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The map label for this gene is prsA [H]

Identifier: 167039253

GI number: 167039253

Start: 618562

End: 619467

Strand: Direct

Name: prsA [H]

Synonym: Teth514_0594

Alternate gene names: 167039253

Gene position: 618562-619467 (Clockwise)

Preceding gene: 167039252

Following gene: 167039254

Centisome position: 25.17

GC content: 29.91

Gene sequence:

>906_bases
TTGAAGAGGAAAATTGCATTACTTTTATCTTTCGTTTTTATAGTATTTTTAACAGTATCGTGTTCTGCCGAAAAAGACGT
GGTAGCAGTTGTCAACGGTGAAAATATAACTAATGCGGAATATAAAAAAGTTTTTGACCAAGTAAAGGCACAAATTGAAA
GTAGTCCCCAATATACAAAAGATATATGGGATGAGGATTATCAAGGGAAAAAGTTTTTAGATGTAGTAAAAGAAAATGTG
CTTGATAGTTTAATTGCTGAAAAATTGCTTGTGCAAGAAGCTCTAAAAAATAATATTACAGTTACAGATAAAGAAATAGA
GGATGAATATCAAAAACAAAAAGAAGTTAATAAAGATATTACAAAGGAAGATGTGAAAAATTATCTTTTAATAAATAAGC
TCTTTGACGAATATACAAAAGATGTAAAAGTTACAGAAGAAGAGTTAAAAAAGTATTATGAGGATAATGAAGAGCAATTC
GAAACAGTGAAGGCTAGTCATATATTAGTGGTTGATGAAAAAACAGCAGAAGATATATACAATCGACTTATGAAAGGCGA
AGATTTTGCTACATTAGCAAAAGAGTATTCTGTTGATACGGCTACAAAAGACCAAGGAGGAGATCTGGGAGAATTTCCTC
ATGGCGTTATGGTTCCAGAGTTTGACCAAGTAGTTTTTTCACTTAAGAAAGGTGAAATATCAAAACCTGTTAAGACTGAT
TATGGATACCATATAATAAAGTCAGATGGTGTTATAATAAAACCTTTTGATGAAGTAAAAGATACTATAGAAAGTTATTT
GTTAGATGATAAGAAAAATCAAGTTATTATAGAAAAATATGATGCCCTTGAGAAAGCAGCAAAAATACAAAAGTTTCCTC
AAAACATAAAAGTAACAGTAGGATAA

Upstream 100 bases:

>100_bases
TTGAATTGGTAGAAAAAATAAAAAGTTTGCAGTGAGGATAAAAATGATATATAATTAAATTATGCCCATGTAAACTTTTT
AAAGTCAGGAGGATGTCATT

Downstream 100 bases:

>100_bases
AAAAGCCGGCAATTTAGTTGCCGGTCTTTTTTTTGCGAATAAATTTATGGAAAAATATAAATACTAATCTTGAGCTAAAA
ATTTTAGGAAATGGAGGTAT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKRKIALLLSFVFIVFLTVSCSAEKDVVAVVNGENITNAEYKKVFDQVKAQIESSPQYTKDIWDEDYQGKKFLDVVKENV
LDSLIAEKLLVQEALKNNITVTDKEIEDEYQKQKEVNKDITKEDVKNYLLINKLFDEYTKDVKVTEEELKKYYEDNEEQF
ETVKASHILVVDEKTAEDIYNRLMKGEDFATLAKEYSVDTATKDQGGDLGEFPHGVMVPEFDQVVFSLKKGEISKPVKTD
YGYHIIKSDGVIIKPFDEVKDTIESYLLDDKKNQVIIEKYDALEKAAKIQKFPQNIKVTVG

Sequences:

>Translated_301_residues
MKRKIALLLSFVFIVFLTVSCSAEKDVVAVVNGENITNAEYKKVFDQVKAQIESSPQYTKDIWDEDYQGKKFLDVVKENV
LDSLIAEKLLVQEALKNNITVTDKEIEDEYQKQKEVNKDITKEDVKNYLLINKLFDEYTKDVKVTEEELKKYYEDNEEQF
ETVKASHILVVDEKTAEDIYNRLMKGEDFATLAKEYSVDTATKDQGGDLGEFPHGVMVPEFDQVVFSLKKGEISKPVKTD
YGYHIIKSDGVIIKPFDEVKDTIESYLLDDKKNQVIIEKYDALEKAAKIQKFPQNIKVTVG
>Mature_301_residues
MKRKIALLLSFVFIVFLTVSCSAEKDVVAVVNGENITNAEYKKVFDQVKAQIESSPQYTKDIWDEDYQGKKFLDVVKENV
LDSLIAEKLLVQEALKNNITVTDKEIEDEYQKQKEVNKDITKEDVKNYLLINKLFDEYTKDVKVTEEELKKYYEDNEEQF
ETVKASHILVVDEKTAEDIYNRLMKGEDFATLAKEYSVDTATKDQGGDLGEFPHGVMVPEFDQVVFSLKKGEISKPVKTD
YGYHIIKSDGVIIKPFDEVKDTIESYLLDDKKNQVIIEKYDALEKAAKIQKFPQNIKVTVG

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=87, Percent_Identity=50.5747126436782, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786645, Length=269, Percent_Identity=25.2788104089219, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34600; Mature: 34600

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKIALLLSFVFIVFLTVSCSAEKDVVAVVNGENITNAEYKKVFDQVKAQIESSPQYTK
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHH
DIWDEDYQGKKFLDVVKENVLDSLIAEKLLVQEALKNNITVTDKEIEDEYQKQKEVNKDI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCC
TKEDVKNYLLINKLFDEYTKDVKVTEEELKKYYEDNEEQFETVKASHILVVDEKTAEDIY
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCEEEEECCHHHHHHH
NRLMKGEDFATLAKEYSVDTATKDQGGDLGEFPHGVMVPEFDQVVFSLKKGEISKPVKTD
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
YGYHIIKSDGVIIKPFDEVKDTIESYLLDDKKNQVIIEKYDALEKAAKIQKFPQNIKVTV
CCEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
G
C
>Mature Secondary Structure
MKRKIALLLSFVFIVFLTVSCSAEKDVVAVVNGENITNAEYKKVFDQVKAQIESSPQYTK
CCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHH
DIWDEDYQGKKFLDVVKENVLDSLIAEKLLVQEALKNNITVTDKEIEDEYQKQKEVNKDI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCC
TKEDVKNYLLINKLFDEYTKDVKVTEEELKKYYEDNEEQFETVKASHILVVDEKTAEDIY
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCEEEEECCHHHHHHH
NRLMKGEDFATLAKEYSVDTATKDQGGDLGEFPHGVMVPEFDQVVFSLKKGEISKPVKTD
HHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
YGYHIIKSDGVIIKPFDEVKDTIESYLLDDKKNQVIIEKYDALEKAAKIQKFPQNIKVTV
CCEEEEECCCEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]