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The map label for this gene is carA [H]

Identifier: 167039320

GI number: 167039320

Start: 690778

End: 691848

Strand: Direct

Name: carA [H]

Synonym: Teth514_0661

Alternate gene names: 167039320

Gene position: 690778-691848 (Clockwise)

Preceding gene: 167039319

Following gene: 167039321

Centisome position: 28.11

GC content: 35.76

Gene sequence:

>1071_bases
ATGAAAGGTTATTTAAAGCTTGAGGATGGAAGCATATTTGAAGGCGAGTTAATAAGCAAAAACAAAAAAGGATATGGAGA
AGTTGTTTTTACTACAGGGATGACAGGCTATCAAGAAGCTATAACGGATCCTTCCTATGCAGGCCAAATAGTTGTCATGA
CATATCCTTTAATAGGAAATTATGGTATTAACAAATACGACTTTCAATCAGAAAAACCTCATATAAGGGGGTTTGTGATA
CGGGAATATTGTGATAAGCCTAGTAATTTCCAGAGTGAGAAGTCGCTTTTGAGCTATCTTGATGAGCACAACATACCGGT
ATTATCAGGTGTTGATACAAGGGCCTTGACAAAAAAACTTAGAGAAAATGGAACTATGAGAGGAATTATAACTTGTAACG
CTGACGACAACATAGAATTTGACCAAACAAATCTTTTAGAAGAAGTTTCTACAAAAAGGTCATACCGTATAGCGGGCATT
GGTCCAAAACTTGCCTTTATTGACCTTGGCACAAAAAAGAGTATTTTAAAAATGCTAAATTCAGTTGGATTTGACATTTA
TGTGTTTCCTTACAATGCAAGTTATGATGATGTTATGCAAATAAATCCCGATGCAATATTTCTTTCAAATGGACCGGGTG
ACCCTAAAGATGCAGTTTATGCAATAGAACTTACTAAACACTTTATAGGTATAAAACCTGTGTTGGGGATATGCCTAGGT
CATCAGATAATAGCGCTCGCTCTTGGATGCAATACAGTAAAAATGAAATTCGGCCACAGAGGTGCAAATCAACCTGTTAA
AGATTTACTGACAAATAAAGACTATATAACTTCTCAAAACCACGGATACGCTGTTGAAGAGGAATCAATAGATAAAGACA
AGATAACTGTTACCCATATAAACTTAAACGATGGAACAGTAGAAGGCATTATGCATAAGTTTCTGCCAGTTTTTTCTGTA
CAATATCATCCTGAGGCATGTCCTGGACCCCGTGATTCAACAGATATTTTTGATAAATTCATGGATATAGTCATGGTTTA
CAAAAGGAGGTCTTATTTTGCCGAAGTATAA

Upstream 100 bases:

>100_bases
AATGTCTTAAGGTTTGTTCCTCCTCTTACTGTGACAGAAGAGGAAATAGATACGGCGATAATAATACTGGATGATGTACT
TTGTGAAATGGGGTTTTAGC

Downstream 100 bases:

>100_bases
AGATATTAATAAGGTTCTGGTAATAGGCTCAGGCCCTATTATAATAGGGCAAGCCGCAGAATTTGATTATTCAGGAACCC
AGGCCTGCAAATCCTTAAAA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKGYLKLEDGSIFEGELISKNKKGYGEVVFTTGMTGYQEAITDPSYAGQIVVMTYPLIGNYGINKYDFQSEKPHIRGFVI
REYCDKPSNFQSEKSLLSYLDEHNIPVLSGVDTRALTKKLRENGTMRGIITCNADDNIEFDQTNLLEEVSTKRSYRIAGI
GPKLAFIDLGTKKSILKMLNSVGFDIYVFPYNASYDDVMQINPDAIFLSNGPGDPKDAVYAIELTKHFIGIKPVLGICLG
HQIIALALGCNTVKMKFGHRGANQPVKDLLTNKDYITSQNHGYAVEEESIDKDKITVTHINLNDGTVEGIMHKFLPVFSV
QYHPEACPGPRDSTDIFDKFMDIVMVYKRRSYFAEV

Sequences:

>Translated_356_residues
MKGYLKLEDGSIFEGELISKNKKGYGEVVFTTGMTGYQEAITDPSYAGQIVVMTYPLIGNYGINKYDFQSEKPHIRGFVI
REYCDKPSNFQSEKSLLSYLDEHNIPVLSGVDTRALTKKLRENGTMRGIITCNADDNIEFDQTNLLEEVSTKRSYRIAGI
GPKLAFIDLGTKKSILKMLNSVGFDIYVFPYNASYDDVMQINPDAIFLSNGPGDPKDAVYAIELTKHFIGIKPVLGICLG
HQIIALALGCNTVKMKFGHRGANQPVKDLLTNKDYITSQNHGYAVEEESIDKDKITVTHINLNDGTVEGIMHKFLPVFSV
QYHPEACPGPRDSTDIFDKFMDIVMVYKRRSYFAEV
>Mature_356_residues
MKGYLKLEDGSIFEGELISKNKKGYGEVVFTTGMTGYQEAITDPSYAGQIVVMTYPLIGNYGINKYDFQSEKPHIRGFVI
REYCDKPSNFQSEKSLLSYLDEHNIPVLSGVDTRALTKKLRENGTMRGIITCNADDNIEFDQTNLLEEVSTKRSYRIAGI
GPKLAFIDLGTKKSILKMLNSVGFDIYVFPYNASYDDVMQINPDAIFLSNGPGDPKDAVYAIELTKHFIGIKPVLGICLG
HQIIALALGCNTVKMKFGHRGANQPVKDLLTNKDYITSQNHGYAVEEESIDKDKITVTHINLNDGTVEGIMHKFLPVFSV
QYHPEACPGPRDSTDIFDKFMDIVMVYKRRSYFAEV

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=359, Percent_Identity=42.0612813370474, Blast_Score=271, Evalue=7e-73,
Organism=Homo sapiens, GI21361331, Length=360, Percent_Identity=36.3888888888889, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI169790915, Length=360, Percent_Identity=36.3888888888889, Blast_Score=223, Evalue=3e-58,
Organism=Escherichia coli, GI1786215, Length=376, Percent_Identity=44.1489361702128, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1789760, Length=153, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193204318, Length=372, Percent_Identity=39.7849462365591, Blast_Score=266, Evalue=9e-72,
Organism=Saccharomyces cerevisiae, GI6324878, Length=372, Percent_Identity=40.3225806451613, Blast_Score=272, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6322331, Length=392, Percent_Identity=37.2448979591837, Blast_Score=243, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24642586, Length=376, Percent_Identity=40.9574468085106, Blast_Score=261, Evalue=6e-70,
Organism=Drosophila melanogaster, GI45555749, Length=376, Percent_Identity=40.9574468085106, Blast_Score=261, Evalue=7e-70,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 39908; Mature: 39908

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGYLKLEDGSIFEGELISKNKKGYGEVVFTTGMTGYQEAITDPSYAGQIVVMTYPLIGN
CCCEEEECCCCEECCHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEEEEEEECC
YGINKYDFQSEKPHIRGFVIREYCDKPSNFQSEKSLLSYLDEHNIPVLSGVDTRALTKKL
CCCCCCCCCCCCCCHHEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHH
RENGTMRGIITCNADDNIEFDQTNLLEEVSTKRSYRIAGIGPKLAFIDLGTKKSILKMLN
HHCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHH
SVGFDIYVFPYNASYDDVMQINPDAIFLSNGPGDPKDAVYAIELTKHFIGIKPVLGICLG
HCCCEEEEEEECCCCCCEEEECCCEEEEECCCCCCCCCEEEEEEHHHHHCHHHHHHHHHH
HQIIALALGCNTVKMKFGHRGANQPVKDLLTNKDYITSQNHGYAVEEESIDKDKITVTHI
HHHHHHHHCCCEEEEEECCCCCCCCHHHHHCCCCEEECCCCCEEECCCCCCCCCEEEEEE
NLNDGTVEGIMHKFLPVFSVQYHPEACPGPRDSTDIFDKFMDIVMVYKRRSYFAEV
ECCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGYLKLEDGSIFEGELISKNKKGYGEVVFTTGMTGYQEAITDPSYAGQIVVMTYPLIGN
CCCEEEECCCCEECCHHHCCCCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEEEEEEECC
YGINKYDFQSEKPHIRGFVIREYCDKPSNFQSEKSLLSYLDEHNIPVLSGVDTRALTKKL
CCCCCCCCCCCCCCHHEEEEHHHCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHH
RENGTMRGIITCNADDNIEFDQTNLLEEVSTKRSYRIAGIGPKLAFIDLGTKKSILKMLN
HHCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHH
SVGFDIYVFPYNASYDDVMQINPDAIFLSNGPGDPKDAVYAIELTKHFIGIKPVLGICLG
HCCCEEEEEEECCCCCCEEEECCCEEEEECCCCCCCCCEEEEEEHHHHHCHHHHHHHHHH
HQIIALALGCNTVKMKFGHRGANQPVKDLLTNKDYITSQNHGYAVEEESIDKDKITVTHI
HHHHHHHHCCCEEEEEECCCCCCCCHHHHHCCCCEEECCCCCEEECCCCCCCCCEEEEEE
NLNDGTVEGIMHKFLPVFSVQYHPEACPGPRDSTDIFDKFMDIVMVYKRRSYFAEV
ECCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]