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The map label for this gene is argB [H]

Identifier: 167039318

GI number: 167039318

Start: 688706

End: 689605

Strand: Direct

Name: argB [H]

Synonym: Teth514_0659

Alternate gene names: 167039318

Gene position: 688706-689605 (Clockwise)

Preceding gene: 167039317

Following gene: 167039319

Centisome position: 28.03

GC content: 38.89

Gene sequence:

>900_bases
ATGATTAGAAGGCAAAAATATGGCGACGAAATCGCAAAAGCCCAGGTTTTAATAGAAGCACTCCCATACATTAAAAAGTT
CTCCGGCACGACAGTTGTAATAAAATACGGTGGAAGTGCAATGTTAGACTGCAATTTAAAAAGAATGGTAATGCAGGACA
TTGTATTGATGAAATTTGTAGGATTAAATCCTATAGTTGTACATGGCGGTGGACCAGAAATAAATAAGATGCTGGAGAGG
CTAGGTATAGAATCAAAGTTTGTAAATGGCTTGAGGGTTACCGACGAGGCCACGATGGAGATTGTTGAAATGGTGCTGAC
AGGTCGTATCAACAAAGAAATTGTATCCTTGATCAATGAACTAGGGGGCCAGGCGATTGGCGTAAGCGGGAAAGATGGGA
GACTTTTAAAGGCGGAAAAAGATACCTCAAACGGCGACATAGGATACGTAGGAAAAATTGTAGATGTAAACATAGATGTA
ATAACAATGATGCTGGAAAAAGGATATATACCTGTTATTGCACCGACATCTTTCGGAGATGACGGCAAAACATACAATGT
GAATGCAGATACTGCCGCGGGGAAAATTGCAGAAGCATTAAAGGCTGAAAAGCTAATTTTACTTACGGATGTCGAAGGAA
TTCTATCAAATATAAACGATAAAAGCAGCCTAATATCCCGAATGGACTTAGAGCATGCAAAAGAATTTATGAATTCGGGA
CGCATAAACGGTGGGATGATACCAAAACTTGAATGTTGCATAAAAGCTGTTGAAAATGGTGTAAAAAGAGCTCACATCAT
TGACGGAAGGCTTACACATTCACTACTTCTTGAAATTTTTACTGATGAAGGCATAGGTACTATGATAGGAAAGGAATGTT
TTGACGATGATAACCTTTGA

Upstream 100 bases:

>100_bases
TTACTGTAACCGTAGATATGAAGGCCGGGGAATATAGCGGAACTGCGTGGGGGTGCGACTTAAGCTATGACTATGTAAAA
ATTAACGGGAGTTATAGAAC

Downstream 100 bases:

>100_bases
GGATAAGAAATATCTAATGAATACTTATAGCAGATACCCTATTACCTTGGTAGAGGGAAAAGGGACAAAAGTATGGGATG
ACAAAGGAAATGTCTATCTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MIRRQKYGDEIAKAQVLIEALPYIKKFSGTTVVIKYGGSAMLDCNLKRMVMQDIVLMKFVGLNPIVVHGGGPEINKMLER
LGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINELGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDV
ITMMLEKGYIPVIAPTSFGDDGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSG
RINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL

Sequences:

>Translated_299_residues
MIRRQKYGDEIAKAQVLIEALPYIKKFSGTTVVIKYGGSAMLDCNLKRMVMQDIVLMKFVGLNPIVVHGGGPEINKMLER
LGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINELGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDV
ITMMLEKGYIPVIAPTSFGDDGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSG
RINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL
>Mature_299_residues
MIRRQKYGDEIAKAQVLIEALPYIKKFSGTTVVIKYGGSAMLDCNLKRMVMQDIVLMKFVGLNPIVVHGGGPEINKMLER
LGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINELGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDV
ITMMLEKGYIPVIAPTSFGDDGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSG
RINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=280, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI145693208, Length=225, Percent_Identity=32, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=274, Percent_Identity=30.6569343065693, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR003964 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 32576; Mature: 32576

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRQKYGDEIAKAQVLIEALPYIKKFSGTTVVIKYGGSAMLDCNLKRMVMQDIVLMKFV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHC
GLNPIVVHGGGPEINKMLERLGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINE
CCCEEEEECCCHHHHHHHHHHCCHHHHHCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHH
LGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDVITMMLEKGYIPVIAPTSFGD
HCCCEEECCCCCCCEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEECCCCCC
DGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSG
CCCEEECCCCHHHHHHHHHHHHCCEEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
RINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL
CCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MIRRQKYGDEIAKAQVLIEALPYIKKFSGTTVVIKYGGSAMLDCNLKRMVMQDIVLMKFV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCHHHHHHHHHHHHHHC
GLNPIVVHGGGPEINKMLERLGIESKFVNGLRVTDEATMEIVEMVLTGRINKEIVSLINE
CCCEEEEECCCHHHHHHHHHHCCHHHHHCCEEECHHHHHHHHHHHHHCCCCHHHHHHHHH
LGGQAIGVSGKDGRLLKAEKDTSNGDIGYVGKIVDVNIDVITMMLEKGYIPVIAPTSFGD
HCCCEEECCCCCCCEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEECCCCCC
DGKTYNVNADTAAGKIAEALKAEKLILLTDVEGILSNINDKSSLISRMDLEHAKEFMNSG
CCCEEECCCCHHHHHHHHHHHHCCEEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
RINGGMIPKLECCIKAVENGVKRAHIIDGRLTHSLLLEIFTDEGIGTMIGKECFDDDNL
CCCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA