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The map label for this gene is rho [H]

Identifier: 167038762

GI number: 167038762

Start: 88046

End: 89572

Strand: Direct

Name: rho [H]

Synonym: Teth514_0089

Alternate gene names: 167038762

Gene position: 88046-89572 (Clockwise)

Preceding gene: 167038761

Following gene: 167038763

Centisome position: 3.58

GC content: 35.17

Gene sequence:

>1527_bases
TTGCATTTTGATATTAATACTTTGGGAAATTTGAGTTTGATGGAACTGAGAGAAATTGCAAAAGAGTTAGGCATTAAAAG
TATTACGAAATACAGAAAACAAGAGCTGAGAGAAAAAATTTTGGAAAAAGTTAGTCAATTAAATGGAGAAAATTTAATTC
AAGAGGATAACAGAAAAGAGGAAGGTTTAAATGAGGGGCCAACACAAGAATTACAAGAAAGTAGGGTAGGGAAAAATACA
GACGATACTTCAAATACAAATTCTAACATATCGAAAAATGGATATGCAAAGTCTATTAGTACTGAAAATAGCGCAAATGG
ATTACAAGCTCAATCAAAGCCTTCAAAAGACATCTTGCCAATTGCTAAAGAACTTTCTGATCCATTGAAAGAACTTATAC
AGACACAAGGAGATGTAGTGGCAGAAGGCATTCTTGATATTTTGCCAGATGGTTACGGATTTTTAAGAGTAGAAAACTTT
GTTCAAGGGCCTAAAGATATATATATTTCTCAATCGCAAATAAGGCGTTTTGGCTTAAAAGTTGGCGACAAAGTAAGAGG
TATTACAAGGATTCCTAGAGAAGGGGAAAAATATTCTGCAATTCTTTATGTGGAATCTATAAATGGTGAAGATCCCGAAA
ATGCTAAAAAAAGGATTCCCTTTGATGAATTAACTCCTATTTTCCCAAATGAGAAATTGAGATTAGAGACTTCACCTACA
GAATTTTCCATGAGATTGGTAGATATCATTGCTCCTATAGGTAAAGGGCAAAGGGGTATGATTGTTGCACCGCCAAAAGC
AGGAAAAACCACTTTACTTAAGCAAATTGCCAATAGCATTTCACAAAACCATCCAGAAGTTATTCTCATTGTGCTTTTAA
TTGATGAACGCCCTGAAGAAGTAACTGACATGAAACGTTCTATAAAAGGAGAAGTAGTATATTCTACTTTTGATGAACTC
CCAGAACACCATACTAAAGTGGCTGAAATGGTATTAGAGCACGCTAAAAGACTTGTGGAGTATAAAAAGGATGTGGTGAT
TCTTTTAGATAGTATTACTAGGTTAGCGAGAGCTTATAACCTTATTACACCTCCTTCAGGAAGAACTCTTTCTGGTGGCA
TTGACCCTTCTGCATTACATCCTCCGAAAAGATTTTTTGGAGCAGCCAGGAATATAGAAGAGGGTGGAAGTTTAACTATC
CTTGCTACTGCTTTGATTGAAACGGGAAGCCGCATGGATGAAGTTATATTTGAAGAATTTAAGGGAACGGGCAATATGGA
ACTTCACCTTGACAGAAAATTACAAGAAAGAAGGATATTCCCTGCTATTGATATATACAAATCGGGTACAAGAAAAGAAG
AATTGCTGCTTACTAAAGAAGAATTGGAGGCCATGTGGATATTAAGGAAAGCCATGTCAAATTTACCGCCTGCAGAGGTT
ACAGAGATGTTAATTGAAAAATTAATACGAACTAAATCTAATGCGGAGTTTATAAATATGATAAGAGCACAATTATATAA
ATCTTGA

Upstream 100 bases:

>100_bases
TCTCATTTTTATCCTCCAGGTAAGTTCCCTCTTATACTTTTTTAAAAATGAGGTAATGAGGACTTAGTTTGTTAAAATTC
TACTTTTGGGAGGTGTACAT

Downstream 100 bases:

>100_bases
TATTGTGTATAACTTGTGTTATAATTTCTCCGTATGAGTTTTGGTTGAAAGAGGTGAAAGCTGTGAAACCGAATATACAT
CCTACCTATTATCATGATGC

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MHFDINTLGNLSLMELREIAKELGIKSITKYRKQELREKILEKVSQLNGENLIQEDNRKEEGLNEGPTQELQESRVGKNT
DDTSNTNSNISKNGYAKSISTENSANGLQAQSKPSKDILPIAKELSDPLKELIQTQGDVVAEGILDILPDGYGFLRVENF
VQGPKDIYISQSQIRRFGLKVGDKVRGITRIPREGEKYSAILYVESINGEDPENAKKRIPFDELTPIFPNEKLRLETSPT
EFSMRLVDIIAPIGKGQRGMIVAPPKAGKTTLLKQIANSISQNHPEVILIVLLIDERPEEVTDMKRSIKGEVVYSTFDEL
PEHHTKVAEMVLEHAKRLVEYKKDVVILLDSITRLARAYNLITPPSGRTLSGGIDPSALHPPKRFFGAARNIEEGGSLTI
LATALIETGSRMDEVIFEEFKGTGNMELHLDRKLQERRIFPAIDIYKSGTRKEELLLTKEELEAMWILRKAMSNLPPAEV
TEMLIEKLIRTKSNAEFINMIRAQLYKS

Sequences:

>Translated_508_residues
MHFDINTLGNLSLMELREIAKELGIKSITKYRKQELREKILEKVSQLNGENLIQEDNRKEEGLNEGPTQELQESRVGKNT
DDTSNTNSNISKNGYAKSISTENSANGLQAQSKPSKDILPIAKELSDPLKELIQTQGDVVAEGILDILPDGYGFLRVENF
VQGPKDIYISQSQIRRFGLKVGDKVRGITRIPREGEKYSAILYVESINGEDPENAKKRIPFDELTPIFPNEKLRLETSPT
EFSMRLVDIIAPIGKGQRGMIVAPPKAGKTTLLKQIANSISQNHPEVILIVLLIDERPEEVTDMKRSIKGEVVYSTFDEL
PEHHTKVAEMVLEHAKRLVEYKKDVVILLDSITRLARAYNLITPPSGRTLSGGIDPSALHPPKRFFGAARNIEEGGSLTI
LATALIETGSRMDEVIFEEFKGTGNMELHLDRKLQERRIFPAIDIYKSGTRKEELLLTKEELEAMWILRKAMSNLPPAEV
TEMLIEKLIRTKSNAEFINMIRAQLYKS
>Mature_508_residues
MHFDINTLGNLSLMELREIAKELGIKSITKYRKQELREKILEKVSQLNGENLIQEDNRKEEGLNEGPTQELQESRVGKNT
DDTSNTNSNISKNGYAKSISTENSANGLQAQSKPSKDILPIAKELSDPLKELIQTQGDVVAEGILDILPDGYGFLRVENF
VQGPKDIYISQSQIRRFGLKVGDKVRGITRIPREGEKYSAILYVESINGEDPENAKKRIPFDELTPIFPNEKLRLETSPT
EFSMRLVDIIAPIGKGQRGMIVAPPKAGKTTLLKQIANSISQNHPEVILIVLLIDERPEEVTDMKRSIKGEVVYSTFDEL
PEHHTKVAEMVLEHAKRLVEYKKDVVILLDSITRLARAYNLITPPSGRTLSGGIDPSALHPPKRFFGAARNIEEGGSLTI
LATALIETGSRMDEVIFEEFKGTGNMELHLDRKLQERRIFPAIDIYKSGTRKEELLLTKEELEAMWILRKAMSNLPPAEV
TEMLIEKLIRTKSNAEFINMIRAQLYKS

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=379, Percent_Identity=60.4221635883905, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 57196; Mature: 57196

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFDINTLGNLSLMELREIAKELGIKSITKYRKQELREKILEKVSQLNGENLIQEDNRKE
CCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHH
EGLNEGPTQELQESRVGKNTDDTSNTNSNISKNGYAKSISTENSANGLQAQSKPSKDILP
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
IAKELSDPLKELIQTQGDVVAEGILDILPDGYGFLRVENFVQGPKDIYISQSQIRRFGLK
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEHHHHCCCHHEEECHHHHHHHHCH
VGDKVRGITRIPREGEKYSAILYVESINGEDPENAKKRIPFDELTPIFPNEKLRLETSPT
HCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCHHHHCCCHHHCCCCCCCCCEEEECCCH
EFSMRLVDIIAPIGKGQRGMIVAPPKAGKTTLLKQIANSISQNHPEVILIVLLIDERPEE
HHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
VTDMKRSIKGEVVYSTFDELPEHHTKVAEMVLEHAKRLVEYKKDVVILLDSITRLARAYN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LITPPSGRTLSGGIDPSALHPPKRFFGAARNIEEGGSLTILATALIETGSRMDEVIFEEF
CCCCCCCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHCCCHHHHHHHHHH
KGTGNMELHLDRKLQERRIFPAIDIYKSGTRKEELLLTKEELEAMWILRKAMSNLPPAEV
CCCCCEEEEECHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TEMLIEKLIRTKSNAEFINMIRAQLYKS
HHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MHFDINTLGNLSLMELREIAKELGIKSITKYRKQELREKILEKVSQLNGENLIQEDNRKE
CCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHH
EGLNEGPTQELQESRVGKNTDDTSNTNSNISKNGYAKSISTENSANGLQAQSKPSKDILP
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
IAKELSDPLKELIQTQGDVVAEGILDILPDGYGFLRVENFVQGPKDIYISQSQIRRFGLK
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEHHHHCCCHHEEECHHHHHHHHCH
VGDKVRGITRIPREGEKYSAILYVESINGEDPENAKKRIPFDELTPIFPNEKLRLETSPT
HCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCHHHHCCCHHHCCCCCCCCCEEEECCCH
EFSMRLVDIIAPIGKGQRGMIVAPPKAGKTTLLKQIANSISQNHPEVILIVLLIDERPEE
HHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
VTDMKRSIKGEVVYSTFDELPEHHTKVAEMVLEHAKRLVEYKKDVVILLDSITRLARAYN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LITPPSGRTLSGGIDPSALHPPKRFFGAARNIEEGGSLTILATALIETGSRMDEVIFEEF
CCCCCCCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHCCCHHHHHHHHHH
KGTGNMELHLDRKLQERRIFPAIDIYKSGTRKEELLLTKEELEAMWILRKAMSNLPPAEV
CCCCCEEEEECHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TEMLIEKLIRTKSNAEFINMIRAQLYKS
HHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]