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The map label for this gene is licA [H]

Identifier: 167039194

GI number: 167039194

Start: 553632

End: 553946

Strand: Direct

Name: licA [H]

Synonym: Teth514_0535

Alternate gene names: 167039194

Gene position: 553632-553946 (Clockwise)

Preceding gene: 167039193

Following gene: 167039195

Centisome position: 22.53

GC content: 33.97

Gene sequence:

>315_bases
ATGGACTTAGAACAAATAATATACAATTTAGTATTACATGGAGGAAATGCAAGAGCAGAAGCTTATGAAGCATTGGATGC
AGCTGAAAGAGGAGATTTTGAGGAAGCAGAAAGGCATCTTGAAAAAGCAGATGAAGAGTTTTATGAAGGGCATAAATACC
AAAATATGCTTACACAAGGAGAGCAAAGTGAAGCTCCTAATTTTCTAGTAATTCACGCTCAAGACCAGCTTATGACAGCC
CTTGCTGAAAAAAATTTAATAAAAAGAATGATTGAGCTCTATAAAAGAGTCAATCAATTAGAAAAAAGACAATAA

Upstream 100 bases:

>100_bases
GATTATATACTATCCCTTCTTTAAAATGTATGAAGCTCAACTTTTAAAGAACGAAAAAGGAGTAAAAGACCAAGAATAAT
TTGTGATGGGAGTGAAACTA

Downstream 100 bases:

>100_bases
TAAAATCCCCTCGCTACCCGGAAATTCCGGGTAGTATTTTTATAATAATTATATCACCTTGTTTCTTTTTTGTCATTATG
ACCCGAAGCTTTGAAAGTCA

Product: PTS system lactose/cellobiose-specific IIA subunit

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MDLEQIIYNLVLHGGNARAEAYEALDAAERGDFEEAERHLEKADEEFYEGHKYQNMLTQGEQSEAPNFLVIHAQDQLMTA
LAEKNLIKRMIELYKRVNQLEKRQ

Sequences:

>Translated_104_residues
MDLEQIIYNLVLHGGNARAEAYEALDAAERGDFEEAERHLEKADEEFYEGHKYQNMLTQGEQSEAPNFLVIHAQDQLMTA
LAEKNLIKRMIELYKRVNQLEKRQ
>Mature_104_residues
MDLEQIIYNLVLHGGNARAEAYEALDAAERGDFEEAERHLEKADEEFYEGHKYQNMLTQGEQSEAPNFLVIHAQDQLMTA
LAEKNLIKRMIELYKRVNQLEKRQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=99, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 12152; Mature: 12152

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEQIIYNLVLHGGNARAEAYEALDAAERGDFEEAERHLEKADEEFYEGHKYQNMLTQG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQSEAPNFLVIHAQDQLMTALAEKNLIKRMIELYKRVNQLEKRQ
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLEQIIYNLVLHGGNARAEAYEALDAAERGDFEEAERHLEKADEEFYEGHKYQNMLTQG
CCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQSEAPNFLVIHAQDQLMTALAEKNLIKRMIELYKRVNQLEKRQ
CCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]