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The map label for this gene is ribD [H]

Identifier: 167038695

GI number: 167038695

Start: 24174

End: 25256

Strand: Direct

Name: ribD [H]

Synonym: Teth514_0020

Alternate gene names: 167038695

Gene position: 24174-25256 (Clockwise)

Preceding gene: 167038694

Following gene: 167038696

Centisome position: 0.98

GC content: 34.44

Gene sequence:

>1083_bases
TTGGAAGAATATATGAAAAGGGCTTTAACGCTGGCTAAAAAAGGATGGGGATACACAAACCCTAATCCACTTGTGGGTGC
TGTAATAGTTAAAAATGGAAAAATAATAGGTGAGGGTTATCATGAATATTTTGGAGGGCCACATGCTGAAGTAAATGCAT
TAAAAAATGCAGTTGAAAATGTTGAAGGTTCTACTATGTTTGTAACACTTGAACCTTGCAGCCATTATGGCAAAACGCCT
CCTTGTGTTGAAGAAATAATTAAATCTGGCATTAAGAGAGTGTATATAGCGATGGAAGACCCAAATCCTAAGGTTAGCGG
GAACGGTATAAAAAGGTTAAAAGAGGCGGGAATAGAAGTACATGTGGGGATGATGGAGAAAGAAGCGAGGAAACTCAACG
AAATATTTGTTAAATATATTACGACAAAATTCCCCTTTGTGATATTAAAATCTGCTATGAGTATTGATGGTAAGATTGCT
TGTTATAATGGAAATTCTAAATGGATTACAAATGAGAAATCAAGAAAATTTGCTCATAAAATAAGAGGACGGGTATCCGC
CATTATGGTTGGGGTAAATACAGTAATTAAGGATAACCCAATGCTTACAACAAGGTTGGAGGGGTATAAAAATCCTGTAA
GGATTATTGTGGATAGTAGAGGTAGAATTCCACTTGACTCAAATGTAATAAGAGACAAAACGGCAAAAACGATAATTGCT
ACAACAGAACTTATGCCAAACAATGTGAGAAAGAAGCTTGAAGATATGGATATTGAAGTTATTATATTAAAGAACGACAA
TGGAAAAGTACCTTTAAAAGAGCTAATGATAAAACTTGGAGAGAGGGGGATTGATAGTGTATTGATTGAAGGCGGTGGGA
CATTAAATTGGTCTGCACTTAAAGAGGGAATTGTTGATAAAGTTATGTTTTTTATATCACCTAGAATAATAGGAGGAAAA
AATGCTTTAACACCTGTAGAAGGTATAGGTTTTTCGGATATAGGAAATTCAATAGAATTAAAAGATGTGGAGATTGATAG
AATAGATGATGATATACTAATAACAGCATATGTAAGAAAGTAG

Upstream 100 bases:

>100_bases
TGGGAGAAGGAGAAATATTCCCCAGGGAATATGTTCTCTGGGGGTTTTTTTAACCCTGGAGGTTTAACCTTCAGGATTTT
TTAGTATAGGAGGGATTAAA

Downstream 100 bases:

>100_bases
GTTATGGCGTATGTTTACTGGAATTATAGAAGAAACAGGAACTGTTAAGAATATTACACATGGTACTTTTACAAAAATTG
TTATAAAATGTAGCAAAGTC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MEEYMKRALTLAKKGWGYTNPNPLVGAVIVKNGKIIGEGYHEYFGGPHAEVNALKNAVENVEGSTMFVTLEPCSHYGKTP
PCVEEIIKSGIKRVYIAMEDPNPKVSGNGIKRLKEAGIEVHVGMMEKEARKLNEIFVKYITTKFPFVILKSAMSIDGKIA
CYNGNSKWITNEKSRKFAHKIRGRVSAIMVGVNTVIKDNPMLTTRLEGYKNPVRIIVDSRGRIPLDSNVIRDKTAKTIIA
TTELMPNNVRKKLEDMDIEVIILKNDNGKVPLKELMIKLGERGIDSVLIEGGGTLNWSALKEGIVDKVMFFISPRIIGGK
NALTPVEGIGFSDIGNSIELKDVEIDRIDDDILITAYVRK

Sequences:

>Translated_360_residues
MEEYMKRALTLAKKGWGYTNPNPLVGAVIVKNGKIIGEGYHEYFGGPHAEVNALKNAVENVEGSTMFVTLEPCSHYGKTP
PCVEEIIKSGIKRVYIAMEDPNPKVSGNGIKRLKEAGIEVHVGMMEKEARKLNEIFVKYITTKFPFVILKSAMSIDGKIA
CYNGNSKWITNEKSRKFAHKIRGRVSAIMVGVNTVIKDNPMLTTRLEGYKNPVRIIVDSRGRIPLDSNVIRDKTAKTIIA
TTELMPNNVRKKLEDMDIEVIILKNDNGKVPLKELMIKLGERGIDSVLIEGGGTLNWSALKEGIVDKVMFFISPRIIGGK
NALTPVEGIGFSDIGNSIELKDVEIDRIDDDILITAYVRK
>Mature_360_residues
MEEYMKRALTLAKKGWGYTNPNPLVGAVIVKNGKIIGEGYHEYFGGPHAEVNALKNAVENVEGSTMFVTLEPCSHYGKTP
PCVEEIIKSGIKRVYIAMEDPNPKVSGNGIKRLKEAGIEVHVGMMEKEARKLNEIFVKYITTKFPFVILKSAMSIDGKIA
CYNGNSKWITNEKSRKFAHKIRGRVSAIMVGVNTVIKDNPMLTTRLEGYKNPVRIIVDSRGRIPLDSNVIRDKTAKTIIA
TTELMPNNVRKKLEDMDIEVIILKNDNGKVPLKELMIKLGERGIDSVLIEGGGTLNWSALKEGIVDKVMFFISPRIIGGK
NALTPVEGIGFSDIGNSIELKDVEIDRIDDDILITAYVRK

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=366, Percent_Identity=37.7049180327869, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39973; Mature: 39973

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEYMKRALTLAKKGWGYTNPNPLVGAVIVKNGKIIGEGYHEYFGGPHAEVNALKNAVEN
CHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEECCHHHHCCCCCHHHHHHHHHHHC
VEGSTMFVTLEPCSHYGKTPPCVEEIIKSGIKRVYIAMEDPNPKVSGNGIKRLKEAGIEV
CCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEE
HVGMMEKEARKLNEIFVKYITTKFPFVILKSAMSIDGKIACYNGNSKWITNEKSRKFAHK
EEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHH
IRGRVSAIMVGVNTVIKDNPMLTTRLEGYKNPVRIIVDSRGRIPLDSNVIRDKTAKTIIA
HHHHHEEEEEEHHHEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCHHCCHHCEEEE
TTELMPNNVRKKLEDMDIEVIILKNDNGKVPLKELMIKLGERGIDSVLIEGGGTLNWSAL
EHHHCCHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCEEEHHHH
KEGIVDKVMFFISPRIIGGKNALTPVEGIGFSDIGNSIELKDVEIDRIDDDILITAYVRK
HHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure
MEEYMKRALTLAKKGWGYTNPNPLVGAVIVKNGKIIGEGYHEYFGGPHAEVNALKNAVEN
CHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEECCHHHHCCCCCHHHHHHHHHHHC
VEGSTMFVTLEPCSHYGKTPPCVEEIIKSGIKRVYIAMEDPNPKVSGNGIKRLKEAGIEV
CCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEE
HVGMMEKEARKLNEIFVKYITTKFPFVILKSAMSIDGKIACYNGNSKWITNEKSRKFAHK
EEEHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHH
IRGRVSAIMVGVNTVIKDNPMLTTRLEGYKNPVRIIVDSRGRIPLDSNVIRDKTAKTIIA
HHHHHEEEEEEHHHEECCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCHHCCHHCEEEE
TTELMPNNVRKKLEDMDIEVIILKNDNGKVPLKELMIKLGERGIDSVLIEGGGTLNWSAL
EHHHCCHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCEEEHHHH
KEGIVDKVMFFISPRIIGGKNALTPVEGIGFSDIGNSIELKDVEIDRIDDDILITAYVRK
HHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]