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The map label for this gene is dnaA

Identifier: 167038676

GI number: 167038676

Start: 195

End: 1526

Strand: Direct

Name: dnaA

Synonym: Teth514_0001

Alternate gene names: 167038676

Gene position: 195-1526 (Clockwise)

Preceding gene: NA

Following gene: 167038677

Centisome position: 0.01

GC content: 33.18

Gene sequence:

>1332_bases
ATGTATGGAGATCATCGTCAAATATGGGAGAGGATAGTGGAGGTCATAAAAAGCGAGCTTACCCCCACCAGCTACAACAC
CTGGCTAGTTCACATAAAACCCTTAGCAATTATTGATGATGTGTTATTTTTAAGCACTCCTAATACTTTTACAAAAAATA
TAATAAATGGAAGATATATAAATATTATCTACGACGCTGCTTCAAAAGCTACAAATAAATTATACGAGATAAAAATATTA
TCAGAAGACGAAGAAGAATATAGAGAAATCAAAGAATCTATTGAAAAAGAAAACCTAACTGAATCCACTACTCTTTCCAC
TCTAAATCCAAAATATACTTTTGATACTTTTGTAGTTGGAAACAGCAATAAACTTGCTCACGCTGCATGTCTTGCAGTAG
CTCAGGCTCCAGCAAAAGCCTATAATCCTTTATTTATCTATGGAGGAGTAGGTTTAGGCAAAACCCATTTAATGCATGCA
ATAGGGCACTTTATCAATAAACATCAAAGTGGCTACAAAATAATGTACGTTACGTCAGAAACGTTTACAAACGAGTTAGT
TAACTCCATAAAAGACGACAAAAATGAAGAATTTAGAAACAAGTACAGAAATATTGATGTTCTTCTAATAGATGATATTC
AATTTATAGCCAAAAAAGAACGAACTCAAGAAGAATTTTTCCATACTTTTAACACCCTTTACGAAGCCAACAAGCAAATA
GTTATTTCCAGTGACAGACCACCAAAAGAAATTCCAACTTTAGAAGAAAGGCTAAGGTCAAGGTTTGAGTGGGGTTTAAT
CGCGGATATACAGCCACCAGATTATGAGACAAGAATTGCAATACTTAAGAAAAAGGCTCAAACAGAAAATCTAAATATAC
CCGACGAAGTTTTAGCTTATGTGGCAGAAAAAATTCAATCAAATATAAGAGAGTTAGAAGGAGCATTAATAAGAATCGTA
GCTTTTTCAAATCTTACAAAAGCCAATATAGACTTAGAATTAGCTAAGCATGCCTTAAAGGAAATTGTATCTAATAAAAC
GAGAGAAATAACTGTAAAACTCATACAGGAAGAAGTTTGCAAGTACTATAACATAAAACTAGAAGATTTCAGGTCCCGCA
AGAGAACAAAAAACATAGCTTATCCGCGACAAATCGCCATGTACTTAGCAAGAGAACTGACAGATTTATCTCTTCCAAAA
ATAGGAGAAGAATTTGGAAAAGACCATACTACTGTAATACATGCTTATGAAAAAATTTCTAATGAAATAAAACAAGATGA
ACTTCTCTCAAGGCAGATTGAGGAACTTAAAAAGAGGATAAAAGGTTATTGA

Upstream 100 bases:

>100_bases
AAATTTAACTTATTAACAACTAAATTATACCGATAATATATTATGCCACCCTTTTAAATAAATTATCCACATTTTATTGA
TGGGCTTAGGAGGTCATATA

Downstream 100 bases:

>100_bases
CATATAAACAGGGATAACCCTGTTTATATGTTTTAAAATTTTTTGTCTGTGAATATTGTTAATAAATTTAACTGTTTACT
CAGAAATTATTCACAGACAA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MYGDHRQIWERIVEVIKSELTPTSYNTWLVHIKPLAIIDDVLFLSTPNTFTKNIINGRYINIIYDAASKATNKLYEIKIL
SEDEEEYREIKESIEKENLTESTTLSTLNPKYTFDTFVVGNSNKLAHAACLAVAQAPAKAYNPLFIYGGVGLGKTHLMHA
IGHFINKHQSGYKIMYVTSETFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIAKKERTQEEFFHTFNTLYEANKQI
VISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRIAILKKKAQTENLNIPDEVLAYVAEKIQSNIRELEGALIRIV
AFSNLTKANIDLELAKHALKEIVSNKTREITVKLIQEEVCKYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPK
IGEEFGKDHTTVIHAYEKISNEIKQDELLSRQIEELKKRIKGY

Sequences:

>Translated_443_residues
MYGDHRQIWERIVEVIKSELTPTSYNTWLVHIKPLAIIDDVLFLSTPNTFTKNIINGRYINIIYDAASKATNKLYEIKIL
SEDEEEYREIKESIEKENLTESTTLSTLNPKYTFDTFVVGNSNKLAHAACLAVAQAPAKAYNPLFIYGGVGLGKTHLMHA
IGHFINKHQSGYKIMYVTSETFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIAKKERTQEEFFHTFNTLYEANKQI
VISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRIAILKKKAQTENLNIPDEVLAYVAEKIQSNIRELEGALIRIV
AFSNLTKANIDLELAKHALKEIVSNKTREITVKLIQEEVCKYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPK
IGEEFGKDHTTVIHAYEKISNEIKQDELLSRQIEELKKRIKGY
>Mature_443_residues
MYGDHRQIWERIVEVIKSELTPTSYNTWLVHIKPLAIIDDVLFLSTPNTFTKNIINGRYINIIYDAASKATNKLYEIKIL
SEDEEEYREIKESIEKENLTESTTLSTLNPKYTFDTFVVGNSNKLAHAACLAVAQAPAKAYNPLFIYGGVGLGKTHLMHA
IGHFINKHQSGYKIMYVTSETFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIAKKERTQEEFFHTFNTLYEANKQI
VISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRIAILKKKAQTENLNIPDEVLAYVAEKIQSNIRELEGALIRIV
AFSNLTKANIDLELAKHALKEIVSNKTREITVKLIQEEVCKYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPK
IGEEFGKDHTTVIHAYEKISNEIKQDELLSRQIEELKKRIKGY

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=456, Percent_Identity=41.2280701754386, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI226510964, Length=222, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_THEP3 (B0KAG0)

Other databases:

- EMBL:   CP000924
- RefSeq:   YP_001664010.1
- ProteinModelPortal:   B0KAG0
- GeneID:   5873697
- GenomeReviews:   CP000924_GR
- KEGG:   tpd:Teth39_0001
- HOGENOM:   HBG695666
- OMA:   CHTLNAL
- ProtClustDB:   PRK00149
- BioCyc:   TPSE340099:TETH39_0001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 51385; Mature: 51385

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGDHRQIWERIVEVIKSELTPTSYNTWLVHIKPLAIIDDVLFLSTPNTFTKNIINGRYI
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHCCCCCHHHHHCCCCEEE
NIIYDAASKATNKLYEIKILSEDEEEYREIKESIEKENLTESTTLSTLNPKYTFDTFVVG
EEEEECHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEC
NSNKLAHAACLAVAQAPAKAYNPLFIYGGVGLGKTHLMHAIGHFINKHQSGYKIMYVTSE
CCCCHHHHHHHHHHHCCHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECH
TFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIAKKERTQEEFFHTFNTLYEANKQI
HHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRIAILKKKAQTENLNIPDEVLAY
EEECCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
VAEKIQSNIRELEGALIRIVAFSNLTKANIDLELAKHALKEIVSNKTREITVKLIQEEVC
HHHHHHHHHHHHHHHHEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPKIGEEFGKDHTTVIHAYEKIS
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHH
NEIKQDELLSRQIEELKKRIKGY
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYGDHRQIWERIVEVIKSELTPTSYNTWLVHIKPLAIIDDVLFLSTPNTFTKNIINGRYI
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHHHHHCCCCCHHHHHCCCCEEE
NIIYDAASKATNKLYEIKILSEDEEEYREIKESIEKENLTESTTLSTLNPKYTFDTFVVG
EEEEECHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEEEEEC
NSNKLAHAACLAVAQAPAKAYNPLFIYGGVGLGKTHLMHAIGHFINKHQSGYKIMYVTSE
CCCCHHHHHHHHHHHCCHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECH
TFTNELVNSIKDDKNEEFRNKYRNIDVLLIDDIQFIAKKERTQEEFFHTFNTLYEANKQI
HHHHHHHHHHCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VISSDRPPKEIPTLEERLRSRFEWGLIADIQPPDYETRIAILKKKAQTENLNIPDEVLAY
EEECCCCCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHH
VAEKIQSNIRELEGALIRIVAFSNLTKANIDLELAKHALKEIVSNKTREITVKLIQEEVC
HHHHHHHHHHHHHHHHEEEHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KYYNIKLEDFRSRKRTKNIAYPRQIAMYLARELTDLSLPKIGEEFGKDHTTVIHAYEKIS
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHH
NEIKQDELLSRQIEELKKRIKGY
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA