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The map label for this gene is fba [H]

Identifier: 167038761

GI number: 167038761

Start: 86888

End: 87739

Strand: Direct

Name: fba [H]

Synonym: Teth514_0088

Alternate gene names: 167038761

Gene position: 86888-87739 (Clockwise)

Preceding gene: 167038760

Following gene: 167038762

Centisome position: 3.54

GC content: 37.91

Gene sequence:

>852_bases
ATGTTAGTGACAGGTATAGAGATATTGGAAAAGGCCCATAAAGAAGGATATGCAGTTGGAGCTTTTAACACCAGTAATTT
AGAAATTACTCAAGCCATTGTGGAAGCAGCAGAAGAGACTAAATCACCAGTCATAATACAAGTCAGTGAGGGAGGATTGA
AATACGCTGGTATTGAGACGATTTCAGCGATTGTCAGGACAATGGCGGAAAAAGCGTCAGTTCCAATTGCCCTTCACCTT
GACCATGGTACAGATTTCAATACGGTCATGAAATGCTTGAGAAATGGTTGGACTTCTGTAATGATGGATGCATCAAAATT
GCCACTCGAAGAAAATATAAAAGTGACGAAAACTGTGGTGCAAATTGCTCACGGAATGGGAGTTTCTGTTGAAGCTGAAA
TCGGAAAAATTGGTGGTACAGAGGATAATATCACAGTAGATGAAAGAGAAGCGGCTATGACAGACCCAGAAGAAGCTTTA
AAATTCGCAAAAGAAACAGGAGTAGATTATTTAGCTATAGCTATTGGGACAGCTCATGGACCTTACAAAGGAGAACCTAA
GCTGGACTTTGATAGACTTAAAAAAATAAAAGAAATGCTCAATATTCCTTTAGTTTTACATGGAGCTTCAGGAGTTCCTG
AAGAGGCTATAAAGAAGGCTGTAAGCCTTGGCATAAATAAGATAAACATAGATACGGATATAAGACAAGCTTTTGCACGA
AGACTAAGAGATTTATTAGAAAAAGATAGTGAAGTATACGACCCAAGAAAAATTTTAGGTCCGTGTAAAGATGCGATGAA
AGAAGTAATTAAGCAAAAAATGATTTTATTTGGAGCAGCAGGAAGAGCATAA

Upstream 100 bases:

>100_bases
TTTCTTGAGCTAGCTTTAAACAAATGCTATAATGAAAAAGTAAAGTTACATAATATTAGGTAGTATTTTGAAAACAGTTA
TAATAAAGGAGTTGTTAGAA

Downstream 100 bases:

>100_bases
TTTAAAGCGGGGTTTCACCGCTTTTTATTTTTTATGTATAAATTTTTACAAATTGTCAATTATAAATTTGGGACTGAAAA
TAACTACTTGACATTCCAAA

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLVTGIEILEKAHKEGYAVGAFNTSNLEITQAIVEAAEETKSPVIIQVSEGGLKYAGIETISAIVRTMAEKASVPIALHL
DHGTDFNTVMKCLRNGWTSVMMDASKLPLEENIKVTKTVVQIAHGMGVSVEAEIGKIGGTEDNITVDEREAAMTDPEEAL
KFAKETGVDYLAIAIGTAHGPYKGEPKLDFDRLKKIKEMLNIPLVLHGASGVPEEAIKKAVSLGINKINIDTDIRQAFAR
RLRDLLEKDSEVYDPRKILGPCKDAMKEVIKQKMILFGAAGRA

Sequences:

>Translated_283_residues
MLVTGIEILEKAHKEGYAVGAFNTSNLEITQAIVEAAEETKSPVIIQVSEGGLKYAGIETISAIVRTMAEKASVPIALHL
DHGTDFNTVMKCLRNGWTSVMMDASKLPLEENIKVTKTVVQIAHGMGVSVEAEIGKIGGTEDNITVDEREAAMTDPEEAL
KFAKETGVDYLAIAIGTAHGPYKGEPKLDFDRLKKIKEMLNIPLVLHGASGVPEEAIKKAVSLGINKINIDTDIRQAFAR
RLRDLLEKDSEVYDPRKILGPCKDAMKEVIKQKMILFGAAGRA
>Mature_283_residues
MLVTGIEILEKAHKEGYAVGAFNTSNLEITQAIVEAAEETKSPVIIQVSEGGLKYAGIETISAIVRTMAEKASVPIALHL
DHGTDFNTVMKCLRNGWTSVMMDASKLPLEENIKVTKTVVQIAHGMGVSVEAEIGKIGGTEDNITVDEREAAMTDPEEAL
KFAKETGVDYLAIAIGTAHGPYKGEPKLDFDRLKKIKEMLNIPLVLHGASGVPEEAIKKAVSLGINKINIDTDIRQAFAR
RLRDLLEKDSEVYDPRKILGPCKDAMKEVIKQKMILFGAAGRA

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=282, Percent_Identity=45.0354609929078, Blast_Score=261, Evalue=3e-71,
Organism=Escherichia coli, GI1789526, Length=275, Percent_Identity=42.9090909090909, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI1788072, Length=275, Percent_Identity=40.3636363636364, Blast_Score=200, Evalue=7e-53,
Organism=Escherichia coli, GI1789293, Length=279, Percent_Identity=28.3154121863799, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322790, Length=290, Percent_Identity=27.5862068965517, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30738; Mature: 30738

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVTGIEILEKAHKEGYAVGAFNTSNLEITQAIVEAAEETKSPVIIQVSEGGLKYAGIET
CEECHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHH
ISAIVRTMAEKASVPIALHLDHGTDFNTVMKCLRNGWTSVMMDASKLPLEENIKVTKTVV
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCHHHCCCCCCCHHHHHHH
QIAHGMGVSVEAEIGKIGGTEDNITVDEREAAMTDPEEALKFAKETGVDYLAIAIGTAHG
HHHHCCCCEEEEHHCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCC
PYKGEPKLDFDRLKKIKEMLNIPLVLHGASGVPEEAIKKAVSLGINKINIDTDIRQAFAR
CCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHH
RLRDLLEKDSEVYDPRKILGPCKDAMKEVIKQKMILFGAAGRA
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLVTGIEILEKAHKEGYAVGAFNTSNLEITQAIVEAAEETKSPVIIQVSEGGLKYAGIET
CEECHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHH
ISAIVRTMAEKASVPIALHLDHGTDFNTVMKCLRNGWTSVMMDASKLPLEENIKVTKTVV
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCHHHHHCHHHCCCCCCCHHHHHHH
QIAHGMGVSVEAEIGKIGGTEDNITVDEREAAMTDPEEALKFAKETGVDYLAIAIGTAHG
HHHHCCCCEEEEHHCCCCCCCCCCEECCHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCC
PYKGEPKLDFDRLKKIKEMLNIPLVLHGASGVPEEAIKKAVSLGINKINIDTDIRQAFAR
CCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHH
RLRDLLEKDSEVYDPRKILGPCKDAMKEVIKQKMILFGAAGRA
HHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA