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The map label for this gene is mdtA [H]

Identifier: 163845033

GI number: 163845033

Start: 888661

End: 889779

Strand: Reverse

Name: mdtA [H]

Synonym: BSUIS_B0909

Alternate gene names: 163845033

Gene position: 889779-888661 (Counterclockwise)

Preceding gene: 163845034

Following gene: 163845032

Centisome position: 63.52

GC content: 59.25

Gene sequence:

>1119_bases
ATGCAACGGGCTGCGCGAACAGGCAAATACCTGATTTTGGGCGCATTCGCCGGTCTTGCAACCTGCATTCAGATCCTGTC
GGCCGGAAGTCCGGCATATGCTGATTCACTCAATGTCGTGCCGGTTGCGGTCCGGGAAGCGAAGCTTGTCGATTACCAGC
CGAAATTGACGCTTTCCGGGGCTGTCGCCGCGCGCTCTCTGGTCAATGTATCGTTCCGCGTCAATGGTCAGGTGGTCGAA
CGGCTGGTCGATATCGGGCAGCATGTCGAAAAGGGGCAGCTTCTGGCCCGCATCGACGATGTTGAACAGCGCGCCAATAT
GCGCGTTGCGCAGGCTTCCATGGACGCCGCAGAAGCGCAGCTCGTGCAGGCCGACGCCAATTTCAAGCGCCAGCAGGCGC
TGTTGAAGCAGGGTTTTACCACGCGCAGCCAGTATGACCAGGCCGATCAGGCATTGCGCACCGCGCAAAGTGCGCTTTCC
AGCGCGCAAAGCCAGCTTGGCAATGCACGCGACGAGCTTTCCTATACCGAGCTTCATGCCCCTGTTTCAGGCGTCGTTAC
GGCGCGCAATATCGAAACGGGTCAGGTCGTGCAGGCAGCGCAAACGGCTTTCTCCATTGCGGAAGACGGCTCGCGCGACG
CTATTTTCGATGTGCAGGAAACATTGGTGAATCATGCCCGCATTGGAATGGGCGTAACGGTTGCCCTGCTTGCCGATCCT
TCCATTGAAGCAGAGGGCAATATCCGTGAATTGTCGCCGGTTGTTGACGCACAGACCGGCACAGTGGGGGTCAAGGTAGG
CATTGCGCAGGCAACTGCGCAGATGGCGCTTGGCGCAATCGTCACCGGAACTGTCCATATGGATGCGCGGCAGGTGATCG
TGCTGCCATGGAGCGCGATGACCTCGGAGGCGGGACGAACGGCCGTCTGGCGCGTGGATAGGGACACGCATGTCGCGACA
CTCGTTCCGATCAAGGTGCTGGCCTATGAAAAAGAGCGCGTGATCGTCGAAAGCGGCCTTAATAAAGGTGAGCTTATCGT
GACCAAAGGTGCGCAGATGCTGCGCTCCGGCGAGCCGGTAGAGATCATGCAGGGGCCTGAAGGAGCTGGCTCGCAATGA

Upstream 100 bases:

>100_bases
TTTTGATTGCATTCTCACGGCAACCAAACAAACGAGAATCGTGTAAATGGCGGTAATATCGTTCCCTGAGACTATCCGGG
GCGAATGGGGGCGCGTTGCA

Downstream 100 bases:

>100_bases
AAATCCATATGAACCCCATGTTCCGTGCTGCCGGTTGCGCGGTCCTGTTTGGCGCGCTGACGGTGCTTGCCGCTTGCGGC
AAAGAGGATGAAAAGGCGCA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MQRAARTGKYLILGAFAGLATCIQILSAGSPAYADSLNVVPVAVREAKLVDYQPKLTLSGAVAARSLVNVSFRVNGQVVE
RLVDIGQHVEKGQLLARIDDVEQRANMRVAQASMDAAEAQLVQADANFKRQQALLKQGFTTRSQYDQADQALRTAQSALS
SAQSQLGNARDELSYTELHAPVSGVVTARNIETGQVVQAAQTAFSIAEDGSRDAIFDVQETLVNHARIGMGVTVALLADP
SIEAEGNIRELSPVVDAQTGTVGVKVGIAQATAQMALGAIVTGTVHMDARQVIVLPWSAMTSEAGRTAVWRVDRDTHVAT
LVPIKVLAYEKERVIVESGLNKGELIVTKGAQMLRSGEPVEIMQGPEGAGSQ

Sequences:

>Translated_372_residues
MQRAARTGKYLILGAFAGLATCIQILSAGSPAYADSLNVVPVAVREAKLVDYQPKLTLSGAVAARSLVNVSFRVNGQVVE
RLVDIGQHVEKGQLLARIDDVEQRANMRVAQASMDAAEAQLVQADANFKRQQALLKQGFTTRSQYDQADQALRTAQSALS
SAQSQLGNARDELSYTELHAPVSGVVTARNIETGQVVQAAQTAFSIAEDGSRDAIFDVQETLVNHARIGMGVTVALLADP
SIEAEGNIRELSPVVDAQTGTVGVKVGIAQATAQMALGAIVTGTVHMDARQVIVLPWSAMTSEAGRTAVWRVDRDTHVAT
LVPIKVLAYEKERVIVESGLNKGELIVTKGAQMLRSGEPVEIMQGPEGAGSQ
>Mature_372_residues
MQRAARTGKYLILGAFAGLATCIQILSAGSPAYADSLNVVPVAVREAKLVDYQPKLTLSGAVAARSLVNVSFRVNGQVVE
RLVDIGQHVEKGQLLARIDDVEQRANMRVAQASMDAAEAQLVQADANFKRQQALLKQGFTTRSQYDQADQALRTAQSALS
SAQSQLGNARDELSYTELHAPVSGVVTARNIETGQVVQAAQTAFSIAEDGSRDAIFDVQETLVNHARIGMGVTVALLADP
SIEAEGNIRELSPVVDAQTGTVGVKVGIAQATAQMALGAIVTGTVHMDARQVIVLPWSAMTSEAGRTAVWRVDRDTHVAT
LVPIKVLAYEKERVIVESGLNKGELIVTKGAQMLRSGEPVEIMQGPEGAGSQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=319, Percent_Identity=25.0783699059561, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789929, Length=371, Percent_Identity=25.3369272237197, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081796, Length=310, Percent_Identity=28.7096774193548, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081951, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790519, Length=251, Percent_Identity=25.8964143426295, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786668, Length=317, Percent_Identity=26.1829652996845, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39491; Mature: 39491

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRAARTGKYLILGAFAGLATCIQILSAGSPAYADSLNVVPVAVREAKLVDYQPKLTLSG
CCCCHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCCEEEHH
AVAARSLVNVSFRVNGQVVERLVDIGQHVEKGQLLARIDDVEQRANMRVAQASMDAAEAQ
HHHHHHHEEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVQADANFKRQQALLKQGFTTRSQYDQADQALRTAQSALSSAQSQLGNARDELSYTELHA
HHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCC
PVSGVVTARNIETGQVVQAAQTAFSIAEDGSRDAIFDVQETLVNHARIGMGVTVALLADP
CHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
SIEAEGNIRELSPVVDAQTGTVGVKVGIAQATAQMALGAIVTGTVHMDARQVIVLPWSAM
CCCCCCCHHHHCHHHCCCCCCEEEEEEHHHHHHHHHHHHHEEEEEEECCCEEEEEECHHH
TSEAGRTAVWRVDRDTHVATLVPIKVLAYEKERVIVESGLNKGELIVTKGAQMLRSGEPV
HCCCCCEEEEEECCCCEEEEEEEEEEEEECCCEEEEECCCCCCCEEEECCHHHHHCCCCE
EIMQGPEGAGSQ
EEEECCCCCCCC
>Mature Secondary Structure
MQRAARTGKYLILGAFAGLATCIQILSAGSPAYADSLNVVPVAVREAKLVDYQPKLTLSG
CCCCHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCEEECCCCCEEEHH
AVAARSLVNVSFRVNGQVVERLVDIGQHVEKGQLLARIDDVEQRANMRVAQASMDAAEAQ
HHHHHHHEEEEEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVQADANFKRQQALLKQGFTTRSQYDQADQALRTAQSALSSAQSQLGNARDELSYTELHA
HHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHCC
PVSGVVTARNIETGQVVQAAQTAFSIAEDGSRDAIFDVQETLVNHARIGMGVTVALLADP
CHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC
SIEAEGNIRELSPVVDAQTGTVGVKVGIAQATAQMALGAIVTGTVHMDARQVIVLPWSAM
CCCCCCCHHHHCHHHCCCCCCEEEEEEHHHHHHHHHHHHHEEEEEEECCCEEEEEECHHH
TSEAGRTAVWRVDRDTHVATLVPIKVLAYEKERVIVESGLNKGELIVTKGAQMLRSGEPV
HCCCCCEEEEEECCCCEEEEEEEEEEEEECCCEEEEECCCCCCCEEEECCHHHHHCCCCE
EIMQGPEGAGSQ
EEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]