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The map label for this gene is gcvT [H]

Identifier: 167038901

GI number: 167038901

Start: 243418

End: 244524

Strand: Reverse

Name: gcvT [H]

Synonym: Teth514_0232

Alternate gene names: 167038901

Gene position: 244524-243418 (Counterclockwise)

Preceding gene: 167038920

Following gene: 167038900

Centisome position: 9.95

GC content: 33.69

Gene sequence:

>1107_bases
TTGGATAACCTCAAAAAAACACCTCTTTTTGAACTTTACAAAAAATATAATGGAAAAATCATTGACTTTGCAGGATGGGC
TCTCCCTGTTCAGTTTGAAAGTATAATCTCTGAACACGAAGCAGTGAGAAATGCTGCAGGACTCTTTGATGTTTCTCACA
TGGGAGAAATAACTGTAAAAGGAAGAGAAGCTTTTAACTTTTTGCAAAATCTCATAACAAATGATTTGTCAAAACTAAAA
GGCAATCAAGTCCTTTATACTTTTATGTGCAATTACAATGGCGGCGTTGTAGATGACTTATTAGTCTACAAATATTCTGA
TGAACACTTCTACTTGGTTGTAAATGCGGCTAATATAGAAAAGGATTACAAATGGATGAAAGACAATAAAGGCGTATATG
AGGTAGAAATAGAAAACATTTCAGATGAAGTAGCAGAACTTGCCATACAAGGCCCAAAAGCAGAAGAAATACTTCAAAAA
CTTACAGATACTGATCTTTCAGAAATTAAATTTTTCTGCTTTAAAGACAATGTAAAAATAGCTGGAATTGAATGCCTGGT
ATCAAGAACAGGATATACGGGTGAAGATGGCTTTGAAATTTACATGCCTAATAAATACGCAGTAGAATTGTGGGAAAAAA
TAGTGGAAGTTGGAAAAGAATATGGACTTAAACCGGCAGGATTAGGGGCAAGAGATACTTTGAGATTTGAAGCAGGTTTA
CCTCTATACGGAAATGAACTTTCAGAAGAAATAACTCCTTTAGAAGCAGGTTTTGAGTTTTTCGTCAAATTTGACAAGGG
CAATTTTATCGGAAAAGATGCTCTACTAAAGCAAAAAGAAGAAGGGCTTAAGCGTAAAATCGTGGGATTTGAAATGATAG
ACAATGGAATTCCAAGACATGGTTATGAAGTGCGTGCTCACAATCAAAAAATCGGCTATGTAACAACAGGGTATTTCTCT
CCTACACTAAAGAAAAATATAGGTCTTGCATTGATTGATTCAAAATATGCCCAATTAGGAAATCAAATTGAAATTGTGAT
AAGAAATAAGCCACTTAAGGCTTTAATCATAAGCAAAAACTTTTACAAGAAAAATTATAAAAAATAG

Upstream 100 bases:

>100_bases
GAAGCTCTCAGGTCAAAAAACAGAGGAGTTGTGATGGCATATTCTCTTGTTGTGCTCATCATAACTCCTCTTTTAAATTT
TATGAAAGGGTGTGGTATGT

Downstream 100 bases:

>100_bases
GAGGTTTTTGGTATGGAAGTTTTAGAAGGCTTGTATTACTCAAAAGACCACGAATGGGTCAAAGTAGAAGGAGATAAAGC
ATACATAGGAATAACTGACT

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MDNLKKTPLFELYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVKGREAFNFLQNLITNDLSKLK
GNQVLYTFMCNYNGGVVDDLLVYKYSDEHFYLVVNAANIEKDYKWMKDNKGVYEVEIENISDEVAELAIQGPKAEEILQK
LTDTDLSEIKFFCFKDNVKIAGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIVEVGKEYGLKPAGLGARDTLRFEAGL
PLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRHGYEVRAHNQKIGYVTTGYFS
PTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKNFYKKNYKK

Sequences:

