEDKINDLIKEKEEAIRTQEYEKAAKIRDEEQKLREELEKLKAKWQQNSLSNEKSVGPEEIAQ
VVSLWTGIPVKKLAEEESERLLHLEEVLHERVIGQDEAVEAVARAIRRARVGLKDPKRPIGSFIFLGPTGVGKTELTKAL
AEALFGDENAMIRLDMSEYMERHTVSKLIGSPPGYVGFEEGGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQILEDGR
LTDSKGRTVDFKNTVIIMTSNVGAELLKKQSTLGFMPQEKEDKASYDKIKETLMAELRKTFRPEFLNRVDEIIVFHQLSK
EDIEKIADIMIKELNDRLKENDIKLDFTPEAKEEIIKQGYDPNYGARPLRRVIQRIVENQLSELMLQGEVKPGDELIVTA
KDGKIEFVKKDAIKKA
>Mature_815_residues
AMFGRFTERAQKALYLAQEEARSFYHNYVGTEHILLGLLKEDEGIAARVLKKLGVTYETTREKVLSLIGMGNIPGDVVGY
TPRAKRVLELSLSEARRFNTSYVGTEHILLGLLREGEGVAVRILMEQGIDFNRVREEIVKMLNEEPAGGPAKAAKVKNTN
TPTLNQFGRDLTELARDGKLDPVIGREKEIERVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVEGEIPEILKDKRV
VTLDMASMVAGTKYRGEFEDRLKTVLNEVIKAGNVILFIDEMHTLIGAGAAEGAIDASNILKPALARGEIQVVGATTLDE
YRKYVERDPALERRFQPIIVDEPTVEETIEILKGLRDKYEAHHRVKITDEALEAAARLSHRYIADRFLPDKAIDLIDEAA
SRVRLKTVTAPPEIKELEDKINDLIKEKEEAIRTQEYEKAAKIRDEEQKLREELEKLKAKWQQNSLSNEKSVGPEEIAQV
VSLWTGIPVKKLAEEESERLLHLEEVLHERVIGQDEAVEAVARAIRRARVGLKDPKRPIGSFIFLGPTGVGKTELTKALA
EALFGDENAMIRLDMSEYMERHTVSKLIGSPPGYVGFEEGGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQILEDGRL
TDSKGRTVDFKNTVIIMTSNVGAELLKKQSTLGFMPQEKEDKASYDKIKETLMAELRKTFRPEFLNRVDEIIVFHQLSKE
DIEKIADIMIKELNDRLKENDIKLDFTPEAKEEIIKQGYDPNYGARPLRRVIQRIVENQLSELMLQGEVKPGDELIVTAK
DGKIEFVKKDAIKKA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=331, Percent_Identity=38.368580060423, Blast_Score=215, Evalue=1e-55,
Organism=Escherichia coli, GI1788943, Length=853, Percent_Identity=48.5345838218054, Blast_Score=756, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=801, Percent_Identity=39.0761548064919, Blast_Score=532, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6320464, Length=706, Percent_Identity=50.2832861189802, Blast_Score=679, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=397, Percent_Identity=42.8211586901763, Blast_Score=316, Evalue=1e-86,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 92004; Mature: 91873

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMFGRFTERAQKALYLAQEEARSFYHNYVGTEHILLGLLKEDEGIAARVLKKLGVTYET
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
TREKVLSLIGMGNIPGDVVGYTPRAKRVLELSLSEARRFNTSYVGTEHILLGLLREGEGV
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
AVRILMEQGIDFNRVREEIVKMLNEEPAGGPAKAAKVKNTNTPTLNQFGRDLTELARDGK
EEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCC
LDPVIGREKEIERVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVEGEIPEILKDKR
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VVTLDMASMVAGTKYRGEFEDRLKTVLNEVIKAGNVILFIDEMHTLIGAGAAEGAIDASN
EEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCCCHHH
ILKPALARGEIQVVGATTLDEYRKYVERDPALERRFQPIIVDEPTVEETIEILKGLRDKY
HHHHHHCCCCEEEEECCCHHHHHHHHHCCHHHHHCCCCEEECCCCHHHHHHHHHHHHHHH
EAHHRVKITDEALEAAARLSHRYIADRFLPDKAIDLIDEAASRVRLKTVTAPPEIKELED
HCCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHH
KINDLIKEKEEAIRTQEYEKAAKIRDEEQKLREELEKLKAKWQQNSLSNEKSVGPEEIAQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
VVSLWTGIPVKKLAEEESERLLHLEEVLHERVIGQDEAVEAVARAIRRARVGLKDPKRPI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFIFLGPTGVGKTELTKALAEALFGDENAMIRLDMSEYMERHTVSKLIGSPPGYVGFEE
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQILEDGRLTDSKGRTVDFKNTVIIMTS
CCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEC
NVGAELLKKQSTLGFMPQEKEDKASYDKIKETLMAELRKTFRPEFLNRVDEIIVFHQLSK
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCH
EDIEKIADIMIKELNDRLKENDIKLDFTPEAKEEIIKQGYDPNYGARPLRRVIQRIVENQ
HHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LSELMLQGEVKPGDELIVTAKDGKIEFVKKDAIKKA
HHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHCCCC
>Mature Secondary Structure 
AMFGRFTERAQKALYLAQEEARSFYHNYVGTEHILLGLLKEDEGIAARVLKKLGVTYET
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHH
TREKVLSLIGMGNIPGDVVGYTPRAKRVLELSLSEARRFNTSYVGTEHILLGLLREGEGV
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
AVRILMEQGIDFNRVREEIVKMLNEEPAGGPAKAAKVKNTNTPTLNQFGRDLTELARDGK
EEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCCC
LDPVIGREKEIERVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVEGEIPEILKDKR
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VVTLDMASMVAGTKYRGEFEDRLKTVLNEVIKAGNVILFIDEMHTLIGAGAAEGAIDASN
EEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCCCHHH
ILKPALARGEIQVVGATTLDEYRKYVERDPALERRFQPIIVDEPTVEETIEILKGLRDKY
HHHHHHCCCCEEEEECCCHHHHHHHHHCCHHHHHCCCCEEECCCCHHHHHHHHHHHHHHH
EAHHRVKITDEALEAAARLSHRYIADRFLPDKAIDLIDEAASRVRLKTVTAPPEIKELED
HCCCCEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCHHHHHHH
KINDLIKEKEEAIRTQEYEKAAKIRDEEQKLREELEKLKAKWQQNSLSNEKSVGPEEIAQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
VVSLWTGIPVKKLAEEESERLLHLEEVLHERVIGQDEAVEAVARAIRRARVGLKDPKRPI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFIFLGPTGVGKTELTKALAEALFGDENAMIRLDMSEYMERHTVSKLIGSPPGYVGFEE
CCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQILEDGRLTDSKGRTVDFKNTVIIMTS
CCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEC
NVGAELLKKQSTLGFMPQEKEDKASYDKIKETLMAELRKTFRPEFLNRVDEIIVFHQLSK
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCH
EDIEKIADIMIKELNDRLKENDIKLDFTPEAKEEIIKQGYDPNYGARPLRRVIQRIVENQ
HHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LSELMLQGEVKPGDELIVTAKDGKIEFVKKDAIKKA
HHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]