Click here to switch to the map view.

The map label for this gene is obgE

Identifier: 163845422

GI number: 163845422

Start: 1284435

End: 1285460

Strand: Reverse

Name: obgE

Synonym: BSUIS_B1323

Alternate gene names: 163845422

Gene position: 1285460-1284435 (Counterclockwise)

Preceding gene: 163845423

Following gene: 163845421

Centisome position: 91.76

GC content: 59.36

Gene sequence:

>1026_bases
ATGAAGTTTCTCGATCAGGCCAAGATCTATATCCGCTCCGGCAATGGCGGGGCAGGGGCCGTTTCGTTCCGCCGCGAGAA
ATTTCTTGAATTCGGCGGCCCGGATGGCGGTGACGGCGGACGCGGCGGCGATGTCTGGGTGGAGGCCGTGGACGGTCTCA
ACACGCTGATCGATTATCGCTATCAGCAGCATTTCAAGGCCAAGACCGGCATGCACGGCATGGGTCGCAACATGACAGGC
GGCAAGGGCGACGATGTGGTGCTGAGGGTGCCGGTCGGCACGCAGATTTTCGAGGAAGACAACGAAACGCTGATCTGCGA
CATCACCGAGGTGGGGCAGCGTTATCGTCTTGCCAAAGGGGGCAATGGCGGCTTTGGCAACCTGCATTTCACCACCTCCA
CCAATCGTGCGCCGCGCCGTGCCAATCCGGGGCAGGAAGGTATTGAGCGCACCATCTGGCTGCGCCTGAAGCTGATTGCC
GATGCGGGACTGGTGGGCTTGCCCAATGCGGGAAAATCCACTTTTCTGGCAAGCGTGACGGCTGCAAAACCAAAGATTGC
CGATTATCCCTTTACCACGCTGCACCCGAACCTTGGCGTTGCGCGTATTGATGGGCGCGAATTCGTTATTGCCGACATTC
CGGGCCTGATCGAAGGTGCAAGCGAAGGTGTGGGCCTTGGCGACCGTTTTCTCGGCCATGTCGAGCGTACGCGCGTTCTG
CTGCATCTGGTTTCTGCGCAGGAAGAGGATGTGGCGAAGGCCTATCAGGTTATTCGCGGCGAACTGGAAGCTTATGAGCA
CGGGCTTGCCGACAAGCCGGAAATCGTGGCGCTGTCGCAGGTCGATACGCTTGATCCTGAAACGCGCAAGGCCAAGGTCA
AGGCGCTGAAAAAGGCATGTGGGTGCGAGCCCCTGCTGCTTTCGGCCGTCAGCCATGAGGGTTTGAACGATACGCTGCGG
CAACTTGCGCGTATCATTGATCTGAGCCGCGCCGAAGAGGCTGGAACGGCGCAAGCCGAAGAGTAA

Upstream 100 bases:

>100_bases
GCAACGTCACATGCGGGCATTGCCCGCATGTGACGAGATTAAGAGTCCTTTCGGGCTCAAAAGCCGGCTGCGAAGCGGGC
ATCCAAGAAGGTTATGTTCA

Downstream 100 bases:

>100_bases
GGCTTCTGCGGCGAGAGGAATGAAACCATGCTGAAGAAACTAAAAGACTATCGCCGCATCGTTGTTAAAATAGGCTCTGC
CCTTCTGGTGGACCGGGCCA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYRYQQHFKAKTGMHGMGRNMTG
GKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIA
DAGLVGLPNAGKSTFLASVTAAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVL
LHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKACGCEPLLLSAVSHEGLNDTLR
QLARIIDLSRAEEAGTAQAEE

Sequences:

>Translated_341_residues
MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYRYQQHFKAKTGMHGMGRNMTG
GKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIA
DAGLVGLPNAGKSTFLASVTAAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVL
LHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKACGCEPLLLSAVSHEGLNDTLR
QLARIIDLSRAEEAGTAQAEE
>Mature_341_residues
MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYRYQQHFKAKTGMHGMGRNMTG
GKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKGGNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIA
DAGLVGLPNAGKSTFLASVTAAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVL
LHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKACGCEPLLLSAVSHEGLNDTLR
QLARIIDLSRAEEAGTAQAEE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=337, Percent_Identity=39.7626112759644, Blast_Score=185, Evalue=4e-47,
Organism=Homo sapiens, GI111955139, Length=299, Percent_Identity=37.123745819398, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI111955063, Length=133, Percent_Identity=41.3533834586466, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI58761500, Length=105, Percent_Identity=34.2857142857143, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4758796, Length=126, Percent_Identity=36.5079365079365, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI4557537, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789574, Length=350, Percent_Identity=49.1428571428571, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1787454, Length=108, Percent_Identity=39.8148148148148, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=318, Percent_Identity=36.7924528301887, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=320, Percent_Identity=30.3125, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=172, Percent_Identity=29.6511627906977, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=121, Percent_Identity=35.5371900826446, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=173, Percent_Identity=38.728323699422, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=39.8148148148148, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321612, Length=91, Percent_Identity=37.3626373626374, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24585318, Length=307, Percent_Identity=35.8306188925081, Blast_Score=144, Evalue=7e-35,
Organism=Drosophila melanogaster, GI20129375, Length=286, Percent_Identity=37.4125874125874, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24640873, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640877, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640875, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BRUA1 (B2S806)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935689.1
- ProteinModelPortal:   B2S806
- SMR:   B2S806
- GeneID:   6326829
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I17330
- HOGENOM:   HBG716038
- OMA:   RNRTGAK
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36789; Mature: 36789

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYR
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YQQHFKAKTGMHGMGRNMTGGKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCEEEEEHHHHHHHEEECCC
GNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIADAGLVGLPNAGKSTFLASVT
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEECCCEEECCCCCCCCEEEEEC
AAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVL
CCCCCCCCCCCEEECCCCCEEEECCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHH
LHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKAC
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GCEPLLLSAVSHEGLNDTLRQLARIIDLSRAEEAGTAQAEE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKFLDQAKIYIRSGNGGAGAVSFRREKFLEFGGPDGGDGGRGGDVWVEAVDGLNTLIDYR
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YQQHFKAKTGMHGMGRNMTGGKGDDVVLRVPVGTQIFEEDNETLICDITEVGQRYRLAKG
HHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCCEEEEEHHHHHHHEEECCC
GNGGFGNLHFTTSTNRAPRRANPGQEGIERTIWLRLKLIADAGLVGLPNAGKSTFLASVT
CCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEECCCEEECCCCCCCCEEEEEC
AAKPKIADYPFTTLHPNLGVARIDGREFVIADIPGLIEGASEGVGLGDRFLGHVERTRVL
CCCCCCCCCCCEEECCCCCEEEECCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHH
LHLVSAQEEDVAKAYQVIRGELEAYEHGLADKPEIVALSQVDTLDPETRKAKVKALKKAC
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
GCEPLLLSAVSHEGLNDTLRQLARIIDLSRAEEAGTAQAEE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA