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The map label for this gene is ywbA [H]

Identifier: 167039193

GI number: 167039193

Start: 552294

End: 553610

Strand: Direct

Name: ywbA [H]

Synonym: Teth514_0534

Alternate gene names: 167039193

Gene position: 552294-553610 (Clockwise)

Preceding gene: 167039192

Following gene: 167039194

Centisome position: 22.48

GC content: 37.66

Gene sequence:

>1317_bases
ATGAACGATAGGCTTTCAAACAATTGGTTTATGAAGTGGATGGAAGAATCTTTAATGCCAGTTCTTGCTCGTATAGCGCA
AAATGTGTATTTGCAGTCAATTAGAGACGCATTTTCAAGCTTTGCTTTGCCTGTGATTTTGACTGGTGCCCTTTTCTTAA
TTATAGCAAATCCACCAGAGGGAATTAATTGGGCACCTATACATGCATGGGCAAGAGCAGTAAAACCTATTGCAGCTCAA
ATCATGATACCTTTCCAACTTACTTTTGGGATAATGGCTATGATGGTAGCCTTTGGTACAGCTTATAGCCTTGCTACACG
ATGGGACCTCGACGAGACGATGACAGGAATTATTTCAATGTTGGCATTTTTTATAACAAGCTTTCCTGCAACAGATGTGA
CAAAAGTTACTTTTGGAGATGTACTAAATTACCTCGGCGGTCAAGGTTTGTTTGTAGCAATAATAATAGGCATAATTACG
GCAATAGTTGTGAGATTCTTTAACAAAAGTGGTTTGGTAATAAAAATGCCTGAAGGTGTGCCACCTTATGTGGTAAGAAG
CTTCTTAGCATTAGTTCCTATGTTTGTAATGATAGTGTCAGCGTGGATTGTAGAATGGATTGTATGGGCAAATTTCCATA
TGACATTGCCGCAATTGGTGCTTGACTTATTTAAGCCCCTTGTTGCTGCATCAAATAGTTATCCTGCAGCTTTAGCTGAA
ATAATACTAATGATGCTTTTGTGGTCATTAGGAATTCACGGTATGAATGTTGTTTCTTCAATTGCTTATCCTTTCTGGAT
GACTCAATTAGCTGCAAATGCAGAAGCTGCAGCAAAAGGGCTGCCTTTACCAGGCATTGTAACTGAACCTTTCTTCCATG
TGTTTACTCATTTAGGTGGTTCAGGTACTACATGGGCTTTGACAATAATGTTTTTACTTTCAGCTTCTGCACAACTTAGG
ACAATTGGGAGAGCTGAGCTTATACCTGCAATATTTAATATAAACGAGCCACTAATTTTTGGTACACCTATTGTGTTAAA
TCCGATACTCATTATTCCGTTTATATTAGCTCCAGCAGCTGTTGTAACAATAAATTACTTTGCTTTTGCTGTAAACTTAG
TACCAAGACCTTTAATACAATTGCCTTTTACAGTTCCAGTTTTTATAAGCGGATTTTTATCTTCCGGTGGCCACTGGCAA
GGTGCTTTGTTGCAGCTGGTAAATTTAATTGTAACAGCGATTATATACTATCCCTTCTTTAAAATGTATGAAGCTCAACT
TTTAAAGAACGAAAAAGGAGTAAAAGACCAAGAATAA

Upstream 100 bases:

>100_bases
CGACATGCAGGCCTTTGCTATGATGGATGGCAAAAAAATATTAAATCAAATAATTGAGCTTGCTAAAAAAAGTGGAAAAG
AAGTTTAAGGAGGGAATAAA

Downstream 100 bases:

>100_bases
TTTGTGATGGGAGTGAAACTAATGGACTTAGAACAAATAATATACAATTTAGTATTACATGGAGGAAATGCAAGAGCAGA
AGCTTATGAAGCATTGGATG

Product: PTS system lactose/cellobiose family IIC subunit

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNDRLSNNWFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPEGINWAPIHAWARAVKPIAAQ
IMIPFQLTFGIMAMMVAFGTAYSLATRWDLDETMTGIISMLAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGIIT
AIVVRFFNKSGLVIKMPEGVPPYVVRSFLALVPMFVMIVSAWIVEWIVWANFHMTLPQLVLDLFKPLVAASNSYPAALAE
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAAAKGLPLPGIVTEPFFHVFTHLGGSGTTWALTIMFLLSASAQLR
TIGRAELIPAIFNINEPLIFGTPIVLNPILIIPFILAPAAVVTINYFAFAVNLVPRPLIQLPFTVPVFISGFLSSGGHWQ
GALLQLVNLIVTAIIYYPFFKMYEAQLLKNEKGVKDQE

Sequences:

>Translated_438_residues
MNDRLSNNWFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPEGINWAPIHAWARAVKPIAAQ
IMIPFQLTFGIMAMMVAFGTAYSLATRWDLDETMTGIISMLAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGIIT
AIVVRFFNKSGLVIKMPEGVPPYVVRSFLALVPMFVMIVSAWIVEWIVWANFHMTLPQLVLDLFKPLVAASNSYPAALAE
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAAAKGLPLPGIVTEPFFHVFTHLGGSGTTWALTIMFLLSASAQLR
TIGRAELIPAIFNINEPLIFGTPIVLNPILIIPFILAPAAVVTINYFAFAVNLVPRPLIQLPFTVPVFISGFLSSGGHWQ
GALLQLVNLIVTAIIYYPFFKMYEAQLLKNEKGVKDQE
>Mature_438_residues
MNDRLSNNWFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPEGINWAPIHAWARAVKPIAAQ
IMIPFQLTFGIMAMMVAFGTAYSLATRWDLDETMTGIISMLAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGIIT
AIVVRFFNKSGLVIKMPEGVPPYVVRSFLALVPMFVMIVSAWIVEWIVWANFHMTLPQLVLDLFKPLVAASNSYPAALAE
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAAAKGLPLPGIVTEPFFHVFTHLGGSGTTWALTIMFLLSASAQLR
TIGRAELIPAIFNINEPLIFGTPIVLNPILIIPFILAPAAVVTINYFAFAVNLVPRPLIQLPFTVPVFISGFLSSGGHWQ
GALLQLVNLIVTAIIYYPFFKMYEAQLLKNEKGVKDQE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=452, Percent_Identity=28.9823008849558, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48317; Mature: 48317

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRLSNNWFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
GINWAPIHAWARAVKPIAAQIMIPFQLTFGIMAMMVAFGTAYSLATRWDLDETMTGIISM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGIITAIVVRFFNKSGLVIKMPEGV
HHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
PPYVVRSFLALVPMFVMIVSAWIVEWIVWANFHMTLPQLVLDLFKPLVAASNSYPAALAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAAAKGLPLPGIVTEPFFHVFTHLGG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHCCC
SGTTWALTIMFLLSASAQLRTIGRAELIPAIFNINEPLIFGTPIVLNPILIIPFILAPAA
CCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHH
VVTINYFAFAVNLVPRPLIQLPFTVPVFISGFLSSGGHWQGALLQLVNLIVTAIIYYPFF
HHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KMYEAQLLKNEKGVKDQE
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNDRLSNNWFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
GINWAPIHAWARAVKPIAAQIMIPFQLTFGIMAMMVAFGTAYSLATRWDLDETMTGIISM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGIITAIVVRFFNKSGLVIKMPEGV
HHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
PPYVVRSFLALVPMFVMIVSAWIVEWIVWANFHMTLPQLVLDLFKPLVAASNSYPAALAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAAAKGLPLPGIVTEPFFHVFTHLGG
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHCCC
SGTTWALTIMFLLSASAQLRTIGRAELIPAIFNINEPLIFGTPIVLNPILIIPFILAPAA
CCHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHH
VVTINYFAFAVNLVPRPLIQLPFTVPVFISGFLSSGGHWQGALLQLVNLIVTAIIYYPFF
HHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
KMYEAQLLKNEKGVKDQE
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]