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The map label for this gene is uxaA [H]

Identifier: 167038799

GI number: 167038799

Start: 121898

End: 123067

Strand: Direct

Name: uxaA [H]

Synonym: Teth514_0126

Alternate gene names: 167038799

Gene position: 121898-123067 (Clockwise)

Preceding gene: 167038798

Following gene: 167038800

Centisome position: 4.96

GC content: 32.91

Gene sequence:

>1170_bases
ATGAAAATTAAGGCATACAAAAGACCAGATGGTAAATATGGAATAAGAAATAAAGTTTTAATTTTACCTTCTGTAGGATG
TGCAAATGAAACAGCGAGATTAATATCAGAACAAGTTCAAGGTACGACATATATAACTAATCCAAAGGGATGCGGGCAAA
TTGGAAGTAGCGTGGAACTTATGCACAGGACTTTAATAGGGTTGACTTTAAATCCTAACGTATATGGAACCATTATAGTT
GGATTGGGATGTGAAACTATTCAAGCTTATGATTTATATGAAGAAGTTAAAAAAAGGAGTAATAAACCAGTAGAAGTCAT
AAGTATACAAAGAGAGGGAGGAACACTAAAAACCATACAGAAGGGAATTAAATTAGCACGAAAAATGGTAGAAGAGATGT
CAAAAATAGAGCGTGAAGAAGTTGACATTTCTAATATAACATTAGCAACTAATTGTGGAGGTTCTGATGCTACTTCTGGA
ATAGCTGCTAATCCAACATTAGGATATTGCAGTGATATTTTAATAAAAGAAGGGGCTACAGTATTTTTGGGTGAGACTAC
AGAATTCATTGGAGCGGAACATATATTAGCCAGAAGAGCAAAAAATGAAAAAGTTAGGAATAACTTATTAACAATAGTTA
AAAATTTAGAAAACGAGTTTATTAGATTAGGAATAGATGTTAGGGGCGCGAATCCTTCACCGGGAAATATTAAAGGAGGA
TTGAGTACTTTAGAAGAAAAATCATTAGGTTCGATTATGAAAGGTGGAACAAGTATTATTAATGAAGTTGTACGTTATGG
AGAAATTCCGAAAGAAAAAGGTCTCATTATAATGGATACACCAGGTTATGATATTGAATCTGTTACGGGGATGGTAGCTG
GAGGAGCGCAGATATGTGTATTTACCACAGGGAGAGGTACTCCTATTGGTAATCCTATTATACCTTTAATTAAAATAACG
GGAAATAAACAAACGTATGAAAACATGTCGGATAATATTGATTTAGATGTTTCGGATATAATTGAAGGTAAAAAAGACAT
TAAAGAATGTGGTGAAATGCTTTTACAAGAGATAATAGATGTATGTAATGGTAAATTAACAAAAGCAGAGATATATGGAT
TTTCAGAAACGTGTATATATAGAAATCAAGAGATTTGGTGTTCGTGGTAA

Upstream 100 bases:

>100_bases
ACGTTTATAAATATGGGGAGGTTATAGGTAAAGCTATTAAATCTATAGAAATTGGCCAGTGTGTTCATATAGATAATATA
GAGAGCGTGAGGGGTAAGAG

Downstream 100 bases:

>100_bases
GGTAATAAAACATTCCTTAGATTATAAGAAGCTGAGAGTAAAAAAGGTTCAACACAAGTAAGACATTAAAATGAGGAGGG
GAGAAATAAAGATGAAGATT

Product: Altronate dehydratase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKIKAYKRPDGKYGIRNKVLILPSVGCANETARLISEQVQGTTYITNPKGCGQIGSSVELMHRTLIGLTLNPNVYGTIIV
GLGCETIQAYDLYEEVKKRSNKPVEVISIQREGGTLKTIQKGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSG
IAANPTLGYCSDILIKEGATVFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRLGIDVRGANPSPGNIKGG
LSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGYDIESVTGMVAGGAQICVFTTGRGTPIGNPIIPLIKIT
GNKQTYENMSDNIDLDVSDIIEGKKDIKECGEMLLQEIIDVCNGKLTKAEIYGFSETCIYRNQEIWCSW

Sequences:

>Translated_389_residues
MKIKAYKRPDGKYGIRNKVLILPSVGCANETARLISEQVQGTTYITNPKGCGQIGSSVELMHRTLIGLTLNPNVYGTIIV
GLGCETIQAYDLYEEVKKRSNKPVEVISIQREGGTLKTIQKGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSG
IAANPTLGYCSDILIKEGATVFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRLGIDVRGANPSPGNIKGG
LSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGYDIESVTGMVAGGAQICVFTTGRGTPIGNPIIPLIKIT
GNKQTYENMSDNIDLDVSDIIEGKKDIKECGEMLLQEIIDVCNGKLTKAEIYGFSETCIYRNQEIWCSW
>Mature_389_residues
MKIKAYKRPDGKYGIRNKVLILPSVGCANETARLISEQVQGTTYITNPKGCGQIGSSVELMHRTLIGLTLNPNVYGTIIV
GLGCETIQAYDLYEEVKKRSNKPVEVISIQREGGTLKTIQKGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSG
IAANPTLGYCSDILIKEGATVFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRLGIDVRGANPSPGNIKGG
LSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGYDIESVTGMVAGGAQICVFTTGRGTPIGNPIIPLIKIT
GNKQTYENMSDNIDLDVSDIIEGKKDIKECGEMLLQEIIDVCNGKLTKAEIYGFSETCIYRNQEIWCSW

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=392, Percent_Identity=33.4183673469388, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1789516, Length=382, Percent_Identity=36.3874345549738, Blast_Score=215, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 42402; Mature: 42402

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKAYKRPDGKYGIRNKVLILPSVGCANETARLISEQVQGTTYITNPKGCGQIGSSVEL
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHH
MHRTLIGLTLNPNVYGTIIVGLGCETIQAYDLYEEVKKRSNKPVEVISIQREGGTLKTIQ
HHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
KGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSGIAANPTLGYCSDILIKEGAT
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
VFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRLGIDVRGANPSPGNIKGG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCCC
LSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGYDIESVTGMVAGGAQICV
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHEECCCCEEEE
FTTGRGTPIGNPIIPLIKITGNKQTYENMSDNIDLDVSDIIEGKKDIKECGEMLLQEIID
EECCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
VCNGKLTKAEIYGFSETCIYRNQEIWCSW
HHCCCEEEEEEECCCHHEEEECCEEEECC
>Mature Secondary Structure
MKIKAYKRPDGKYGIRNKVLILPSVGCANETARLISEQVQGTTYITNPKGCGQIGSSVEL
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHH
MHRTLIGLTLNPNVYGTIIVGLGCETIQAYDLYEEVKKRSNKPVEVISIQREGGTLKTIQ
HHHHHEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHH
KGIKLARKMVEEMSKIEREEVDISNITLATNCGGSDATSGIAANPTLGYCSDILIKEGAT
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCE
VFLGETTEFIGAEHILARRAKNEKVRNNLLTIVKNLENEFIRLGIDVRGANPSPGNIKGG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCCCCCCC
LSTLEEKSLGSIMKGGTSIINEVVRYGEIPKEKGLIIMDTPGYDIESVTGMVAGGAQICV
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHEECCCCEEEE
FTTGRGTPIGNPIIPLIKITGNKQTYENMSDNIDLDVSDIIEGKKDIKECGEMLLQEIID
EECCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
VCNGKLTKAEIYGFSETCIYRNQEIWCSW
HHCCCEEEEEEECCCHHEEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]