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The map label for this gene is phoP [H]

Identifier: 167039421

GI number: 167039421

Start: 792867

End: 793562

Strand: Direct

Name: phoP [H]

Synonym: Teth514_0766

Alternate gene names: 167039421

Gene position: 792867-793562 (Clockwise)

Preceding gene: 167039416

Following gene: 167039422

Centisome position: 32.27

GC content: 33.05

Gene sequence:

>696_bases
ATGGGTAAAAAGATATTTGTTGTTGATGACGAAATAAAAATACTGGAAGTTGTAAAGTCATATCTTGAACATGAGGGATT
TAGCGTTATTACCGAAACCAATGGCAATAACGTTTTAGATACATTCAAAAAAGAAAAACCAGACCTTGTTATATTGGACC
TCATGTTGCCAGGTATTTCAGGAGAGGAACTGTGTAAAAGGTTACGTCAGTTTTCCAATGTTCCGATATTGATGCTTACA
GCAAAAGTTCAAGAAAGTGATAAAATTAATGGATTTTCTATAGGTGCTGATGACTATATTACAAAACCATTCAGCCCACG
CGAATTGGTTATGAGAGTAAAAGCAATATTAAGAAGAACAACTGATGATGTGCCTCTTGCTGAAGTAATGTCTTTTAATA
ATGATGACCTTGTGGTTGATTTAAGAGCACATACAGTGAGGAAAAAGGGTGTGGTTGTAAATCTTACTCCAAATGAATTT
AAAATTTTAAAGATTCTAATTCGCAATCCAAATAGGGTCTTTACAAGAGAAGAATTAATTGAAAAAGTTATGGGATTTGA
CTATGAAGGCTATGACAGGACGATTGATGCACATATTAAAAATTTAAGACAAAAAATTGAAGACGATACGAAAAATCCAG
TGTATATTAAAACGGTGTATGGCGTTGGATATAAATTTGGTGATGGAAATGTTTAG

Upstream 100 bases:

>100_bases
CATAAGCCGTGATGTATAATATATGAAGAAAGAAATTTATCAAGCTATTTTCATACATTATTCATAATTTTACAATAAAA
TGATAAAGGATGGTTGAAAA

Downstream 100 bases:

>100_bases
AAATAATTTAAGAACAAGGACGGCTATTGTATTTATTTCAATAGCTCTTATATCGATTGTTATTGTAAGTATTACAACAA
ACATCTTAATAATAAATAGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MGKKIFVVDDEIKILEVVKSYLEHEGFSVITETNGNNVLDTFKKEKPDLVILDLMLPGISGEELCKRLRQFSNVPILMLT
AKVQESDKINGFSIGADDYITKPFSPRELVMRVKAILRRTTDDVPLAEVMSFNNDDLVVDLRAHTVRKKGVVVNLTPNEF
KILKILIRNPNRVFTREELIEKVMGFDYEGYDRTIDAHIKNLRQKIEDDTKNPVYIKTVYGVGYKFGDGNV

Sequences:

>Translated_231_residues
MGKKIFVVDDEIKILEVVKSYLEHEGFSVITETNGNNVLDTFKKEKPDLVILDLMLPGISGEELCKRLRQFSNVPILMLT
AKVQESDKINGFSIGADDYITKPFSPRELVMRVKAILRRTTDDVPLAEVMSFNNDDLVVDLRAHTVRKKGVVVNLTPNEF
KILKILIRNPNRVFTREELIEKVMGFDYEGYDRTIDAHIKNLRQKIEDDTKNPVYIKTVYGVGYKFGDGNV
>Mature_230_residues
GKKIFVVDDEIKILEVVKSYLEHEGFSVITETNGNNVLDTFKKEKPDLVILDLMLPGISGEELCKRLRQFSNVPILMLTA
KVQESDKINGFSIGADDYITKPFSPRELVMRVKAILRRTTDDVPLAEVMSFNNDDLVVDLRAHTVRKKGVVVNLTPNEFK
ILKILIRNPNRVFTREELIEKVMGFDYEGYDRTIDAHIKNLRQKIEDDTKNPVYIKTVYGVGYKFGDGNV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=42.5438596491228, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=40.174672489083, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=38.8646288209607, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=38.5650224215247, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=36.7713004484305, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=35.5263157894737, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.2608695652174, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=31.4159292035398, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=35.5855855855856, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=31.5789473684211, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.4372294372294, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=32.4324324324324, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=31.6964285714286, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=31.5315315315315, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=28.448275862069, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26410; Mature: 26279

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKIFVVDDEIKILEVVKSYLEHEGFSVITETNGNNVLDTFKKEKPDLVILDLMLPGIS
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCEEEEEEECCCCC
GEELCKRLRQFSNVPILMLTAKVQESDKINGFSIGADDYITKPFSPRELVMRVKAILRRT
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHC
TDDVPLAEVMSFNNDDLVVDLRAHTVRKKGVVVNLTPNEFKILKILIRNPNRVFTREELI
CCCCCHHHHHCCCCCCEEEEEHHHHHHHCCEEEEECCCCEEEEEEEECCCCCCCCHHHHH
EKVMGFDYEGYDRTIDAHIKNLRQKIEDDTKNPVYIKTVYGVGYKFGDGNV
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEECCCCC
>Mature Secondary Structure 
GKKIFVVDDEIKILEVVKSYLEHEGFSVITETNGNNVLDTFKKEKPDLVILDLMLPGIS
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCEEEEEEECCCCC
GEELCKRLRQFSNVPILMLTAKVQESDKINGFSIGADDYITKPFSPRELVMRVKAILRRT
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHC
TDDVPLAEVMSFNNDDLVVDLRAHTVRKKGVVVNLTPNEFKILKILIRNPNRVFTREELI
CCCCCHHHHHCCCCCCEEEEEHHHHHHHCCEEEEECCCCEEEEEEEECCCCCCCCHHHHH
EKVMGFDYEGYDRTIDAHIKNLRQKIEDDTKNPVYIKTVYGVGYKFGDGNV
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]