Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 167039319

GI number: 167039319

Start: 689592

End: 690776

Strand: Direct

Name: argD [H]

Synonym: Teth514_0660

Alternate gene names: 167039319

Gene position: 689592-690776 (Clockwise)

Preceding gene: 167039318

Following gene: 167039320

Centisome position: 28.06

GC content: 37.89

Gene sequence:

>1185_bases
ATGATAACCTTTGAGGATAAGAAATATCTAATGAATACTTATAGCAGATACCCTATTACCTTGGTAGAGGGAAAAGGGAC
AAAAGTATGGGATGACAAAGGAAATGTCTATCTGGATTTTATTGCAGGTATTGCAGTAAATTCACTGGGGCACTGTCATC
CAGCATTAGTTAATGCTCTAAAGAATCAATCTGAAAAACTTATACACTGTTCTAATCTTTATTGGAATGAGAATCAAATA
GAACTTGCAAAGATAATTGCGGAAAATTCATTTGGAGGCAAAGTATTTTTTGCAAATAGTGGCGCAGAAGCAAATGAAGG
TGCTATAAAACTTGCTAGAAAATATGCATCATTAAAGTACGGTGATAAAAGGCATAAGGTTATATCTGCCAAAAATTCTT
TTCATGGAAGAACTTTTGGGGCATTGACAGCGACAGGCCAAGAAAAGTATCACAAGGGTTTTGGACCACTTCTTTCTGGT
TTTAAATATGTACCTTTTAATGATATTGACGCTCTTTATGAAGCAATTGATGATGAAGTGTGTGCAATTATGCTGGAAGT
AGTGCAAGGCGAAGGTGGTATCCATGAAGCTACACCGGAGTATATAAAGGCAGTAAGAGAAATATGTGATGAAAATGACA
TCCTCTTTATAATAGACGAAGTTCAGACAGGTATAGGAAGGACGGGAAAACTTTTTGGATATGAGCATTACGGTATAACT
CCTGACATTATGACTTTGGCAAAGGGATTGGGAGGGGGGTTCCCAATAGGAGCTATTGTCGCAAAAGAAGATAAATCAGT
TTTTTCACCAGGAGACCATGCCTCCACATTTGGCGGAAATCCTTTAGCTTGTGCTGCAGGGATTGCGGTTATGAAAGAAA
TAACAAAGGAAGGTTTTCTAGATAGTGTGGCTCAAAAAGGTGAGTATTTCAAGGGAAAACTTGAAAGTTTAAAGGAGAAA
CACAGTGTCATAAAAGAGGTGAGAGGGAAAGGACTTATGATAGGCTGCGAAATGGATATGGAAGAGGCTTCGGATATTGT
GACAAAGGCGATGGGAAAAGGCTTACTTATAAATTGTATCAGTCACAATGTCTTAAGGTTTGTTCCTCCTCTTACTGTGA
CAGAAGAGGAAATAGATACGGCGATAATAATACTGGATGATGTACTTTGTGAAATGGGGTTTTAG

Upstream 100 bases:

>100_bases
AGAGCTCACATCATTGACGGAAGGCTTACACATTCACTACTTCTTGAAATTTTTACTGATGAAGGCATAGGTACTATGAT
AGGAAAGGAATGTTTTGACG

Downstream 100 bases:

>100_bases
CATGAAAGGTTATTTAAAGCTTGAGGATGGAAGCATATTTGAAGGCGAGTTAATAAGCAAAAACAAAAAAGGATATGGAG
AAGTTGTTTTTACTACAGGG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MITFEDKKYLMNTYSRYPITLVEGKGTKVWDDKGNVYLDFIAGIAVNSLGHCHPALVNALKNQSEKLIHCSNLYWNENQI
ELAKIIAENSFGGKVFFANSGAEANEGAIKLARKYASLKYGDKRHKVISAKNSFHGRTFGALTATGQEKYHKGFGPLLSG
FKYVPFNDIDALYEAIDDEVCAIMLEVVQGEGGIHEATPEYIKAVREICDENDILFIIDEVQTGIGRTGKLFGYEHYGIT
PDIMTLAKGLGGGFPIGAIVAKEDKSVFSPGDHASTFGGNPLACAAGIAVMKEITKEGFLDSVAQKGEYFKGKLESLKEK
HSVIKEVRGKGLMIGCEMDMEEASDIVTKAMGKGLLINCISHNVLRFVPPLTVTEEEIDTAIIILDDVLCEMGF

Sequences:

>Translated_394_residues
MITFEDKKYLMNTYSRYPITLVEGKGTKVWDDKGNVYLDFIAGIAVNSLGHCHPALVNALKNQSEKLIHCSNLYWNENQI
ELAKIIAENSFGGKVFFANSGAEANEGAIKLARKYASLKYGDKRHKVISAKNSFHGRTFGALTATGQEKYHKGFGPLLSG
FKYVPFNDIDALYEAIDDEVCAIMLEVVQGEGGIHEATPEYIKAVREICDENDILFIIDEVQTGIGRTGKLFGYEHYGIT
PDIMTLAKGLGGGFPIGAIVAKEDKSVFSPGDHASTFGGNPLACAAGIAVMKEITKEGFLDSVAQKGEYFKGKLESLKEK
HSVIKEVRGKGLMIGCEMDMEEASDIVTKAMGKGLLINCISHNVLRFVPPLTVTEEEIDTAIIILDDVLCEMGF
>Mature_394_residues
MITFEDKKYLMNTYSRYPITLVEGKGTKVWDDKGNVYLDFIAGIAVNSLGHCHPALVNALKNQSEKLIHCSNLYWNENQI
ELAKIIAENSFGGKVFFANSGAEANEGAIKLARKYASLKYGDKRHKVISAKNSFHGRTFGALTATGQEKYHKGFGPLLSG
FKYVPFNDIDALYEAIDDEVCAIMLEVVQGEGGIHEATPEYIKAVREICDENDILFIIDEVQTGIGRTGKLFGYEHYGIT
PDIMTLAKGLGGGFPIGAIVAKEDKSVFSPGDHASTFGGNPLACAAGIAVMKEITKEGFLDSVAQKGEYFKGKLESLKEK
HSVIKEVRGKGLMIGCEMDMEEASDIVTKAMGKGLLINCISHNVLRFVPPLTVTEEEIDTAIIILDDVLCEMGF

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=35.6410256410256, Blast_Score=258, Evalue=6e-69,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.4515050167224, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=29.5454545454545, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI37574042, Length=415, Percent_Identity=30.3614457831325, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI226442709, Length=384, Percent_Identity=30.2083333333333, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=26.0765550239234, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=29.1566265060241, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=24.009324009324, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=24.009324009324, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=24.009324009324, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1788044, Length=386, Percent_Identity=42.7461139896373, Blast_Score=350, Evalue=8e-98,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=43.8320209973753, Blast_Score=349, Evalue=1e-97,
Organism=Escherichia coli, GI145693181, Length=388, Percent_Identity=37.8865979381443, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1789016, Length=408, Percent_Identity=35.5392156862745, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1787560, Length=392, Percent_Identity=37.7551020408163, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1786991, Length=311, Percent_Identity=31.8327974276527, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786349, Length=318, Percent_Identity=28.9308176100629, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=387, Percent_Identity=35.9173126614987, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI32564660, Length=429, Percent_Identity=34.2657342657343, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI25144274, Length=268, Percent_Identity=36.9402985074627, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=30.3030303030303, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71981843, Length=167, Percent_Identity=34.7305389221557, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=443, Percent_Identity=25.9593679458239, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=39.440203562341, Blast_Score=283, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=400, Percent_Identity=35.75, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6324386, Length=372, Percent_Identity=28.2258064516129, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=422, Percent_Identity=26.0663507109005, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357415, Length=398, Percent_Identity=33.6683417085427, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI161085790, Length=429, Percent_Identity=32.1678321678322, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI28574759, Length=431, Percent_Identity=32.2505800464037, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=28.2660332541568, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=28.4688995215311, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=28.4688995215311, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=28.4688995215311, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43085; Mature: 43085

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFEDKKYLMNTYSRYPITLVEGKGTKVWDDKGNVYLDFIAGIAVNSLGHCHPALVNAL
CCCCCCHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEEEHHHHHHHCCCCCCHHHHHHH
KNQSEKLIHCSNLYWNENQIELAKIIAENSFGGKVFFANSGAEANEGAIKLARKYASLKY
HCCCCCEEEECCCEECCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
GDKRHKVISAKNSFHGRTFGALTATGQEKYHKGFGPLLSGFKYVPFNDIDALYEAIDDEV
CCCHHHEEECCCCCCCCEEEEEEECCHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHH
CAIMLEVVQGEGGIHEATPEYIKAVREICDENDILFIIDEVQTGIGRTGKLFGYEHYGIT
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEECCCCC
PDIMTLAKGLGGGFPIGAIVAKEDKSVFSPGDHASTFGGNPLACAAGIAVMKEITKEGFL
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DSVAQKGEYFKGKLESLKEKHSVIKEVRGKGLMIGCEMDMEEASDIVTKAMGKGLLINCI
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEHHH
SHNVLRFVPPLTVTEEEIDTAIIILDDVLCEMGF
HHHHHHHCCCCCEEHHHHCEEEEEHHHHHHHCCC
>Mature Secondary Structure
MITFEDKKYLMNTYSRYPITLVEGKGTKVWDDKGNVYLDFIAGIAVNSLGHCHPALVNAL
CCCCCCHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEEEHHHHHHHCCCCCCHHHHHHH
KNQSEKLIHCSNLYWNENQIELAKIIAENSFGGKVFFANSGAEANEGAIKLARKYASLKY
HCCCCCEEEECCCEECCCHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
GDKRHKVISAKNSFHGRTFGALTATGQEKYHKGFGPLLSGFKYVPFNDIDALYEAIDDEV
CCCHHHEEECCCCCCCCEEEEEEECCHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHH
CAIMLEVVQGEGGIHEATPEYIKAVREICDENDILFIIDEVQTGIGRTGKLFGYEHYGIT
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHCCCCCCCEEEEECCCCC
PDIMTLAKGLGGGFPIGAIVAKEDKSVFSPGDHASTFGGNPLACAAGIAVMKEITKEGFL
HHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DSVAQKGEYFKGKLESLKEKHSVIKEVRGKGLMIGCEMDMEEASDIVTKAMGKGLLINCI
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCEEHHH
SHNVLRFVPPLTVTEEEIDTAIIILDDVLCEMGF
HHHHHHHCCCCCEEHHHHCEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]