>Translated_368_residues
MDNLKKTPLFELYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVKGREAFNFLQNLITNDLSKLK
GNQVLYTFMCNYNGGVVDDLLVYKYSDEHFYLVVNAANIEKDYKWMKDNKGVYEVEIENISDEVAELAIQGPKAEEILQK
LTDTDLSEIKFFCFKDNVKIAGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIVEVGKEYGLKPAGLGARDTLRFEAGL
PLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRHGYEVRAHNQKIGYVTTGYFS
PTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKNFYKKNYKK
>Mature_368_residues
MDNLKKTPLFELYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVKGREAFNFLQNLITNDLSKLK
GNQVLYTFMCNYNGGVVDDLLVYKYSDEHFYLVVNAANIEKDYKWMKDNKGVYEVEIENISDEVAELAIQGPKAEEILQK
LTDTDLSEIKFFCFKDNVKIAGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIVEVGKEYGLKPAGLGARDTLRFEAGL
PLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRHGYEVRAHNQKIGYVTTGYFS
PTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKNFYKKNYKK

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=371, Percent_Identity=34.7708894878706, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI257796258, Length=356, Percent_Identity=34.8314606741573, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI24797151, Length=333, Percent_Identity=33.033033033033, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI257796254, Length=375, Percent_Identity=31.2, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI257796256, Length=326, Percent_Identity=33.1288343558282, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI197927446, Length=337, Percent_Identity=29.673590504451, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI21361378, Length=337, Percent_Identity=29.673590504451, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI194306651, Length=316, Percent_Identity=28.7974683544304, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789272, Length=372, Percent_Identity=38.4408602150538, Blast_Score=255, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17560118, Length=379, Percent_Identity=36.1477572559367, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI32563613, Length=318, Percent_Identity=28.9308176100629, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71994045, Length=320, Percent_Identity=26.25, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71994052, Length=320, Percent_Identity=26.25, Blast_Score=127, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6320222, Length=396, Percent_Identity=33.8383838383838, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI20129441, Length=378, Percent_Identity=35.4497354497354, Blast_Score=217, Evalue=9e-57,
Organism=Drosophila melanogaster, GI28571104, Length=286, Percent_Identity=32.5174825174825, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI20130091, Length=348, Percent_Identity=27.0114942528736, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 41900; Mature: 41900

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLKKTPLFELYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVK
CCCCCCCCHHHHHHHHCCEEEEECCCEECCHHHHHHHHHHHHHHHHCCEECCCCCCEEEC
GREAFNFLQNLITNDLSKLKGNQVLYTFMCNYNGGVVDDLLVYKYSDEHFYLVVNAANIE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCEEEEEEEECCCC
KDYKWMKDNKGVYEVEIENISDEVAELAIQGPKAEEILQKLTDTDLSEIKFFCFKDNVKI
HHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHEEEEEEECCCEE
AGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIVEVGKEYGLKPAGLGARDTLRFEAGL
EEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
PLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRH
CCCCCHHHHHCCCHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GYEVRAHNQKIGYVTTGYFSPTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKN
CEEEEECCCEEEEEEECCCCCHHHHCCCEEEEECHHHHCCCEEEEEEECCCEEEEEEECH
FYKKNYKK
HHHCCCCC
>Mature Secondary Structure
MDNLKKTPLFELYKKYNGKIIDFAGWALPVQFESIISEHEAVRNAAGLFDVSHMGEITVK
CCCCCCCCHHHHHHHHCCEEEEECCCEECCHHHHHHHHHHHHHHHHCCEECCCCCCEEEC
GREAFNFLQNLITNDLSKLKGNQVLYTFMCNYNGGVVDDLLVYKYSDEHFYLVVNAANIE
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCEEEEEEEECCCC
KDYKWMKDNKGVYEVEIENISDEVAELAIQGPKAEEILQKLTDTDLSEIKFFCFKDNVKI
HHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHEEEEEEECCCEE
AGIECLVSRTGYTGEDGFEIYMPNKYAVELWEKIVEVGKEYGLKPAGLGARDTLRFEAGL
EEEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
PLYGNELSEEITPLEAGFEFFVKFDKGNFIGKDALLKQKEEGLKRKIVGFEMIDNGIPRH
CCCCCHHHHHCCCHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GYEVRAHNQKIGYVTTGYFSPTLKKNIGLALIDSKYAQLGNQIEIVIRNKPLKALIISKN
CEEEEECCCEEEEEEECCCCCHHHHCCCEEEEECHHHHCCCEEEEEEECCCEEEEEEECH
FYKKNYKK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA